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Blasticidin S HCl

Catalog No. A14212
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Blasticidin S HCl是一种分离自gistreochromogenes链霉菌的核苷抗生素，并充当DNA和蛋白质合成抑制剂。了解更多

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INNO-206 (Aldoxorubicin)

Catalog No. A12326
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INNO-206 (Aldoxorubicin)是蒽环类抗生素阿霉素(DOXO-EMCH)的6-马来酰亚胺基腙衍生物前药，具有抗肿瘤活性。了解更多

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- Jingjing Ding, .et al. Self-Activatable Photo-Extracellular Vesicle for Synergistic Trimodal Anticancer Therapy, Adv Mater, 2021, Feb;33(7):e2005562 PMID: 33432702
- Dos Santos Câmara AL, .et al. Acid-sensitive lipidated doxorubicin prodrug entrapped in nanoemulsion impairs lung tumor metastasis in a breast cancer model, Nanomedicine (Lond), 2017, Aug;12(15):1751-1765 PMID: 28703043
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Clofarabine

Catalog No. A10228
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DNA/RNA Synthesis 抑制剂

Clofarabine具有抗肿瘤活性的第二代嘌呤核苷类似物。了解更多

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- Xie J, .et al. Optimization of a clofarabine-based drug combination regimen for the preclinical evaluation of pediatric acute lymphoblastic leukemia, Pediatr Blood Cancer, 2019, Dec 25:e28133 PMID: 31876116
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Cidofovir (Vistide)

Catalog No. A10214
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DNA/RNA Synthesis 抑制剂

Cidofovir (Vistide)通过选择性抑制病毒DNA的合成而抑制病毒复制。了解更多

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- Adhikary A, .et al. π-Radical to σ-Radical Tautomerization in One-Electron-Oxidized 1-Methylcytosine and Its Analogs, J Phys Chem B, 2015, Sep 3;119(35):11496-505 PMID: 26237072
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Ifosfamide

Catalog No. A10466
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Ifosfamide是一种细胞抑制剂，在结构上与环磷酰胺有关。了解更多

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Thiostrepton

Catalog No. A12890
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natural cyclic oligopeptide antibiotic

Thiostrepton抑制细菌蛋白质合成的抗生素。通过GTPase延长因子G（EF-G），EF-TU（GTP）催化的aa-tRNA传递和起始因子2（IF-2）的活性来抑制mRNA-tRNA易位。抗肿瘤剂；通过下调FOXM1表达来诱导乳腺癌细胞的细胞周期停滞和凋亡。了解更多

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Azithromycin (Zithromax)

Catalog No. A11803
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Azithromycin (Zithromax)是一种氮杂内酯类抗生素，可抑制革兰氏阴性细菌（如流感嗜血杆菌）的生长。了解更多

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- T Azuma ,etc. Detection of pharmaceuticals and phytochemicals together with their metabolites in hospital effluents in Japan, and their contribution to sewage treatment plant influents. Science of The Total Environment, 2016, 548-549:189-97..
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Mercaptopurine

Catalog No. A10568
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Mercaptopurine已显示出干扰DNA和RNA合成并引起从头嘌呤合成的抑制。了解更多

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Lomustine (CeeNU)

Catalog No. A10535
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Lomustine是一种烷基化亚硝脲化合物，具有类似于卡莫司汀的抗肿瘤活性，可引起DNA间交联。了解更多

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Tegafur

Catalog No. A10407
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DNA/RNA Synthesis 抑制剂

Tegafur是一种用于治疗癌症的化疗药物5-FU前药，是替加氟尿嘧啶的一种成分。了解更多

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- Takashi Azuma, .et al. Removal of pharmaceuticals in water by introduction of ozonated microbubbles, SEP PURIF TECHNOL, 2019, Apr; 212: 483-489
- Azuma T, .et al. Distribution of six anticancer drugs and a variety of other pharmaceuticals, and their sorption onto sediments, in an urban Japanese river, Environ Sci Pollut Res Int, 2017, Aug;24(23):19021-19030 PMID: 28660504
- Azuma T, .et al. Detection of pharmaceuticals and phytochemicals together with their metabolites in hospital effluents in Japan, and their contribution to sewage treatment plant influents, Sci Total Environ, 2016, Apr 1;548-549:189-197 PMID: 26802347
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Cisplatin

Catalog No. A10221
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Cisplatin是一种无机铂络合物，在肿瘤细胞中能够通过形成DNA加合物抑制 DNA synthesis。建议使用DMF溶解，而不是DMSO。了解更多

Product Citations (6)

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- RUI-NING LIANG, .et al. Kidney mesenchymal stem cells alleviate cisplatin-induced kidney injury and apoptosis in rats, Research Square, 2022, July 6th
- Wei Zeng, .et al. Lidocaine suppresses the malignant behavior of gastric cancer cells via the c-Met/c-Src pathway, Exp Ther Med, 2021, May; 21(5): 424 PMID: 33747163
- Yi-Ru Pan, .et al. ATM Inhibitor Suppresses Gemcitabine-Resistant BTC Growth in a Polymerase θ Deficiency-Dependent Manner, Biomolecules, 2020, Nov 9;10(11):1529 PMID: 33182492
- Amnah Alshangiti, .et al. The dietary flavonoid isoliquiritigenin is a potent cytotoxin for human neuroblastoma cells, Neuronal Signal, 2019, 2019
- Calhelha RC, .et al. Mathematical models of cytotoxic effects in endpoint tumor cell line assays: critical assessment of the application of a single parametric value as a standard criterion to quantify the dose-response effects and new unexplored proposal formats, Analyst, 2017, Oct 23;142(21):4124-4141 PMID: 28991301
- Pi-Lin Sung, .et al. Periostin in tumor microenvironment is associated with poor prognosis and platinum resistance in epithelial ovarian carcinoma, Oncotarget, 2016, Jan 26; 7(4): 4036-4047 PMID: 26716408