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IAPs antagonist
AZD5582 is an antagonist of the inhibitor of apoptosis proteins (IAPs), which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively.
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IAP antagonist
MV1 is an antagonist of IAP (inhibitor of apoptosis protein), leads to protein knockdown of HaloTag-fused proteins when combined with HaloTag ligand.
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14.3.3 proteins 拮抗剂
R18是14.3.3蛋白的拮抗剂(KD≈80 nM)。竞争性地抑制14.3.3-配体相互作用,而无需磷酸化。
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