“betaine hydrochloride”的搜索结果
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calcium channel blocker
Nicardipine hydrochloride (YC-93) is a calcium channel blocker with an IC50 of 1 μM for blocking cardiac calcium channels.
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Na+ channel blocker
Amiloride HCl是一种Na+通道阻滞剂,还抑制TRPP3通道和Na+/H+交换剂(NHE)。
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- Yu Y, .et al. Expression, Localization and Functional Activity of the Major Na+/H+ Exchange Isoforms Expressed in the Intestinal Cell Line Caco-2BBe, Cell Physiol Biochem, 2019, 52(5):1017-1038 PMID: 30977986
- Thomas D. Williams, .et al. The physiological regulation of macropinocytosis during Dictyostelium growth and development, J Cell Sci, 2018, Mar 15; 131(6): jcs213736 PMID: 29440238
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alpha-adrenergic blocking agent
Moxisylyte hydrochloride is an alpha-adrenergic blocking agent that is used in Raynaud's disease. It is also used locally in the eye to reverse the mydriasis caused by phenylephrine and other sympathomimetic agents.
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D2 receptor blocker
Trimethobenzamide hydrochloride is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting.
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Calcium channel blocker
Fendiline hydrochloride is a nonselective calcium channel blocker.
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T-type Ca2+ channel blocker
ABT-639 hydrochloride is a novel, peripherally acting, selective T-type Ca2+ channel blocker.
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β-adrenergic blocker
S(-)-Propranolol HCl是一种非选择性的β-肾上腺素能受体(βAR)拮抗剂,对β1AR和β2AR具有高亲和力,Ki值分别为1.8 nM和0.8 nM。 盐酸普萘洛尔抑制[3H] -DHA与大鼠脑膜制剂的结合,IC50为12 nM。
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K+ channel blocker?
E-4031 dihydrochloride是KV11.1(hERG)通道的选择性阻滞剂;禁止快速延迟整流器K+电流(IKr)。
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Sodium channel blocker
Encainide hydrochloride是一种钠通道阻滞剂,具有Ic类抗心律不齐的作用。Encainide是一种非手性抗心律失常药和苯甲酰苯胺衍生物。
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Calcium channel blocker
NNC 55-0396是Mibefradil衍生物,是一种高度选择性的T型钙通道阻滞剂;分别在INS-1细胞中抑制Cav3.1 T型通道和HVA电流的IC50值为6.8和> 100μM。
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Calcium channel blocker
Mibefradil dihydrochloride是钙通道阻滞剂,对T型Ca2+通道具有中等选择性,对T型和L型通道的IC50值分别为2.7 uM和18.6 uM。
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Ion channel blocker
Vernakalant hydrochloride是一种研究性混合离子通道阻滞剂,可以以2至5 mg/kg的剂量终止人的急性心房纤颤(AF),并且与现有药物相比,对房颤的选择性更高。在抗心律不齐的治疗中。
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- Joe Z.Zhang, .et al. A Human iPSC Double-Reporter System Enables Purification of Cardiac Lineage Subpopulations with Distinct Function and Drug Response Profiles, Cell Stem Cell, 2019, 24, 1-10
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K+/Na+/Ca+ Channel Blocker
Dronedarone Hydrochloride is a non-iodinated amiodarone derivative that inhibits Na+, K+ and Ca2+ currents.
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calcium channel blocker
Bepridil hydrochloride (CERM 1978) is a calcium channel blocker, with antianginal activity.
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TRP Channel blocker
SKF-96365 hydrochloride is a non-selective TRP Channel blocker.
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dual T-type and L-type calcium channel blocker
Efonidipine Hcl (NZ-105) is a dual T-type and L-type calcium channel blocker (CCB).
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oxidative phosphorylation blocker
Imeglimin hydrochloride是新型含四氢三嗪的口服降糖药中的第一个,即glimins。已证明它可作用于肝脏,肌肉和胰腺γ-细胞,以独特地靶向2型糖尿病的关键缺陷。
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dual T-type and L-type calcium channel blocker
Efonidipine hydrochloride monoethanolate (NZ-105 hydrochloride monoethanolate) is a dual T-type and L-type calcium channel blocker (CCB).
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