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AZD5438是有效的细胞周期蛋白依赖性激酶（CDK）1、2和9抑制剂（IC50值分别为16、6和20 nM）。
| In vitro | DMSO | 68 mg/mL (183.06 mM) | |
| Water | Insoluble | ||
| Ethanol | 68 mg/mL (183.06 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.92 mL | 134.59 mL | 269.18 mL |
| 0.5 mM | 5.38 mL | 26.92 mL | 53.84 mL |
| 1 mM | 2.69 mL | 13.46 mL | 26.92 mL |
| 5 mM | 0.54 mL | 2.69 mL | 5.38 mL |
*The above data is based on the productmolecular weight 371.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A11105 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 371.5 |
| Formula | C18H21N5O2S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 602306-29-6 |
| Synonyms | AZD-5438 |
| SMILES | CC1=NC=C(N1C(C)C)C2=NC(=NC=C2)NC3=CC=C(C=C3)S(=O)(=O)C |
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