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搜索结果：“jwh 250”

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BI-78D3

Catalog No. A13683
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JNK 抑制剂

BI-78D3是一种竞争性JNK（c-Jun N端激酶）抑制剂（IC50 = 280 nM），其选择性是p38α的100倍以上，在mTOR和PI-3K上无活性。 BI 78D3抑制JIP1（JNK相互作用蛋白1）JNK结合（IC50 = 500 nM）。了解更多

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TCS JNK 5a

Catalog No. A11969
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JNK 抑制剂 IX

TCS JNK 5a是JNK2和JNK3的高度选择性抑制剂（对于JNK3，JNK2，JNK1和p38β，pIC50值分别为6.7、6.5，<5.0和<4.8）。了解更多

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AS 602801 (Bentamapimod)

Catalog No. A11296
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JNK 抑制剂

AS 602801 (Bentamapimod)是一种新型口服活性Jun激酶抑制剂。了解更多

Product Citations (2)

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- Shuai Zhang, .et al. AS602801 sensitizes glioma cells to temozolomide and vincristine by blocking gap junction communication between glioma cells and astrocytes, J Cell Mol Med, 2021, Apr;25(8):4062-4072 PMID: 33609076
- Kuramoto K, .et al. AS602801, an Anti-Cancer Stem Cell Drug Candidate, Suppresses Gap-junction Communication Between Lung Cancer Stem Cells and Astrocytes, Anticancer Res, 2018, Sep;38(9):5093-5099 PMID: 30194154

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