微信关注
Total item
Cart Subtotal
￥ 0.00 产品详情
GDC-0152是caspases（Smac）的第二个线粒体激活物，具有潜在的抗肿瘤活性。
Targets
| Target | Value |
|---|---|
| MLXBIR3SG | ki: 14nM |
| cIAP1-BIR3 | ki: 17nM |
| XIAP-BIR3 | ki: 28nM |
| cIAP2-BIR3 | ki: 43nM |
| XIAP-BIR2 | ki: 112nM |
| cIAP2-BIR2 | ki: 9.6μM |
| cIAP1-BIR2 | ki: 14.5μM |
| In vitro (25°C) | DMSO | 98 mg/mL (196.53 mM) | |
| Water | 3 mg/mL (6.01 mM) | ||
| Ethanol | 98 mg/mL (196.53 mM) | ||
| In vivo | 30% propylene glycol, 5% Tween 80, 65% D5W | 4 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.05 mL | 100.27 mL | 200.55 mL |
| 0.5 mM | 4.01 mL | 20.05 mL | 40.11 mL |
| 1 mM | 2.01 mL | 10.03 mL | 20.05 mL |
| 5 mM | 0.4 mL | 2.01 mL | 4.01 mL |
*The above data is based on the productmolecular weight 498.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A14135 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 498.64 |
| Formula | C25H34N6O3S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 873652-48-3 |
| Synonyms | GDC0152, GDC 0152 |
| SMILES | CC(C(=O)NC(C1CCCCC1)C(=O)N2CCCC2C(=O)NC3=C(N=NS3)C4=CC=CC=C4)NC |
产品标签
Product Questions
Product Questions
No Questions
您还可能对下列产品感兴趣
Pluripotin (SC-1)
Pluripotin (SC-1)的活性是通过联合抑制RasGAP和ERK1介导的，其Kd值分别为98和212 nM。
Apoptosis Inhibitor (M50054)
Apoptosis Inhibitor (M50054)是细胞可渗透的凋亡诱导抑制剂。
YM155 (Sepantronium Bromide)
YM155 (Sepantronium Bromide)是一种新型小分子存活蛋白抑制剂，IC50为0.54 nM，可抑制存活蛋白启动子活性。
Birinapant (TL32711)
Birinapant (TL32711)是第二个线粒体衍生的胱天蛋白酶（SMAC）激活剂和IAP（凋亡蛋白抑制剂）家族蛋白抑制剂…
AT-406 (SM-406, ARRY-334543)
AT-406 (SM-406,ARRY-334543)是IAP家族蛋白质的口服生物利用抑制剂，具有潜在的凋亡诱导和抗肿瘤活性。AT-406选…
Keywords:购买 GDC-0152 | GDC-0152 供应商 | 订购 GDC-0152 | GDC-0152 价格 | GDC-0152 生产商 | 订单 GDC-0152 | GDC-0152 代理商 | 购买 873652-48-3| 873652-48-3 供应商 | 订购 873652-48-3 | 873652-48-3 价格 | 873652-48-3 生产商 | 订单 873652-48-3 | 873652-48-3 代理商|buy GDC-0152 | GDC-0152 Supplier | purchase GDC-0152 | GDC-0152 cost | GDC-0152 manufacturer | order GDC-0152 | GDC-0152 distributor | buy 873652-48-3| 873652-48-3 Supplier | purchase 873652-48-3 | 873652-48-3 cost | 873652-48-3 manufacturer | order 873652-48-3 | 873652-48-3 distributor