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KT 5823是cGMP依赖性蛋白激酶（PKG）的有效选择性抑制剂（体外IC50 = 234 nM）。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.18 mL | 100.9 mL | 201.8 mL |
| 0.5 mM | 4.04 mL | 20.18 mL | 40.36 mL |
| 1 mM | 2.02 mL | 10.09 mL | 20.18 mL |
| 5 mM | 0.4 mL | 2.02 mL | 4.04 mL |
*The above data is based on the productmolecular weight 495.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16021 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 495.53 |
| Formula | C29H25N3O5 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 126643-37-6 |
| Synonyms | KT5823, KT-5823 |
| SMILES | O=C([C@@]([C@]1(C)O[C@@H]2N3C4=C5N1C6=CC=CC=C6C5=C(CN(C)C7=O)C7=C4C8=CC=CC=C38)(C2)OC)OC |
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