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QNZ (EVP4593)

促销

NF-??B 抑制剂

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产品目录号: A12748

库存状态:中国现货中国现货

产品名 目录号 价格 数量
QNZ 5mg A12748-5
¥ 500.00
QNZ 10mg A12748-10
¥ 800.00
QNZ 25mg A12748-25
¥ 1,500.00
QNZ 50mg A12748-50
¥ 2,500.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

QNZ inhibits the activation of the transcription factor NF-κB and has been used to investigate NF-κB signaling.

QNZ (EVP4593)

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Chemical Information

目录号 A12748
Mechanism of action Inhibitor
分子量 356.4
化学分子式 C22H20N4O
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 545380-34-5
Synonyms CAY10470, CAY 10470, CAY-10470
SMILES code C1=CC=C(C=C1)OC2=CC=C(C=C2)CCNC3=NC=NC4=C3C=C(C=C4)N
化学名称 N4-?[2-?(4-?phenoxyphenyl)ethyl]-?4,?6-?quinazolinediamine

Biological Activity

Description
QNZ inhibits the activation of the transcription factor NF-κB and has been used to investigate NF-κB signaling.
Targets
TNF-α (Jurkat T cells) NF-κB (Jurkat T cells)
7 nM11 nM

Solubility

Solubility (25°C) * In vitro DMSO 5 mg/mL (14.02 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% hydroxyethyl cellulose 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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