“Tutalthromycin second gen”的搜索结果
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BRD inhibitor
BETd-246 is a second-generation BET bromodomain (BRD) inhibitor, exhibiting superior selectivity, potency and antitumor activity.
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KDM 抑制剂
2,4-Pyridinedicarboxylic Acid是针对JMJD2A(KDM4A),KDM4C,KDM4E(IC50、1.4μM),KDM5B(IC50、3μM),KDM6A和 其他的2-氧合酶。
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2OG oxygenases 抑制剂
IOX1是2OG加氧酶(包括JmjC脱甲基酶)的有效且广谱抑制剂。
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DNA Methyltransferase 抑制剂
Decitabine是一种次甲基化剂,它通过抑制DNA甲基转移酶来使DNA次甲基化。
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- Borbala Szabo, .et al. Aspirin mediates its antitumoral effect through inhibiting PTTG1 in pituitary adenoma, J Clin Endocrinol Metab, 2022, Sep 5;dgac496 PMID: 36059148
- Sangni Qian, .et al. Hypermethylation of tumor suppressor lncRNA MEF2C-AS1 frequently happened in patients at all stages of colorectal carcinogenesis, Clin Epigenetics, 2022, Sep 5;14(1):111 PMID: 36064442
- Borb??la Szab??, .et al. Demethylation status of somatic DNA extracted from pituitary neuroendocrine tumors indicates proliferative behavior, J Clin Endocrinol Metab, 2020, Jun 1;105(6):dgaa156 PMID: 32232382
- Bracha Shraibman, .et al. Human Leukocyte Antigen (HLA) Peptides Derived from Tumor Antigens Induced by Inhibition of DNA Methylation for Development of Drug-facilitated Immunotherapy, Mol Cell Proteomics, 2016, Sep; 15(9): 3058-3070 PMID: 27412690