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Entecavir

Catalog No. A17569
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HBV inhibitor

Entecavir (SQ 34676; BMS 200475) is a potent and selective inhibitor of HBV, with an EC50 of 3.75 nM in HepG2 cell. 了解更多

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Loviride

Catalog No. A21996
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non-nucleoside reverse transcriptase inhibitor

Loviride (R 89439) is a non-nucleoside reverse transcriptase inhibitor (NNRTI), with an IC50 of 0.3 ?M for reverse transcriptase from HIV-1. Loviride (R 89439) inhibits HIV-1, HIV-2 and SIV replication in MT-4 cells. 了解更多

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RG7834

Catalog No. A21816
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HBV inhibitor

RG7834 (RO 7020322) is a highly selective and orally bioavailable HBV inhibitor, potently inhibits HBV antigens (both HBsAg and HBeAg) and HBV DNA, with IC50s of 2.8, 2.6, and 3.2 nM, respectively, in dHepaRG Cells. 了解更多

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NM107

Catalog No. A21761
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HCV NS5B polymerase

NM107 (2'-C-Methylcytidine) is an nucleoside inhibitor of the hepatitis C virus (HCV) NS5B polymerase, the EC50 of NM107 in the wild-type replicon cells is 1.85 μM. 了解更多

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ML604086

Catalog No. A18969
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CCR8 抑制剂

ML604086 is a selective CCR8 inhibitor, inhibiting CCL1 binding to CCR8 on circulating T-cells. ML604086 inhibits CCL1 mediated chemotaxis and increases in intracellular Ca2+ concentrations. 了解更多

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4'-Ethynyl-2'-deoxyadenosine

Catalog No. A18513
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nucleoside reverse transcriptase (RT) inhibitor

4'-Ethynyl-2'-deoxyadenosine (4'-E-dA), a nucleoside reverse transcriptase (RT) inhibitor, is an antiretroviral agent which is potent against drug-resistant HIV variants, with an EC50 of 98 nM in MT-4 cells for anti-HIV-1 activity. 了解更多

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Celgosivir

Catalog No. A13118
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alpha-glucosidase I 抑制剂

Celgosivir是一种用于潜在治疗HCV感染的α-葡萄糖苷酶I抑制剂。了解更多

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Maraviroc (UK-427857)

Catalog No. A10556
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CCR 拮抗剂

Maraviroc (UK-427857)是CCR5受体拮抗剂类别的抗逆转录病毒药物，用于治疗HIV感染。了解更多

Product Citations (3)

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- Roman V Uzhachenko, .et al. Metabolic modulation by CDK4/6 inhibitor promotes chemokine-mediated recruitment of T cells into mammary tumors, Cell Rep, 2021, Apr 6;35(1):108944 PMID: 33826903
- Karampoor S, .et al. Maraviroc attenuates the pathogenesis of experimental autoimmune encephalitis, Int Immunopharmacol, 2020, Mar;80:106138 PMID: 32007705
- Taisuke Ito, .et al. CCR5 is a novel target for the treatment of experimental alopecia areata, JCIA, 2020, 22 January