“pb 22”的搜索结果

产品 51 到 100 共 3389个

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  1. MCC950

    Catalog No. A22097
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    inhibitor of NLRP3 (NOD-like receptor (NLR) family
    MCC950 (CP-456773, CRID3) is a potent and selective inhibitor of NLRP3 (NOD-like receptor (NLR) family, pyrin domain-containing protein 3) with IC50 of 7.5 nM and 8.1 nM in BMDMs and HMDMs, respectively. 了解更多
  2. RBC10

    Catalog No. A22098
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    inhibitor of Ral binding to RALBP1
    RBC10 is an inhibitor of Ral binding to RALBP1 (the effector). 了解更多
  3. NIBR-0213

    Catalog No. A22099
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    S1P(1) antagonist
    NIBR-0213 is a potent and selective antagonist of S1P(1) with efficacy in experimental autoimmune encephalomyelitis. 了解更多
  4. SR8278

    Catalog No. A22100
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    nuclear heme receptor REV-ERB synthetic antagonist
    SR8278 is a competitive nuclear heme receptor REV-ERB synthetic antagonist. 了解更多
  5. BPU-11

    Catalog No. A22101
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    HCN4 CLP ligand
    BPU-11 is a HCN4 CLP ligand. It acts by modulating channel function and completely abolishing the cAMP-induced shift in V1/2. 了解更多
  6. CRANAD-28

    Catalog No. A22102
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    two-photon imaging probe
    CRANAD-28, a blood brain barrier (BBB) penetrable two-photon imaging probe, acts by labelling plaques and cerebral amyloid angiopathies (CAAs). 了解更多
  7. PD-089828

    Catalog No. A22103
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    ATP competitive inhibitor of FGFR-1, PDGFR-β and EGFR
    PD089828 is an ATP competitive inhibitor of FGFR-1, PDGFR-β and EGFR with IC50 of 0.15 ?M, 1.76 ?M, and 5.47 ?M, respectively. 了解更多
  8. RY785

    Catalog No. A22104
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    inhibitor of Kv2.1 and Kv2.2
    RY785 (Kv2-IN-A1) is an inhibitor of Kv2.1 and Kv2.2. 了解更多
  9. WAY-169916

    Catalog No. A22105
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    pathway-selective inhibitor of estrogen receptor (ER)
    WAY-169916 is a pathway-selective inhibitor of estrogen receptor (ER) that acts by inhibiting NF-kB transcriptional activity. 了解更多
  10. SGA360

    Catalog No. A22106
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    modulator of aryl hydrocarbon (Ah) receptor
    SGA360 is a selective modulator of aryl hydrocarbon (Ah) receptor that exhibits anti-inflammatory properties. 了解更多
  11. JCP174

    Catalog No. A22107
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    depalmitoylase inhibitor
    JCP174 is a depalmitoylase inhibitor that enhances Toxoplasma host-cell invasion by targeting TgPPT1. 了解更多
  12. AEM1

    Catalog No. A22108
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    inhibitor of deregulated NRF2 transcriptional activity
    AEM1 is an inhibitor of deregulated NRF2 transcriptional activity in cancer. 了解更多
  13. PS210

    Catalog No. A22109
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    protein kinase PDK1 inhibitor
    PS210 is a substrate-selective protein kinase PDK1 inhibitor that acts by binding to the PIF-pocket allosteric docking site. 了解更多
  14. RH01687

    Catalog No. A22110
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    β-cell protector
    RH01687 is a potent β-cell protector that exhibits β-cell-protective activities against endoplasmic reticulum (ER) stress. 了解更多
  15. BRD6688

    Catalog No. A22111
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    HDAC2 inhibitor
    BRD6688 is a selective inhibitor of HDAC2 that acts by enhancing the learning and memory processes. 了解更多
  16. Creatine riboside

    Catalog No. A22112
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    urinary metabolite
    Creatine riboside is a urinary metabolite and is a diagnostic and prognostic biomarker of lung cancer. 了解更多
  17. ONO-8130

    Catalog No. A22113
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    antagonist of EP1 receptor
    ONO-8130 is an orally available antagonist of EP1 receptor. 了解更多
  18. MSBN

