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Icilin是一种冷却剂，可激活新型的冷受体TRPM8（CMR1）和TRPA1（ANKTM1/TRPN1），它们是TRP离子通道家族的成员。在表达CMR1的HEK 293细胞中感应电流（EC50 = 0.36μM）。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 32.12 mL | 160.62 mL | 321.23 mL |
| 0.5 mM | 6.42 mL | 32.12 mL | 64.25 mL |
| 1 mM | 3.21 mL | 16.06 mL | 32.12 mL |
| 5 mM | 0.64 mL | 3.21 mL | 6.42 mL |
*The above data is based on the productmolecular weight 311.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13560 |
|---|---|
| 作用机制 | Activator (激活剂) |
| M. Wt | 311.3 |
| Formula | C16H13N3O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 36945-98-9 |
| Synonyms | AG 3-5 |
| SMILES | C1C=C(NC(=O)N1C2=CC=CC=C2O)C3=CC(=CC=C3)[N+](=O)[O-] |
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