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Captopril disulfide是LTA4水解酶的可逆竞争性抑制剂（IC50 = 11 M）。Captopril已被证明是血管紧张素转化酶-1（ACE1）的一种，而不是ACE2（IC50 = 22 nM）。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.12 mL | 115.59 mL | 231.19 mL |
| 0.5 mM | 4.62 mL | 23.12 mL | 46.24 mL |
| 1 mM | 2.31 mL | 11.56 mL | 23.12 mL |
| 5 mM | 0.46 mL | 2.31 mL | 4.62 mL |
*The above data is based on the productmolecular weight 432.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13521 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 432.55 |
| Formula | C18H28N2O6S2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 64806-05-9 |
| Synonyms | SQ 14,551 |
| SMILES | C[C@H](CSSCC(C)C(=O)N1CCC[C@H]1C(=O)O)C(=O)N2CCC[C@H]2C(=O)O |
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