    Catalog No. A22114
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    fluorogenic probe
    MSBN is a highly selective fluorogenic probe for thiols, selectively imaging thiols in live cells and specifically label protein thiols with a turn-on signal to determine diverse reversible protein thiol modifications. 了解更多
  19. Cytosporone B

    Catalog No. A22115
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    nuclear orphan receptor Nur77/NR4A1 agonist
    Cytosporone B (Csn-B; Dothiorelone G) is a naturally occurring nuclear orphan receptor Nur77/NR4A1 agonist with an EC50 of 0.278 nM. 了解更多
  20. GSK106 hydrochloride

    Catalog No. A22116
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    negative control compound
    GSK106 is a negative control compound that can be used in binding and functional assays for PAD4 inhibitors. 了解更多
  21. GSK121 trifluoroacetate

    Catalog No. A22117
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    PAD4 inhibitor
    GSK121 trifluoroacetate is a selective inhibitor of PAD4. 了解更多
  22. RO5203648 hydrochloride

    Catalog No. A22118
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    partial agonist of Trace amine-associated receptor 1
    RO5203648 hydrochloride is a partial agonist of Trace amine-associated receptor 1 (TAAR1). 了解更多
  23. NSC-45586

    Catalog No. A22119
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    pan-PHLPP inhibitor
    NSC-45586 is a pan-PHLPP inhibitor selective for PHLPP1 and PHLPP2. 了解更多
  24. FLTX1

    Catalog No. A22120
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    antiestrogenic properties
    FLTX1 is a fluorescent Tamoxifen derivative that can specifically label intracellular Tamoxifen-binding sites (estrogen receptors) under permeabilized and non-permeabilized conditions. FLTX1 exhibits the potent antiestrogenic properties of Tamoxifen in breast cancer cells. FLTX1 is devoid of the estrogenic agonistic effect on the uterus. 了解更多
  25. Epiblastin A

    Catalog No. A22121
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    inhibitor of Casein Kinase 1 (CK1)
    Epiblastin A is an inhibitor of Casein Kinase 1 (CK1) that engages CK1 isoenzymes in cell lysate and induces efficient conversion of epiblast stem cells (EpiSCs) into embryonic stem cells (cESCs). 了解更多
  26. ML198

    Catalog No. A22122
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    activator and non-inhibitory chaperone of glucocerebrosidase
    ML198 is a novel activator and non-inhibitory chaperone of glucocerebrosidase. 了解更多
  27. R243

    Catalog No. A22123
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    inhibitor of CCR8 signaling and chemotaxis
    R243 is an inhibitor of CCR8 signaling and chemotaxis. 了解更多
  28. BMS-986188

    Catalog No. A22124
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    Positive Allosteric Modulator of the delta-Opioid Receptor
    BMS-986188 is a novel Potent and Selective Positive Allosteric Modulator of the delta-Opioid Receptor. 了解更多
  29. BMS-986187

    Catalog No. A22125
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    positive allosteric modulator (PAM) of the δ-opioid receptor and a G-protein-biased allosteric agonist
    BMS-986187 is a potent and selective positive allosteric modulator (PAM) of the δ-opioid receptor and a G-protein-biased allosteric agonist. 了解更多
  30. NCGC607

    Catalog No. A22126
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    noninhibitory chaperone
    NCGC607 is a a noninhibitory chaperone of glucocerebrosidase (GCase). 了解更多
  31. PythiDC

    Catalog No. A22127
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    inhibitor of collagen prolyl 4-hydroxylase
    PythiDC is a selective inhibitor of collagen prolyl 4-hydroxylase. 了解更多
  32. GSK3 Inhibitor XIII

    Catalog No. A22128
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    ATP-binding site inhibitor of GSK-3
    GSK3 Inhibitor XIII (GSK3i XIII) is an ATP-binding site inhibitor of GSK-3. 了解更多
  33. MN58b

    Catalog No. A22129
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    choline kinase α (CHKα) inhibitor
    MN58b is a selective choline kinase α (CHKα) inhibitor, and results in inhibition of phosphocholine synthesis. 了解更多
  34. BGC201531

    Catalog No. A22130
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    EP4 antagonist
    BGC201531, also known as GTPL3380 and AP-1531, is a EP4 antagonist for the treatment of acute migraine. 了解更多
  35. TTK21

