2018-2019 AdooQ 最新目录册 点击此处下载
微信关注
申请试用装

Products On Sale



产品 1 到 50 共 1758个

每页
页面:
  1. 1
  2. 2
  3. 3
  4. 4
  5. 5

设置升序顺序
Catalog No. Product Name Application Product Information Sale Price
A10250

Regorafenib (BAY 73-4506) SALE

VEGFR 抑制剂
Regorafenib (BAY 73-4506) is a multikinase inhibitor with IC50 of 17, 40 and 69 nM c-KIT, VEGFR2, B-Raf. Regorafenib (BAY 73-4506) is an orally bioavailable multikinase inhibitor targeting both the tumor and its vasculature.

Special Price Starting at: ¥ 500.00

A10251

Flupirtine maleate SALE

NMDA 拮抗剂
Non-opioid analgesic with muscle relaxant properties.

Special Price Starting at: ¥ 300.00

A10253

Ostarine (MK-2866, GTx-024) SALE

Androgen Receptor Modulators
Ostarine is an androgen receptor modulator (SARM)

Special Price Starting at: ¥ 1,500.00

A10255

ABT-737 SALE

Bcl-2 抑制剂
ABT-737 is a pan-Bcl-2 inhibitor. IC50 values ranged from 192 nM (the pre-B cell line Hal-01) to <10 μM (Nalm-6, K562 and HL-60).

Special Price Starting at: ¥ 500.00

A10256

PD0325901 SALE

MEK 抑制剂
PD0325901 is MEK inhibitor and non-competitive with ATP, Kiapp of 1 nM against activated MEK1 and MEK2.

Special Price Starting at: ¥ 450.00

A10258

GDC-0449 (Vismodegib) SALE

Hedgehog 拮抗剂
GDC-0449 (Vismodegib) is a more potent novel and specific synthetic oral hedgehog pathway inhibitor with an IC50 of 3 nM.

Special Price Starting at: ¥ 500.00

A10259

Imatinib (Gleevec) SALE

PDGFR 抑制剂
Imatinib (Gleevec) is a number of tyrosine kinase enzymes specific inhibitor.

Special Price Starting at: ¥ 600.00

A10022

ABT-263 (Navitoclax) SALE

Bcl-2 抑制剂
ABT-263 (Navitoclax) is a potent orally bioavailable SMI that is structurally related to ABT-737. ABT-263 disrupts Bcl-2 - Bcl-XL interactions with pro-apoptotic proteins .

Special Price Starting at: ¥ 500.00

A10562

MDV3100 SALE

Androgen receptor 拮抗剂
MDV3100 is androgen-receptor inhibitor. Highly recommended inhibitor in AR research.

Special Price Starting at: ¥ 600.00

A10665

Obatoclax mesylate (GX15-070) SALE

Bcl-2 抑制剂
Bcl-2 homology domain-3 (BH3) mimetic,antagonize all antiapoptotic Bcl-2 family proteins (average IC50, 3 umol/L), including Mcl-1 (IC50, 2.9 umol/L) and Bfl-1 (IC50, 5 umol/L).

Special Price Starting at: ¥ 900.00

A10963

Vandetanib (ZD6474) SALE

VEGFR 抑制剂
Vandetanib (Zactima) is a VEGFR and EGFR antagonist and a tyrosine kinase inhibitor with IC50 of 60, 90, 40 nM for HUVEC proliferation, PC-9 cells and tyrosine kinase activity, respectively.

Special Price Starting at: ¥ 600.00

A10802

RO4929097 SALE

Gamma-secretase 抑制剂
RO4929097 is an orally bioavailable, small-molecule gamma secretase (GS) inhibitor with an IC50 of 4 nM.

Special Price Starting at: ¥ 1,000.00

A10712

PF-2341066 (Crizotinib) SALE

ALK/ c-Met 抑制剂
PF-2341066 (Crizotinib) is an inhibitor of the c-Met kinase and the NPM-ALK. PF-2341066 inhibited cell proliferation in ALK-positive ALCL cells (IC50s=30 nM).

Special Price Starting at: ¥ 300.00

A10611

MS-275 (Entinostat) SALE

HDAC 抑制剂
MS-275 (Entinostat) is a potent HDAC inhibitor with IC50 of 0.3 and 8uM for HDAC1 and HDAC3, respectively.

Special Price Starting at: ¥ 400.00

A10758

PTC124 (Ataluren) SALE

CFTR 抑制剂
PTC124 also known as Ataluren is CFTR-G542X nonsense allele inhibitor.

Special Price Starting at: ¥ 400.00

A10001

Sorafenib (Nexavar) SALE

Raf 抑制剂
Sorafenib (Nexavar) is a novel, small molecular inhibitor of several tyrosine protein kinases (VEGFR and PDGFR) and RAF/MEK/ERK cascade inhibitor with an IC50 of 6, 22, 38 nM for Raf-1, wt BRAF and V599E mutant BRAF.

