“cel”的搜索结果

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  1. Canertinib dihydrochloride

    Catalog No. A11344
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    EGFR inhibitor
    Canertinib dihydrochloride (CI-1033 dihydrochloride) is a potent and irreversible EGFR inhibitor; inhibits cellular EGFR and ErbB2 autophosphorylation with IC50s of 7.4 and 9 nM. 了解更多
  2. NSC 228155

    Catalog No. A16638
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    EGFR activator
    NSC 228155 is an activator of EGFR, binds to the extracellular region of EGFR and enhance tyrosine phosphorylation of EGFR. 了解更多
  3. Genistein

    Catalog No. A10425
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    EGFR inhibitor
    Genistein, a soy isoflavone, is a multiple tyrosine kinases (e.g., EGFR) inhibitor which acts as a chemotherapeutic agent against different types of cancer, mainly by altering apoptosis, the cell cycle, and angiogenesis and inhibiting metastasis. 了解更多
  4. c-Kit-IN-2

    Catalog No. A18440
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    c-KIT inhibitor
    c-Kit-IN-2 is a c-KIT inhibitor with an IC50 of 82 nM, shows superior antiproliferative activities against all the three GIST cell lines, GIST882, GIST430, and GIST48, with GI50s of 3, 1, and 2 nM, respectively. 了解更多
  5. ITK inhibitor 2

    Catalog No. A19096
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    ITK inhibitor
    ITK inhibitor 2 is a interleukin-2-inducible T-cell kinase (ITK) inhibitor extracted from patent WO2011065402A1, compound 4, with an IC50 of 2 nM. 了解更多
  6. CE-245677

    Catalog No. A19377
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    Tie2 and TrkA/B inhibitor
    CE-245677 is a potent reversible inhibitor of Tie2 and TrkA/B kinases with a cellular IC50s of 4.7 and 1 nM. 了解更多
  7. Dasatinib hydrochloride

    Catalog No. A15060
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    Src 抑制剂
    Dasatinib hydrochloride是一种有效的Abl/Src双重抑制剂,IC50分别<1 nM/0.8 nM。还可以抑制c-Kit(WT/c-Kit(D816V),IC50为79 nM/37 nM。有效,选择性Raf激酶抑制剂能够抑制野生型B-Raf,B-RafV600E和c -Raf的IC50值分别为3.2、0.8和5.0 nM。 了解更多
  8. Dasatinib (BMS-354825)

    Catalog No. A10290
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    Abl-Src 抑制剂
    Dasatinib (BMS-354825)是一种口服多BCR/ABL和Src家族酪氨酸激酶抑制剂。Dasatinib (BMS-354825)的主要靶标是BCR/ABL,Src,c-Kit,ephrin受体和其他几种酪氨酸激酶,但不是erbB激酶,例如EGFR或Her2。 了解更多

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