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Verteporfin

促销

YAP 抑制剂

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产品目录号: A12658

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Verteporfin 5mg A12658-5
¥ 800.00
Verteporfin 10mg A12658-10
¥ 1,200.00
Verteporfin 25mg A12658-25
¥ 2,400.00
Verteporfin 50mg A12658-50
¥ 4,000.00
Verteporfin 10mM * 1mL in DMSO A12658-10mM-D
¥ 1,200.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Verteporfin is a small molecule that inhibits TEAD–YAP association and YAP-induced liver overgrowth. It is also a potent second-generation photosensitizing agent derived from porphyrin.

Verteporfin

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Chemical Information

目录号 A12658
Mechanism of action Inhibitor
分子量 718.79
化学分子式 C41H42N4O8
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 129497-78-5
Synonyms Visudyne, DB00460??CL 318,952??Benzoporphyrin D??Bpd-MA??AIDS350621??AIDS-350621??Benzoporphyrin derivative monoacid ring A.
SMILES code CC1=C(C2=CC3=NC(=CC4=C(C(=C(N4)C=C5C6(C(C(=CC=C6C(=N5)C=C1N2)C(=O)OC)C(=O)OC)C)C)CCC(=O)OC)C(=C3C)CCC(=O)O)C=C.CC1=C(C2=CC3=NC(=CC4=C(C(=C(N4)C=C5C6(C(C(=CC=C6C(=N5)C=C1N2)C(=O)OC)C(=O)OC)C)C)CCC(=O)O)C(=C3C)CCC(=O)OC)C=C
化学名称 trans-3,4-Dicarboxy-4,4a-dihydro-4a,8,14,19-tetramethyl-18-vinyl-23H,25H-benzo(b)porphine-9,13-dipropionic acid 3,4,9-trimethyl ester

Biological Activity

Description
Verteporfin is a small molecule that inhibits TEAD–YAP association and YAP-induced liver overgrowth. It is also a potent second-generation photosensitizing agent derived from porphyrin.
Targets
VDA (Endothelial cells)

Solubility

Solubility (25°C)* In vitro DMSO 100 mg/mL (139.12 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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