Special Price Starting at: ¥ 500.00

A10003

MK-2206 2HCl SALE

AKT 抑制剂
MK-2206 2HCl is a highly selective inhibitor of Akt1/2/3 with IC50 of 8 nM/12 nM/65 nM, respectively.

Special Price Starting at: ¥ 600.00

A10004

MLN8237 (Alisertib) SALE

Aurora A Kinase 抑制剂
MLN8237 (Alisertib) 是一种选择性Aurora A抑制剂,无细胞试验中IC50为1.2 nM,作用于Aurora A比作用于Aurora B选择性强200倍以上。Phase 3。

Special Price Starting at: ¥ 600.00

A10005

(-)-Epigallocatechin gallate SALE

Antioxidant, antiangiogenic, antitumor agent
(-)-Epigallocatechin gallate is a potent anti-oxidant polyphenol flavonoid isolated from green tea.

Special Price Starting at: ¥ 250.00

A10006

(-)-Huperzine A SALE

GluR 抑制剂
(-)-Huperzine A is a naturally occurring sesquiterpene alkaloid compound found in the firmoss Huperzia serrata.

Special Price Starting at: ¥ 300.00

A10547

LY294002 SALE

PI3K 抑制剂
LY294002 is a PI3k inhibitor (cell IC50 about 10 μM) and a casein kinase II inhibitor.

Special Price Starting at: ¥ 500.00

A10027

AC220 (Quizartinib) SALE

FLT3 抑制剂
AC220 (Quizartinib) is a uniquely potent and selective FLT3 inhibitor with IC50 of 0.56 ± 0.3 nM and >10 mM for MC4-11 and A375, respectively.

Special Price Starting at: ¥ 500.00

A10114

AZD8055 SALE

mTOR 抑制剂
AZD8055 is a potent, selective, and orally bioavailable ATP-competitive mTOR kinase inhibitor with an IC50 of 0.8 nM.

Special Price Starting at: ¥ 400.00

A10133

BEZ235 (NVP-BEZ235, Dactolisib) SALE

PI3K/mTOR 抑制剂
BEZ235 (NVP-BEZ235) inhibits PI3K and mTOR kinase activity by binding to the ATP-binding cleft of these enzymes.

Special Price Starting at: ¥ 300.00

A11002

YM155 (Sepantronium Bromide) SALE

Survivin 抑制剂
YM155 is a novel small molecule survivin suppressant with an IC50 of 0.54 nM for the inhibition of survivin promoter activity.

Special Price Starting at: ¥ 400.00

A10110

AZD1480 SALE

JAK 抑制剂
AZD1480 is a novel potent small JAK2 inhibitor with an IC50 of 0.26 nM.

Special Price Starting at: ¥ 500.00

A10461

Ibuprofen (Advil) SALE

COX-1 抑制剂
Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) targeting COX-1 with an IC50 of 13 μM.

Special Price Starting at: ¥ 400.00

A10448

Hesperadin SALE

Aurora B Kinase 抑制剂
Hesperadin is a human Aurora B inhibitor with an IC50 of 40 nM for the prevention of the phosphorylation of substrate. It markedly reduces the activity of AMPK, Lck, MKK1, MAPKAP-K1, CHK1 and PHK while it does not inhibit MKK1 activity in vivo.

Special Price Starting at: ¥ 800.00

A10860

SP600125 SALE

JNK 抑制剂
SP600125 is a JNK inhibitor with IC50=40 nM for JNK-1 and JNK-2 and 90 nM for JNK-3.

Special Price Starting at: ¥ 400.00

A10103

Axitinib SALE

VEGFR 抑制剂
Axitinib is a small molecule tyrosine kinase inhibitor,which inhibits multiple targets, including VEGFR-1, VEGFR-2, VEGFR-3, platelet derived growth factor receptor (PDGFR), and cKIT (CD117).

Special Price Starting at: ¥ 400.00

A10862

SRT1720 HCl SALE

SIRT1 Activator
SRT1720 is an inhibitor developed intended as a small-molecule activator of the sirtuin subtype SIRT1.

Special Price Starting at: ¥ 900.00

A10706

Pelitinib (EKB-569) SALE

EGFR 抑制剂
Pelitinib (EKB-569) is a 3-cyanoquinoline pan-ErbB tyrosine kinase inhibitor with potential antineoplastic activity.

Special Price Starting at: ¥ 700.00

A10701

PD 0332991 HCl (Palbociclib) SALE

CDK 4/6 抑制剂
PD 0332991 HCl is an orally available pyridopyrimidine-derived cyclin-dependent kinase (CDK) inhibitor with potential antineoplastic activity.

