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Cerubidine (Daunorubicin HCl, Rubidomycin HCl)

Cerubidine (Daunorubicin HCl, Rubidomycin HCl)

Name: Cerubidine (Daunorubicin HCl, Rubidomycin HCl)
SKU: A10194

目录号: A10194

Topoisomerase 抑制剂

Cerubidine (Daunorubicin HCl, Rubidomycin HCl) Chemical Structure

CAS NO. 23541-50-6

Cerubidine (Daunorubicin HCl,Rubidomycin HCl)通过插入和抑制大分子生物合成与DNA相互作用。这抑制了拓扑异构酶II的进程，该酶使DNA中的超螺旋松弛以进行转录。

库存：现货

规格	价格	数量
10 mg	￥ 600.00
25 mg	￥ 1,000.00
50 mg	￥ 1,600.00
100 mg	￥ 2,600.00
10mM * 1mL in DMSO	￥ 930.00

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产品详情

生物活性

Cerubidine (Daunorubicin HCl,Rubidomycin HCl)通过插入和抑制大分子生物合成与DNA相互作用。这抑制了拓扑异构酶II的进程，该酶使DNA中的超螺旋松弛以进行转录。

靶点信息

DNA synthesis (Cell-free assay)
20 nM(Ki)

溶解度 *

In vitro (25°C)	DMSO	93 mg/mL (164.9 mM)
	Water	93 mg/mL (164.9 mM)
	Ethanol	Insoluble
In vivo	Saline	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.73 mL	88.65 mL	177.3 mL
0.5 mM	3.55 mL	17.73 mL	35.46 mL
1 mM	1.77 mL	8.87 mL	17.73 mL
5 mM	0.35 mL	1.77 mL	3.55 mL

*The above data is based on the productmolecular weight 564.0 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10194
作用机制	Inhibitor (抑制剂)
M. Wt	564.0
Formula	C27H29NO10.HCl
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	23541-50-6
Synonyms	Daunorubicin HCl, Rubidomycin HCl
SMILES	C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)C)O)N)O.Cl