“Ligand-gated Ion Channels”的搜索结果

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  1. Raltegravir potassium

    Catalog No. A21403
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    integrase (IN) inhibitor
    Raltegravir is a potent integrase (IN) inhibitor, used to treat HIV infection. 了解更多
  2. Loviride

    Catalog No. A21996
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    non-nucleoside reverse transcriptase inhibitor
    Loviride (R 89439) is a non-nucleoside reverse transcriptase inhibitor (NNRTI), with an IC50 of 0.3 ?M for reverse transcriptase from HIV-1. Loviride (R 89439) inhibits HIV-1, HIV-2 and SIV replication in MT-4 cells. 了解更多
  3. Sofosbuvir impurity A

    Catalog No. A21641
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    HCV RNA replication inhibitor
    Sofosbuvir impurity A, an diastereoisomer of sofosbuvir, is the impurity of sofosbuvir. Sofosbuvir (PSI-7977) is an inhibitor of HCV RNA replication, demonstrates potent anti-hepatitis C virus activity. 了解更多
  4. Sofosbuvir impurity C

    Catalog No. A21636
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    HCV RNA replication inhibitor
    Sofosbuvir impurity C is the less active impurity of Sofosbuvir, Sofosbuvir is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity. 了解更多
  5. PSI-7976

    Catalog No. A21631
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    HCV RNA replication inhibitor
    PSI-7976 is the isomer of PSI-7977. PSI-7977 is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity. 了解更多
  6. Tenofovir alafenamide hemifumarate

    Catalog No. A18050
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    HIV-1 nucleotide reverse transcriptase inhibitor
    Tenofovir alafenamide hemifumarate (GS-7340 hemifumarate) is an investigational oral prodrug of Tenofovir. Tenofovir is a HIV-1 nucleotide reverse transcriptase inhibitor. 了解更多
  7. Tenofovir alafenamide fumarate

    Catalog No. A18049
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    HIV-1 nucleotide reverse transcriptase inhibitor
    Tenofovir alafenamide fumarate (GS-7340 fumarate) is an investigational oral prodrug of Tenofovir. Tenofovir is a HIV-1 nucleotide reverse transcriptase inhibitor. 了解更多
  8. R-1479

    Catalog No. A11540
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    HCV replication inhibitor
    R-1479 is a specific inhibitor of HCV replication in the HCV subgenomic replicon system (IC50=1.28 μM). 了解更多
  9. Mericitabine

    Catalog No. A11539
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    HCV NS5B polymerase inhibitor
    Mericitabine (RG 7128; R-7128) is a nucleoside inhibitor of the HCV NS5B polymerase that acts as an RNA chain terminator and prevents elongation of RNA transcripts during replication. 了解更多
  10. HIV-1 integrase inhibitor 2

    Catalog No. A11447
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    HIV-1 integrase inhibitor
    HIV-1 integrase inhibitor 2, in the treatment of human immunodeficiency virus (HIV) infection. 了解更多
  11. Zalcitabine

    Catalog No. A11005
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    nucleoside analogue reverse transcriptase inhibitor
    Zalcitabine is a potent nucleoside analogue reverse transcriptase inhibitor used in the treatment of HIV infection. 了解更多
  12. MIV-150

    Catalog No. A12060
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    NNRT inhibitor
    MIV-150 is a nonnucleoside reverse transcriptase (NNRT) inhibitor, blocking HIV-1 and HIV-2 infections, with an EC50<1 nM against HIV-1/HIV-2MN. 了解更多
  13. GLP-26

    Catalog No. A18914
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    HBV capsid assembly modulator
    GLP-26 is a HBV capsid assembly modulators (CAM), inhibits HBV DNA replication in Hep AD38 system (IC50=3 nM), and reduces cccDNA by >90% at 1 μM. GLP-26 disrupts the encapsidation of pre-genomic RNA, causes nucleocapsid disassembly and reduces cccDNA pools. 了解更多
  14. ML604086

    Catalog No. A18969
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    CCR8 抑制剂
    ML604086 is a selective CCR8 inhibitor, inhibiting CCL1 binding to CCR8 on circulating T-cells. ML604086 inhibits CCL1 mediated chemotaxis and increases in intracellular Ca2+ concentrations. 了解更多
  15. LMD-009

    Catalog No. A18643
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    CCR8 激动剂
    LMD-009 is a selective CCR8 nonpeptide agonist. LMD-009 mediates chemotaxis, inositol phosphate accumulation, and calcium release in high potencies with EC50s from 11 to 87 nM. 了解更多
  16. GSK2838232

    Catalog No. A15965
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    HIV maturation 抑制剂
    GSK2838232是一种新型的人类免疫病毒(HIV)成熟抑制剂,正在开发用于治疗慢性HIV感染。 了解更多
  17. Presatovir (GS-5806)

    Catalog No. A15835
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    Antiviral fusion 抑制剂
    Presatovir (GS-5806)是一种新型的,生物利用的RSV融合抑制剂,可抗多种RSV A和B临床分离株(平均EC50 = 0.43 nM)。 了解更多
  18. Fiacitabine

    Catalog No. A11422
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    HSV DNA replication 抑制剂
    Fiacitabine是单纯疱疹病毒(HSV)DNA复制的选择性抑制剂,HSV1和HSV2的IC50值分别为2.5 nM和12.6 nM。 了解更多
  19. Enfuvirtide Acetate(T-20)

    Catalog No. A15825
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    HIV fusion 抑制剂
    Enfuvirtide Acetate (T-20)是一个36个氨基酸的肽段,对应于gp41(HIV-1包膜蛋白的跨膜亚基)区域。 了解更多
  20. RO-9187

    Catalog No. A15224
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    HCV replication 抑制剂
    RO-9187是复制系统中HCV病毒复制的有效抑制剂(IC(50)= 171+/-12 nM;CC(50)> 1 mM)。 了解更多
  21. Bevirimat

    Catalog No. A14194
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    HIV-1 maturation 抑制剂
    Bevirimat (PA-457,MPC-4326,YK FH312) 是HIV-1病毒颗粒成熟抑制剂。 了解更多
  22. GSK2838232A

    Catalog No. A13156
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    HIV maturation 抑制剂
    GSK2838232是一种新型的人类免疫病毒(HIV)成熟抑制剂,正在开发用于治疗慢性HIV感染。 了解更多
  23. TMC353121

    Catalog No. A11585
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    RSV fusion 抑制剂
    TMC353121是一种有效的体外RSV融合抑制剂,pEC50 为 9.9。抗病毒药,也是治疗RSV疾病的新型候选药物。 了解更多
  24. Anguizole

    Catalog No. A11294
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    HCV replication 抑制剂
    Anguizole是一种抑制HCV复制并改变NS4B亚细胞分布的小分子。 了解更多

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