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Delgocitinib
Catalog No. A19234 JAK inhibitorDelgocitinib is a novel and specific JAK inhibitor with IC50s of 2.8, 2.6, 13 and 58 nM for JAK1, JAK2, JAK3 and Tyk2, respectively. 了解更多 -
BB-Cl-Amidine
Catalog No. A19265 -
Kv3 modulator 1
Catalog No. A19338 Kv3 voltage-gated potassium channel modulatorKv3 modulator 1 is a Kv3 voltage-gated potassium channel modulator extracted from patent WO2018020263A1, Compound X. Kv3 modulator 1 can be used to treat inflammatory pain. 了解更多 -
AGL-2263
Catalog No. A19525 -
EMDT oxalate
Catalog No. A19667 5-HT6 agonistEMDT oxalate is a selective 5-HT6 agonist, and has antidepressant effects. 了解更多 -
Dianicline dihydrochloride
Catalog No. A19775 α4β2 nicotinic acetylcholine receptor partial agonistDianicline dihydrochloride is a α4β2 nicotinic acetylcholine receptor partial agonist, a class of drugs that includes varenicline and cytisine for smoking cessation. 了解更多 -
Boc-C1-PEG2-C4-Cl
Catalog No. A20263 Boc-C1-PEG2-C4-Cl (PROTAC Linker 1) is a PROTAC linker utilized to connect the respective tyrosine kinase inhibitor (TKI) to the E3 recruiting ligand. 了解更多 -
Sigma-2 receptor antagonist 1
Catalog No. A20310 sigma-2 (??-2) receptor antagonistSigma-2 receptor antagonist 1 is a sigma-2 (??-2) receptor antagonist. 了解更多 -
Methyl-3β-hydroxycholenate
Catalog No. A20344 ROR gamma modulatorMethyl-3β-hydroxycholenate is a ROR gamma modulator extracted from patent US20110263046 A1, in figure 2. 了解更多 -
sulfo-SPDB-DM4
Catalog No. A20566 sulfo-SPDB-DM4 is a drug-linker conjugate for ADC by using the maytansinebased payload (DM4, an antitubulin agent) via the sulfo-SPDB linker. 了解更多 -
Methyl 13-cis-4-Oxoretinoate
Catalog No. A22639 -
Betahistine EP Impurity C
Catalog No. A22638 histamine H1 receptor agonist and H3 receptor antagonistBetahistine EP Impurity C (NSC19005) is an impurity of Betahistine. Betahistine is a potent, orally active and well-tolerated histamine H1 receptor agonist and H3 receptor antagonist used for the study of rheumatoid arthritis (RA). 了解更多 -
Tioxazafen
Catalog No. A22636 broad-spectrum seed treatment nematicideTioxazafen is a disubstituted oxadiazole and a broad-spectrum seed treatment nematicide. Tioxazafen is designed to provide consistent broad-spectrum control of nematodes in corn, soy, and cotton. 了解更多 -
Tracazolate
Catalog No. A22635 pyrazolopyridine anxiolyticTracazolate is a pyrazolopyridine anxiolytic known to interact with gamma-aminobutyric acid (GABA)(A) receptors, adenosine receptors, and phosphodiesterases. 了解更多 -
Gabazine free base
Catalog No. A22634 GABA receptor antagonistGabazine free base is a specific GABA receptor antagonist. Does not affect GABA-transaminase or glutamate-decarboxylase activitites. 了解更多 -
YM 298198 Hydrochloride
Catalog No. A22630 mGlu1 receptorsant agonistYM 298198 Hydrochloride is a non-competitive antagonist with high affinity and selectivity for mGlu1 receptors (Ki = 19 nM). 了解更多 -
PD184161
Catalog No. A22601 -
DCLK1-IN-1
Catalog No. A22319 chemical probeDCLK1-IN-1 is a selective, oral bioavailability in vivo-compatible chemical probe of the doublecortin like kinase 1 (DCLK1 kinase) domain. 了解更多 -
Clobenpropit dihydrobromide
Catalog No. A22263 histamine H3R antagonist/inverse agonistClobenpropit dihydrobromide is a potent histamine H3R antagonist/inverse agonist with a pEC50 of 8.07 for histamine H3LR. 了解更多 -
Philanthotoxin 74 dihydrochloride
Catalog No. A21739 AMPAR antagonistPhilanthotoxin 74 dihydrochloride (PhTx 74) is an AMPAR antagonist; inhibits GluR3 and GluR1 with IC50s of 263 and 296 nM, respectively. 了解更多 -
Centrinone
Catalog No. A20858 PLK4 inhibitorCentrinone (LCR-263) is a selective and reversible inhibitor of polo-like kinase 4 (PLK4) with a Ki of 0.16 nM. 了解更多 -
ABT-263 (Navitoclax)
Catalog No. A10022 Bcl-2 抑制剂ABT-263 (Navitoclax)是一种有效的Bcl-2家族抑制剂 (Bcl-2，Bcl-xL和Bcl-w的Ki <1 nmol/L)。ABT-263对Bcl- xL，Bcl-2和Bcl-w，( Ki≤1nmol/ L) 维持高亲和力，但与Mcl-1和A1的结合更弱。 了解更多
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