Special Price Starting at: ¥ 500.00

A10709

Perifosine (NSC-639966) SALE

Akt 抑制剂
Perifosine (also KRX-0401) acts as an Akt inhibitor and a PI3K inhibitor.

Special Price Starting at: ¥ 600.00

A10638

Neratinib (HKI-272) SALE

HER2 抑制剂
Neratinib (HKI-272) is a tyrosine kinase inhibitor.

Special Price Starting at: ¥ 500.00

A10408

FTY720 (Fingolimod) SALE

S1P Receptor 拮抗剂
FTY720 is a derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analog of sphingosine.

Special Price Starting at: ¥ 600.00

A10996

XL184 free base (Cabozantinib) SALE

VEGFR 抑制剂
XL184 free base (Cabozantinib) is a small molecule designed to inhibit multiple receptor tyrosine kinases, specifically MET and VEGFR2.

Special Price Starting at: ¥ 600.00

A10602

MLN9708 SALE

Proteasome 抑制剂
MLN9708 is a proteasome inhibitor, which inhibits the activity of the proteasome, blocking the targeted proteolysis normally performed by the proteasome.

Special Price Starting at: ¥ 600.00

A10390

Flavopiridol (Alvocidib) SALE

CDK 抑制剂
Flavopiridol (Alvocidib) is a cyclin-dependent kinase inhibitor under clinical development for the treatment of chronic lymphocytic leukemia.

Special Price Starting at: ¥ 400.00

A11016

BKM120 (NVP-BKM120, Buparlisib) SALE

PI3K 抑制剂?€?
BKM120 (NVP-BKM120) is a bioavailable specific oral pan-class I phosphatidylinositol 3-kinase (PI3K) kinase inhibitor.

Special Price Starting at: ¥ 600.00

A10739

PLX4032 (Vemurafenib) SALE

Raf 抑制剂
PLX4032 (Vemurafenib) also known as RG7204, Vemurafenib, R7204; RO5185426. PLX4032 is a B-raf inhibitor with an IC50 of 44 nM.

Special Price Starting at: ¥ 400.00

A10421

GDC-0941 (Pictilisib) SALE

PI3K 抑制剂
GDC-0941 is a potent, selective, orally bioavailable inhibitor of class I PI3 kinase (PI3K) , with IC50 values (nM) of 3, 33, 3, 75, 1230 and 580 for p110 α, β, δ and γ isoforms, DNA-PK and mTOR respectively.

Special Price Starting at: ¥ 400.00

A10199

CHIR-99021 SALE

GSK-3 抑制剂
CHIR99021 is an aminopyrimidine derivative that inhibits GSK3α and GSK3β with IC50 values of 10 and 6.7 nM, respectively.

Special Price Starting at: ¥ 500.00

A10108

Saracatinib (AZD0530) SALE

Src/Abl 抑制剂
Saracatinib (AZD0530) is a highly selective, orally available, dual-specific Src/Abl kinase inhibitor with IC50 of 2.7 and 30 nM for c-Src and Abl kinase, respectively.

Special Price Starting at: ¥ 600.00

A11018

TAK-875 (Fasiglifam) SALE

GPR 激动剂
TAK-875 is a potent, selective, and orally bioavailable GPR40 agonist.

Special Price Starting at: ¥ 1,000.00

A10208

CHR2797 (Tosedostat) SALE

Aminopeptidase 抑制剂
CHR-2797 (Tosedostat) is a novel metalloenzyme inhibitor that exerts antiproliferative effects against a range of tumor cell lines in vitro and in vivo and shows selectivity.

Special Price Starting at: ¥ 1,200.00

A10112

AZD6482 SALE

PI3K 抑制剂
AZD6482 is a PI3Kbeta inhibitor (IC50=0.021M) used in antithrombotic therapy.

Special Price Starting at: ¥ 900.00

A10558

Masitinib ( AB1010) SALE

c-Kit 抑制剂
Masitinib (AB1010) is a protein tyrosine kinase inhibitor.

Special Price Starting at: ¥ 500.00

A10211

Canertinib (CI-1033) SALE

HER2/ErbB2 抑制剂
Canertinib (CI-1033) is an irreversible tyrosine-kinase inhibitor with activity against EGFR (IC50 0.8 nM), HER-2 (IC50 19 nM) and ErbB-4 (IC50 7 nM).

Special Price Starting at: ¥ 500.00

A10769

R406 besylate SALE

Syk 抑制剂
R406 is an orally available spleen tyrosine kinase inhibitor with an IC50 of 41 nM.

Special Price Starting at: ¥ 500.00

产品 1 到 50 共 1758个

每页
页面:
  1. 1
  2. 2
  3. 3
  4. 4
  5. 5

设置升序顺序