微信关注
China
Total item
Cart Subtotal
￥ 0.00 产品详情
PD184352 (CI-1040)是一种ATP非竞争性MEK1/2抑制剂，在基于细胞的测定中，IC50为17 nM，对MEK1/2的选择性是对MEK5的100倍。
靶点信息
| MEK1 (Cell-free assay) | MEK2 (Cell-free assay) | |||
| 17 nM | 17 nM |
| In vitro (25°C) | DMSO | 92 mg/mL (192.19 mM) | |
| Water | Insoluble | ||
| Ethanol | 13 mg/mL (27.15 mM) | ||
| In vivo | 30% PEG400+0.5% Tween80+5% propylene glycol, pH 9 | 9 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.89 mL | 104.45 mL | 208.9 mL |
| 0.5 mM | 4.18 mL | 20.89 mL | 41.78 mL |
| 1 mM | 2.09 mL | 10.44 mL | 20.89 mL |
| 5 mM | 0.42 mL | 2.09 mL | 4.18 mL |
*The above data is based on the productmolecular weight 478.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10212 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 478.7 |
| Formula | C17H14ClF2IN2O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 212631-79-3 |
| Synonyms | CI-1040 |
| SMILES | C1CC1CONC(=O)C2=C(C(=C(C=C2)F)F)NC3=C(C=C(C=C3)I)Cl |
产品标签
Product Questions
Product Questions
No Questions
您还可能对下列产品感兴趣
RO5126766 (CH5126766)
RO5126766 (CH5126766)是对Raf和MEK丝裂原激活的蛋白激酶（MAPK）具有特异性的蛋白激酶抑制剂，具有潜在的抗肿…
Chlortetracycline Hydrochloride
Chlortetracycline Hydrochloride是一种特殊而有效的钙离子载体抗生素。
MEK inhibitor
MEK inhibitor是一种有效的MEK抑制剂，抗肿瘤剂。
AS703026 (Pimasertib)
AS703026 (Pimasertib)是一种新型的，选择性的，口服可生物利用的MEK1/2抑制剂，可抑制MM细胞的生长和存活以及…
Arctigenin
Arctigenin是抗氧化剂，消炎药，抗增殖药和抗病毒药。它通过抑制IκBα磷酸化和p65核移位来抑制LPS诱导的iNOS…
Cobimetinib (racemate)
Cobimetinib (racemate)是一种有效的，高度选择性的MEK1/2抑制剂。
Keywords:购买 PD184352 (CI-1040) | PD184352 (CI-1040) 供应商 | 订购 PD184352 (CI-1040) | PD184352 (CI-1040) 价格 | PD184352 (CI-1040) 生产商 | 订单 PD184352 (CI-1040) | PD184352 (CI-1040) 代理商 | 购买 212631-79-3| 212631-79-3 供应商 | 订购 212631-79-3 | 212631-79-3 价格 | 212631-79-3 生产商 | 订单 212631-79-3 | 212631-79-3 代理商|buy PD184352 (CI-1040) | PD184352 (CI-1040) Supplier | purchase PD184352 (CI-1040) | PD184352 (CI-1040) cost | PD184352 (CI-1040) manufacturer | order PD184352 (CI-1040) | PD184352 (CI-1040) distributor | buy 212631-79-3| 212631-79-3 Supplier | purchase 212631-79-3 | 212631-79-3 cost | 212631-79-3 manufacturer | order 212631-79-3 | 212631-79-3 distributor
联系我们
United StatesAdooq Bioscience
Toll Free: (866) 930-6790
Fax: +1-323-606-8156
Email: sales@adooq.com
Not your Region? View all Distributors
ADOOQ 产品质量保证
We promise all products to perform as described.