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MEK 抑制剂

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产品目录号: A11040


产品名 目录号 价格 数量
TAK-733 5mg A11040-5
¥ 900.00
TAK-733 10mg A11040-10
¥ 1,600.00
TAK-733 50mg A11040-50
¥ 4,500.00
TAK-733 100mg A11040-100
¥ 7,500.00
TAK-733 10mM * 1mL in DMSO A11040-10mM-D
¥ 1,200.00



TAK-733 is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic activity.





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Chemical Information

目录号 A11040
Mechanism of action Inhibitor
分子量 504.2
化学分子式 C17H15F2IN4O4
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1035555-63-5
Synonyms TAK733
SMILES code CN1C2=C(C(=C(C1=O)F)NC3=C(C=C(C=C3)I)F)C(=O)N(C=N2)C[C@H](CO)O
化学名称 (R)-3-(2,3-Dihydroxypropyl)-6-fluoro-5-(2-fluoro-4-iodophenylamino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione

Biological Activity

TAK-733 is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic activity.
3.2 nM


Solubility (25°C)* In vitro DMSO 101 mg/mL (200.3 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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