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Nelfinavir

Catalog No. A11504
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HIV-1 protease 抑制剂

Nelfinavir是一种有效的口服生物可利用的人类免疫缺陷病毒HIV-1蛋白酶抑制剂(Ki=2 nM ),广泛用于与HIV逆转录酶抑制剂联合治疗HIV感染。了解更多

Product Citations (2)

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- Reiko Watanabe, .et al. Development of an In Silico Prediction Model for P-glycoprotein Efflux Potential in Brain Capillary Endothelial Cells toward the Prediction of Brain Penetration, J Med Chem, 2021, Mar 11;64(5):2725-2738 PMID: 33619967
- Yang PM, .et al. p38α/S1P/SREBP2 activation by the SAM-competitive EZH2 inhibitor GSK343 limits its anticancer activity but creates a druggable vulnerability in hepatocellular carcinoma, Am J Cancer Res, 2019, Oct 1;9(10):2120-2139 PMID: 31720078
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Pitavastatin Lactone

Catalog No. A13896
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HMG-CoA reductase 抑制剂

Pitavastatin Lactone是HMG-CoA还原酶抑制剂。了解更多

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Ledipasvir (GS 5885)

Catalog No. A13155
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NS5A 抑制剂

Ledipasvir (GS 5885)是丙型肝炎病毒HCV NS5A蛋白的抑制剂。了解更多

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- Sayuri Nitta, .et al. Impact of novel NS5A resistance-associated substitutions of hepatitis C virus detected in treatment-experienced patients, Scientific Reports, 2019, 9: 5722 PMID: 30952914
- Miyayama Y, .et al. Comparative study on the replication of HCV1b genome between wild type and cell culture adaptive mutant in regard to sensitivities against anti-HCV drugs, Microbiol Immunol, 2019, Dec 19 PMID: 31854467
- Sayuri Nitta, .et al. Effects of Resistance-Associated NS5A Mutations in Hepatitis C Virus on Viral Production and Susceptibility to Antiviral Reagents, Sci Rep, 2016, 6: 34652 PMID: 27703205
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Rosuvastatin

Catalog No. A11122
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HMG-CoA reductase 抑制剂

Rosuvastatin是用于治疗高胆固醇和相关疾病的抑制剂。了解更多

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