“Tutalthromycin second gen”的搜索结果
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PKCε activator
DCPLA-ME, the methyl ester form of DCPLA, is a potent PKCε activator for use in the treatment of neurodegenerative diseases.
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PKCδ inhibitor
BJE6-106 (B106) is a potent, selective 3rd generation PKCδ inhibitor with an IC50 of 0.05 μM and targets selectivity over classical PKC isozyme PKCα (IC50=50 μM).
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Ingenol Mebutate (PEP005)是一种存在于植物大戟汁液中的物质,是细胞死亡的诱导剂。
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- Yao-Yu Hsieh, .et al. Repurposing of ingenol mebutate for treating human colorectal cancer by targeting S100 calcium-binding protein A4 (S100A4), Toxicol Appl Pharmacol, 2022, Aug 15;449 PMID: 35724704
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TAK1/MAP4K2 抑制剂
NG25和TAK1抑制TLR7和TLR9激动剂激活IKK,并阻止Gen2.2细胞中这些配体诱导的1型IFN分泌。
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Smad 抑制剂
Kartogenin能有效诱导人骨髓间充质干细胞分化为软骨细胞。
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