ELQ-300 is a potent and orally bioavailable antimalarial agent, acts as an inhibitor of the reductive (Qi) site of the cytochrome bc1 complex (cyt bc1). 了解更多

QNZ46 is a NR2C/NR2D-selective NMDA receptor non-competitive antagonist (IC50 values are 3, 6, 229, and >300, >300 μM for NR2D, NR2C, NR2A, NR2B, and GluR1, respectively). 了解更多

SARS-Nucleocapsid protein, Polyclonal Antibody 了解更多

SARS-Spike protein, Polyclonal Antibody 了解更多

Hypotaurine (2-aminoethanesulfinic acid), an intermediate in taurine biosynthesis from cysteine in astrocytes, is an endogenous inhibitory amino acid of the glycine receptor. 了解更多

TP0427736 is a potent inhibitor of ALK5 kinase activity with an IC50 of 2.72 nM and this effect is 300-fold higher than the inhibitory effect on ALK3 (IC50 = 836 nM for ALK3). It also inhibits Smad2/3 phosphorylation in A549 cells induced by TGF-β1 with an IC50 value of 8.68 nM. 了解更多

Indirubin-5-sulfonate is a cyclin-dependent kinase (CDK) inhibitor, with IC50 values of 55 nM, 35 nM, 150 nM, 300 nM and 65 nM for CDK1/cyclin B, CDK2/cyclin A, CDK2/cyclin E, CDK4/cyclin D1, and CDK5/p35, respectively. 了解更多

MM 07 is a biased apelin receptor agonist, with a KD of 300 nM in CHO-K1 cells and a KD of 172 nM in human heart. 了解更多

3-Hydroxybutyric acid is a butyric acid substituted with a hydroxyl group in the beta or 3 position. 了解更多

Indotecan (LMP-400) is a potent topoisomerase 1(Top1) inhibitor with IC50 values of 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively. 了解更多

Y-27632 is an ATP-competitive inhibitor of ROCK-I and ROCK-II, with Ki of 220 nM and 300 nM for ROCK-I and ROCK-II, respectively. 了解更多

AZ82 is a selective kinesin-like protein KIFC1 (HSET/KIFC1) inhibitor, with a Ki of 43 nM and an IC50 of 300 nM for KIFC1. 了解更多

Chlorantraniliprole is an insecticide that potently and selectively activates insect ryanodine receptor, with EC50s of 40 nM and 50 nM for Drosophila melanogaster and H. virescens ryanodine receptor, and ?300-fold more potent than that in the mouse myoblast cell line, C2C12 (EC50, 14 μM). 了解更多

SRT 1460, a potent Sirtuin-1 (SIRT1) activator with an EC1.5 value of 2.9 μM, shows good selectivity for activation of SIRT1 versus SIRT2 and SIRT3 (EC1.5>300 μM), and is more potent than Resveratrol and the closest sirtuin homologues. 了解更多

PF-4191834 is a novel, potent and selective non-redox 5-lipoxygenase inhibitor effective in inflammation and pain with an IC50=229 nM. displays ~300-fold selectivity for 5-LOX over 12-LOX and 15-LOX, shows no activity toward the cyclooxygenase enzymes. 了解更多

JAK3-IN-2 is a potent and highly selective JAK3 inhibitor with IC50 of 0.15 nM. dispalys >4,300-fold selectivity over JAK1, JAK2 and TYK2, and other kinases BMX, EGFR, ITK and BTK; blocks cytokine signaling through JAK3, but not through other JAK family enzymes; inhibits IL-7 induced pSTAT5 in CD3+, CD8+ T cells with IC50 of 280 nM; sufficiently blocks the development of inflammation in a rat model of rheumatoid arthritis, while sparing hematopoiesis. 了解更多

Oxprenolol is an orally bioavailable β-adrenergic receptor (β-AR) antagonist (Ki = 7.10 nM in a radioligand binding assay using rat heart tissue). It is non-selective and inhibits both β1- and β2-ARs (Kds = 2.09 and 1.35 nM in isolated rat heart and uterus, respectively). Oxprenolol is selective for β-ARs over serotonin (5-HT) receptors in rat sarcolemmal membrane preparations (IC50s = 4.13 and 23,300 nM, respectively), but it binds to 5-HT1A receptors in rat hippocampus and 5-HT1B in rat striatum (Kis = 94.2 and 642 nM, respectively). 了解更多

