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Vinblastine sulfate在无细胞试验中抑制微管形成并抑制nAChR活性，IC50为8.9μM，用于治疗某些类型的癌症。
| In vitro | DMSO | 93 mg/mL (102.3 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 11 mL | 55 mL | 110 mL |
| 0.5 mM | 2.2 mL | 11 mL | 22 mL |
| 1 mM | 1.1 mL | 5.5 mL | 11 mL |
| 5 mM | 0.22 mL | 1.1 mL | 2.2 mL |
*The above data is based on the productmolecular weight 909.05. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13661 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 909.05 |
| Formula | C46H58N4O9.H2SO4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 143-67-9 |
| Synonyms | Vincaleukoblastine sulfate salt |
| SMILES | CCC1(CC2CC(C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O.OS(=O)(=O)O |
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