    Catalog No. A22131
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    CBP/p300 histone acetyltransferase activator
    TTK21 is a CBP/p300 histone acetyltransferase activator. 了解更多
  36. Statil

    Catalog No. A22132
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    aldose reductase inhibitor
    Ponalrestat, also known as MK-538, is an aldose reductase inhibitor. 了解更多
  37. MDK-1088

    Catalog No. A22133
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    Trypanosoma cruzi inhibitor
    MDK-1088 (T.cruzi Inhibitor) is a Trypanosoma cruzi inhibitor. 了解更多
  38. HZ-1157

    Catalog No. A22134
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    inhibitor of hepatitis C virus (HCV)
    HZ-1157 is an inhibitor of hepatitis C virus (HCV) with inhibitory activities toward HCV NS3/4A protease. 了解更多
  39. RGW 611

    Catalog No. A22135
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    anti-infective agent
    RGW 611, a morpholine derivative, is an impurity of Nimorazole, which is an anti-infective agent against anaerobic bacteria and protozoa. 了解更多
  40. (Z)-JIB-04

    Catalog No. A22137
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    Jumonji histone demethylase inihibitor
    Z-JIB-04 (NSC 693627, JIB-04 Z-isomer) is an isomer of JIB-04. JIB-04 is a pan-selective Jumonji histone demethylase inihibitor with IC50 of 230 nM, 340 nM, 855 nM, 445 nM, 435 nM, 1100 nM and 290 nM for JARID1A, JMJD2E, JMJD3, JMJD2A, JMJD2B, JMJD2C, and JMJD2D, respectively. 了解更多
  41. DS-1205b free base

    Catalog No. A22138
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    inhibitor of AXL kinase
    DS-1205b free base is a potent and selective inhibitor of AXL kinase, with an IC50 of 1.3 nM. 了解更多
  42. MSA-2

    Catalog No. A22139
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    non-nucleotide STING agonist
    MSA-2, a potent and orally available non-nucleotide STING agonist, is bound to STING as a noncovalent dimer with nanomolar affinity. 了解更多
  43. ASLAN003

    Catalog No. A22140
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    Dihydroorotate Dehydrogenase (DHODH) inhibitor
    ASLAN003 is an orally active and potent Dihydroorotate Dehydrogenase (DHODH) inhibitor with an IC50 of 35 nM for human DHODH enzyme. 了解更多
  44. (Rac)-JBJ-04-125-02

    Catalog No. A22141
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    EGFR inhibitor
    (Rac)-JBJ-04-125-02 is the racemate of JBJ-04-125-02. JBJ-04-125-02 is a potent, mutant-selective, allosteric and orally active EGFR inhibitor with an IC50 of 0.26 nM for EGFRL858R/T790M. 了解更多
  45. Takeda103A

    Catalog No. A22142
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    bovine tubulin oxidation inhibitor
    Takeda103A is a potent GRK2-dependent bovine tubulin oxidation inhibitor. 了解更多
  46. GSK199

    Catalog No. A22143
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    inhibitor of PAD4
    GSK199 is a selective inhibitor of PAD4 with IC50 of 200 nM in the absence of calcium. 了解更多
  47. Pyrimorph

    Catalog No. A22144
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    fungicide
    Pyrimorph is a fungicide with high activity against the plant pathogen Phytophthora capsici. 了解更多
  48. Soporidine

    Catalog No. A22145
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    strigolactone (SL) antagonist
    Soporidine is a strigolactone (SL) antagonist and inhibitor of germination in their biological assays. It binds AtHTL and specifically interferes with SL signaling. 了解更多
  49. GNE-140 racemic

    Catalog No. A22146
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    lactate dehydrogenase (LDHA) inhibitor
    GNE-140 racemic is a novel potent lactate dehydrogenase (LDHA) inhibitor. 了解更多
  50. AA41612

    Catalog No. A22147
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    antagonist of melanopsin-mediated phototransduction
    AA41612 is an antagonist of melanopsin-mediated phototransduction. 了解更多

产品 51 到 100 共 3389个

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页面:
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  2. 2
  3. 3
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