VX-702

VX-702 Chemical Structure

CAS NO. 479543-46-9, 745833-23-2

VX-702是一种高选择性p38α MAPK抑制剂,可抑制血小板激动剂诱导的p38激活(IC50 = 4至20 nM)。

库存: 现货

规格 价格 数量
10 mg
¥ 280.00
50 mg
¥ 700.00
100 mg
¥ 1,330.00
200 mg
¥ 2,240.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

VX-702是一种高选择性p38α MAPK抑制剂,可抑制血小板激动剂诱导的p38激活(IC50 = 4至20 nM)。
In vitro (25°C) DMSO 77 mg/mL (190.45 mM)
Water Insoluble
Ethanol Insoluble
In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.73 mL 123.67 mL 247.34 mL
0.5 mM 4.95 mL 24.73 mL 49.47 mL
1 mM 2.47 mL 12.37 mL 24.73 mL
5 mM 0.49 mL 2.47 mL 4.95 mL

*The above data is based on the productmolecular weight 404.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10982
作用机制 Inhibitor (抑制剂)
M. Wt 404.3
Formula C19H12F4N4O2
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 479543-46-9, 745833-23-2
Synonyms VX702, VX 702
SMILES C1=CC(=C(C(=C1)F)N(C2=NC(=C(C=C2)C(=O)N)C3=C(C=C(C=C3)F)F)C(=O)N)F

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