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Protein Kinase A (PKA)



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Catalog No. Product Name Application Product Information
A13584

A-3 Hydrochloride

PKA, PKG, Casein Kinase I and II 抑制剂
A-3 Hydrochloride is an inhibitor of PKA (cAMP-dependent protein kinase, Ki=4.3μM) and cGMP-dependent protein kinase, Ki=3.8μM, PKC (protein kinase C, Ki=47μM), casein kinase I and II, and MLCK (myosin light chain kinase) ( Ki=7.4μM).
A14868

PKA inhibitor fragment (6-22) amide

PKA 抑制剂
PKA inhibitor fragment (6-22) amide is a synthetic peptide that acts as a protein kinase inhibitor.
A15914

Dibutyryl-cAMP

PKA activator
Dibutyryl-cAMP is a cell-permeable PKA activator by mimicing the action of endogenous cAMP.
A16017

6-Bnz-cAMP sodium salt

PKA-selective activator
6-Bnz-cAMP is a PKA-selective activator. It regulates the PKA dependent signaling pathways.
A16028

cAMPS-Rp, triethylammonium salt

reversible PKA 抑制剂
Rp-cAMPS is a cell-permeable and reversible inhibitor of PKA (protein kinase A) (Ki = 11 uM). Rp-cAMPS is resistant to hydrolysis by phosphodiesterases and is noncompetitive with respect to ATP.
A16016

KT 5720

PKA 抑制剂
KT 5720 is prepared by a modificiation of K-252a (sc-200517), which is synthesized by the fungus Nocardiopsis sp.
A16031

PKI 14-22 amide, myristoylated

PKA 抑制剂
PKI 14-22 amide, myristoylated is a useful heat stable cAMP-dependent protein kinase inhibitor. This is often used to study PKA in cellular systems in-vitro.
A16052

cGMP Dependent Kinase Inhibitor Peptid

PKG/PKA 抑制剂
cGMP Dependent Kinase Inhibitor Peptid is a specific cGKI (cyclic GMP-dependent protein kinase) inhibitor. Data indicates that it does not block cyclic GMP-dependent protein kinase phosphorylation of intact histones and has been used to study Plasmodium falciparum.
A16189

CCG215022

GRK2/5 抑制剂
CCG215022 is a potent GRK2 and GRK5 inhibitor. CCG215022 exhibited nanomolar IC50 values against both GRK2 and GRK5 and good selectivity against other closely related kinases such as GRK1 and PKA.
A15910

8-Bromo-cAMP

rprotein kinase A activator
8-Bromo-cAMP is a cell perbeable cyclic AMP (cAMP) analog and a PKA activator.
A15006

AT7867 2HCl

Akt 抑制剂
AT7867 dihydrochloride is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA with IC50 of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively, little activity outside the AGC kinase family.
A14307

NH125

eEF-2 抑制剂
NH125 is a selective eEF-2 kinase inhibitor.
A12464

AT13148

multi-AGC kinase 抑制剂
AT13148 is a novel oral multi-AGC kinase inhibitor with potent pharmacodynamic and antitumor activity, which shows a distinct mechanism of action from other AKT inhibitors.
A11935 SALE

H 89 2HCl

PKA 抑制剂
H 89 dihydrochloride is a cell-permeable, selective, reversible, ATP-competitive and potent inhibitor of protein kinase.
A10286 SALE

Daphnetin

EGFR, PKA,PKC 抑制剂
Daphnetin is a coumarin analog that acts as an inhibitor of several protein kinases. It inhibits EGFR kinase (IC50 = 7.67 µM), PKA (IC50 = 9.33 µM), and PKC (IC50 = 25 µM), in vitro. The inhibition of EGFR kinase by daphnetin was competitive to ATP and non-competitive to the peptide substrate. Also acts as a potent antioxidant and anti-malarial agent.
A11034 SALE

A-674563

Akt 抑制剂
A-674563 is a B/Akt inhibitor with an IC50 of 14 nM and also shows inhibitory activity against PKA and CDK2 with IC50 of 16 and 46 nM, respectively.
A16222

Synaptamide

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Synaptamide is a potent mediator for neurogenic differentiation of NSCs acting through PKA/CREB activation.

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