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Naproxen sodium是一种非选择性的环氧合酶（COX）抑制剂，具有抗炎，解热和镇痛作用。对秋水仙碱引起的认知障碍和氧化应激具有神经保护作用。
靶点信息
| COX-2 | COX-1 | |||
| 5.2 μM | 8.7 μM |
| In vitro | DMSO | 3 mg/mL (11.89 mM) | |
| Water | 48 mg/mL (190.29 mM) | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 39.64 mL | 198.22 mL | 396.45 mL |
| 0.5 mM | 7.93 mL | 39.64 mL | 79.29 mL |
| 1 mM | 3.96 mL | 19.82 mL | 39.64 mL |
| 5 mM | 0.79 mL | 3.96 mL | 7.93 mL |
*The above data is based on the productmolecular weight 252.24. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10623 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 252.24 |
| Formula | C14H13NaO3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 26159-34-2 |
| SMILES | C[C@@H](C1=CC2=C(C=C1)C=C(C=C2)OC)C(=O)[O-].[Na+] |
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