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搜索结果：“Tutalthromycin second gen”

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LEQ506

Catalog No. A20941
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Smo inhibitor

LEQ506 is a second-generation inhibitor of smoothened (Smo) with IC50s of 2 and 4 nM in human and mouse, respectively. 了解更多

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20(S)-Hydroxycholesterol

Catalog No. A21850
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Smo allosteric activator

20(S)-hydroxyCholesterol (20α-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo) that activates the hedgehog (Hh) signaling pathway with an EC50 of 3 μM in a gene transcription reporter assay using NIH3T3 cells. 了解更多

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