Eptifibatide是有效的糖蛋白IIb/IIIa拮抗剂（GPIIb/IIIa； Kd = 120 nM），可抑制血小板凝集。 了解更多

YZ9是PFKFB3（6-磷酸果糖-2-激酶/果糖-2,6-二磷酸酶）抑制剂，IC50值为0.183μM。 了解更多

Quinine是金鸡纳各种物种的主要生物碱，奎尼丁的旋光异构体和抗疟疾，骨骼肌松弛剂。 了解更多

Recombinant Human Heparanase-1 WB Control 了解更多

Prothrombin Complex 了解更多

Furazolidone是合成的硝基呋喃衍生物，当用于对抗革兰氏阳性和革兰氏阴性细菌时具有杀菌或抑菌活性。 了解更多

i-Inositol是一种糖醇化合物。肌醇参与许多生物过程，包括胰岛素信号转导，细胞骨架转导等。 了解更多

Nitrofurantoin是一种用于治疗膀胱感染的抗生素，可抑制细菌DNA，RNA和细胞壁蛋白的合成。 了解更多

4-Aminoantipyrine是具有镇痛，抗炎和解热作用的氨基比林的代谢产物。 了解更多

4-Aminobenzoic acid是许多非哺乳动物生物（包括细菌和真菌）中四氢叶酸合成的中间体。 了解更多

Cefotaxime sodium是第三代头孢菌素抗生素。广谱抗生素，对多种革兰氏阳性和革兰氏阴性细菌具有活性。 了解更多

Chloroxylenol是一种广谱抗菌化合物，用于控制细菌，藻类，真菌和病毒。 了解更多

Dihydrostreptomycin sulfate是一种氨基糖苷类抗生素，用于治疗牛，猪和绵羊的细菌性疾病。Dihydrostreptomycin是链霉素的衍生物。 了解更多

Fenofibric acid是一种纤维蛋白，可作为降脂剂，降低低密度脂蛋白胆固醇和甘油三酸酯。 了解更多

SRT 1720是人类SIRT1（EC1.5 = 0.16μM）相对于最接近的瑟土因同系物SIRT2和SIRT3（SIRT2：EC1.5 = 37 uM；SIRT3：EC1.5> 300 uM）的选择性激活剂。 了解更多

Imipenem是一种默克科学家伯顿·克里斯滕森（Burton Christensen），威廉·利安扎（William Leanza）和肯尼思·怀唐格（Kenneth Wildonger）于1980年发现的静脉内使用的内酰胺类抗生素。 了解更多

Cyclo (-RGDfK)是一种有效的、选择性的整合素抑制剂。 了解更多

Berberine Sulfate是一种生物碱，由于其耐多药泵的外排作用，因此具有相对较弱的抗生素性能。 了解更多

Octopamine hydrochloride是一种无脊椎生物胺神经递质，与去甲肾上腺素相关，是肾上腺素受体激动剂。 了解更多

Megestrol Acetate是具有抗肿瘤特性的孕酮衍生物。 了解更多

Fidaxomicin是大环内酯家族的主要类似物，该大环内酯家族分别从三个不同属（猕猴桃属，Dactylosporangium和微单孢菌属）的三个不同组别分离，分别被称为利比霉素A3，头孢菌素B和梭菌素B1。非达霉素是一种窄谱抗生素，对革兰氏阳性细菌特别是艰难梭菌具有极好的活性。非达霉素在胃肠道中起作用而不会过度破坏肠道微生物菌群。 了解更多

Orlistat是一种一般的脂肪酶抑制剂，对人十二指肠液的PL的IC50为122 ng / ml。 了解更多

Indinavir sulfate是HIV-1蛋白酶抑制剂。 了解更多

Azacyclonol，也称为γ-pipradol，是一种用于减少精神病患者幻觉的药物。 了解更多

Prilocaine 是一种氨基酰胺类的局部麻醉剂。它作用于神经元细胞膜上的钠离子通道，限制癫痫发作的扩散。 了解更多

Pitavastatin calcium (Livalo)是HMGCR（HMG-CoA还原酶）酶的竞争性抑制剂，可降低LDL胆固醇的合成。 了解更多

Nevirapine (Viramune)是有效的（IC50 = 84nM）HIV-1逆转录酶的选择性非核苷抑制剂。 了解更多

Mifepristone (Mifeprex)是一种抗氧化剂和糖皮质激素受体拮抗剂，具有抑制NFκB活化的能力，NFκB是一种影响各种粘附分子和几种炎症基因表达的核转录因子。 了解更多

Atracurium besylate是一种神经肌肉阻滞剂，ED95为0.2 mg/kg。 了解更多

Gabapentin Hydrochloride是一种加巴类似物。 了解更多

Efaproxiral通过非共价结合血红蛋白四聚体和降低血红蛋白-氧结合亲和力来增加缺氧肿瘤组织中的氧水平。 了解更多

Asiaticoside是植物积雪草的活性化学成分。积雪草苷用于研究伤口和烧伤的潜在治疗方法。 了解更多