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搜索结果：“rasgap ras p21”

“rasgap ras p21”的搜索结果

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Pluripotin (SC-1)

Catalog No. A11225
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ERK1/RasGAP 抑制剂

Pluripotin (SC-1)的活性是通过联合抑制RasGAP和ERK1介导的，其Kd值分别为98和212 nM。了解更多

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- Mohammad Azhar, .et al. Rational polypharmacological targeting of FLT3, JAK2, ABL, and ERK1 suppresses the adaptive resistance to FLT3 inhibitors in AML, Blood Adv, 2022, Aug 31 PMID: 36044389
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APS-2-79

Catalog No. A16231
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KSR/Ras 抑制剂

APS-2-79是RAF通过直接结合KSR活性位点而使MEK磷酸化的拮抗剂。了解更多

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LY3214996

Catalog No. A16843
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ERK 抑制剂

LY3214996是一种选择性的新型ERK1/2抑制剂，在生化分析中两种酶的IC50为5 nM。它有效抑制BRAF和RAS突变癌细胞系中的细胞磷酸RSK1。了解更多

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DEL-22379

Catalog No. A15802
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ERK 抑制剂

DEL-22379是一种有效的选择性ERK二聚体抑制剂，可抑制ERK二聚体而不影响ERK磷酸化，阻止由RAS-ERK途径癌基因驱动的肿瘤发生。了解更多

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