LY2835219 (abemaciclib)

目录号: A12989

CDK4/6 抑制剂

LY2835219 (abemaciclib)

LY2835219 (abemaciclib) Chemical Structure

CAS NO. 1231929-97-7

LY2835219 (abemaciclib)是一种细胞周期蛋白依赖性激酶(CDK)抑制剂,靶向CDK4(cyclin D1)和CDK6(cyclin D3)细胞周期途径,具有潜在的抗肿瘤活性。

库存: 现货

规格 价格 数量
5 mg
¥ 600.00
10 mg
¥ 900.00
50 mg
¥ 1,100.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

LY2835219 (abemaciclib)是一种细胞周期蛋白依赖性激酶(CDK)抑制剂,靶向CDK4(cyclin D1)和CDK6(cyclin D3)细胞周期途径,具有潜在的抗肿瘤活性。
In vitro DMSO 6 mg/mL (11.84 mM)
Water Insoluble
Ethanol 8 mg/mL (15.79 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.74 mL 98.7 mL 197.4 mL
0.5 mM 3.95 mL 19.74 mL 39.48 mL
1 mM 1.97 mL 9.87 mL 19.74 mL
5 mM 0.39 mL 1.97 mL 3.95 mL

*The above data is based on the productmolecular weight 506.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12989
作用机制 Inhibitor (抑制剂)
M. Wt 506.59
Formula C27H32F2N8
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1231929-97-7
Synonyms LY 2835219, LY-2835219
SMILES CCN1CCN(CC1)CC2=CN=C(C=C2)NC3=NC=C(C(=N3)C4=CC5=C(C(=C4)F)N=C(N5C(C)C)C)F

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