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搜索结果：“jwh 250”

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Prulifloxacin (Pruvel)

Catalog No. A11660
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Prulifloxacin (Pruvel)是氟喹诺酮类药物的一种较旧的合成化学治疗抗生素。与其他氟喹诺酮类药物一样，Prulifloxacin 通过抑制细菌DNA促旋酶来防止细菌DNA复制，转录，修复和重组。了解更多

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Carmofur

Catalog No. A10183
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Carmofur是用作抗肿瘤药的嘧啶类似物。它是氟尿嘧啶的衍生物。了解更多

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Camostat mesylate

Catalog No. A11764
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Camostat mesylate是胰蛋白酶样的蛋白酶抑制剂，抑制胰蛋白酶和各种炎症性蛋白酶，包括纤溶酶，激肽释放酶和凝血酶。了解更多

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Mitoxantrone Hydrochloride

Catalog No. A10596
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Mitoxantrone Dihydrochloride是一种抗病毒，抗菌，抗原生动物，免疫调节和抗肿瘤细胞抑制性蒽醌衍生物。了解更多

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Azithromycin (Zithromax)

Catalog No. A11803
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Azithromycin (Zithromax)是一种氮杂内酯类抗生素，可抑制革兰氏阴性细菌（如流感嗜血杆菌）的生长。了解更多

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- T Azuma ,etc. Detection of pharmaceuticals and phytochemicals together with their metabolites in hospital effluents in Japan, and their contribution to sewage treatment plant influents. Science of The Total Environment, 2016, 548-549:189-97..
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Indinavir sulfate

Catalog No. A11871
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Indinavir sulfate是HIV-1蛋白酶抑制剂。了解更多

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Lamivudine

Catalog No. A10512
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Lamivudine是一种有效的核苷类似物逆转录酶抑制剂(nRTI)。了解更多

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- Masaaki Toyama, .et al. Novel Neplanocin A Derivatives as Selective Inhibitors of Hepatitis B Virus with a Unique Mechanism of Action, Antimicrob Agents Chemother, 2022, Jun 21;66(6) PMID: 35604213
- Toyama M, .et al. Pyrimidotriazine derivatives as selective inhibitors of HBV capsid assembly, Virus Res, 2019, Oct 2;271:197677 PMID: 31376401
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Chloroquine Phosphate

Catalog No. A16445
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Chloroquine Phosphate是一种4-氨基喹啉抗疟和抗类风湿药，也可作为ATM活化剂。了解更多

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- Egawa Y, .et al. Therapeutic potential of CPI-613 for targeting tumorous mitochondrial energy metabolism and inhibiting autophagy in clear cell sarcoma, PLoS One, 2018, Jun 7;13(6):e0198940 PMID: 29879220
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Rosuvastatin

Catalog No. A11122
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HMG-CoA reductase 抑制剂

Rosuvastatin是用于治疗高胆固醇和相关疾病的抑制剂。了解更多

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Ivermectin

Catalog No. A10490
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Ivermectin是一种广谱抗寄生虫阿维菌素药物。了解更多

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Bepotastine Besilate

Catalog No. A11340
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Histamine Receptor 拮抗剂

Bepotastine Besilate是组胺H1受体激动剂。了解更多

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- Reiko Watanabe, .et al. Development of an In Silico Prediction Model for P-glycoprotein Efflux Potential in Brain Capillary Endothelial Cells toward the Prediction of Brain Penetration, J Med Chem, 2021, Mar 11;64(5):2725-2738 PMID: 33619967
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Ledipasvir (GS 5885)

Catalog No. A13155
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NS5A 抑制剂

Ledipasvir (GS 5885)是丙型肝炎病毒HCV NS5A蛋白的抑制剂。了解更多

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- Sayuri Nitta, .et al. Impact of novel NS5A resistance-associated substitutions of hepatitis C virus detected in treatment-experienced patients, Scientific Reports, 2019, 9: 5722 PMID: 30952914
- Miyayama Y, .et al. Comparative study on the replication of HCV1b genome between wild type and cell culture adaptive mutant in regard to sensitivities against anti-HCV drugs, Microbiol Immunol, 2019, Dec 19 PMID: 31854467
- Sayuri Nitta, .et al. Effects of Resistance-Associated NS5A Mutations in Hepatitis C Virus on Viral Production and Susceptibility to Antiviral Reagents, Sci Rep, 2016, 6: 34652 PMID: 27703205
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Pitavastatin Lactone

Catalog No. A13896
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HMG-CoA reductase 抑制剂

Pitavastatin Lactone是HMG-CoA还原酶抑制剂。了解更多

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Nelfinavir

Catalog No. A11504
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HIV-1 protease 抑制剂

Nelfinavir是一种有效的口服生物可利用的人类免疫缺陷病毒HIV-1蛋白酶抑制剂(Ki=2 nM ),广泛用于与HIV逆转录酶抑制剂联合治疗HIV感染。了解更多

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- Reiko Watanabe, .et al. Development of an In Silico Prediction Model for P-glycoprotein Efflux Potential in Brain Capillary Endothelial Cells toward the Prediction of Brain Penetration, J Med Chem, 2021, Mar 11;64(5):2725-2738 PMID: 33619967
- Yang PM, .et al. p38α/S1P/SREBP2 activation by the SAM-competitive EZH2 inhibitor GSK343 limits its anticancer activity but creates a druggable vulnerability in hepatocellular carcinoma, Am J Cancer Res, 2019, Oct 1;9(10):2120-2139 PMID: 31720078

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