“Tutalthromycin second gen”的搜索结果

产品 301 到 350 共 1633个

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  1. ODM-204

    Catalog No. A20025
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    androgen receptor/CYP17A1 dual inhibitor
    ODM-204 is novel nonsteroidal dual inhibitor of both androgen receptor and CYP17A1 enzyme, with IC50s of 80?nM and 22 nM, respectively. 了解更多
  2. ML-290

    Catalog No. A20008
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    RXFP1 agonist
    ML-290 is a first-in-class and potent relaxin/insulin-like family peptide receptor (RXFP1) agonist and activator of anti-fibrotic genes, with an EC50 of 94 nM. 了解更多
  3. LMP7-IN-1

    Catalog No. A19995
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    LMP7 inhibitor
    LMP7-IN-1 is an inhibitor of immunoproteasome (LMP7), may used in the research of inflammatory and autoimmune diseases, neurodegenerative diseases, proliferative diseases and cancer. 了解更多
  4. DT-061

    Catalog No. A19989
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    PP2A activator
    DT-061 is an orally bioavailable activator of protein phosphatase 2A (PP2A) and could be applied in the therapy of KRAS-mutant and MYC-driven tumorigenesis. 了解更多
  5. D4-abiraterone

    Catalog No. A19987
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    androgen receptor antagonist
    D4-abiraterone is a major metabolite of abiraterone. D4-abiraterone is an inhibitor of CYP17A1, 3b-hydroxysteroid dehydrogenase (3βHSD) and steroid-5a-reductase (SRD5A) and also an antagonist of androgen receptor. 了解更多
  6. Reproxalap

    Catalog No. A19978
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    RASP sequestering agent
    Reproxalap (ADX-102) is a reactive aldehyde species (RASP) sequestering agent for the treatment of dry eye. Reproxalap (ADX-102) covalently binds aldehydes including malondialdehyde and 4-hydroxynonenal. 了解更多
  7. HO-1-IN-1

    Catalog No. A19975
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    HO-1 inhibitor
    HO-1-IN-1 (Compound 2) is a heme oxygenase 1 (HO-1) inhibitor with an IC50 of 250 nM. 了解更多
  8. A 1070722

    Catalog No. A19973
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    GSK-3 inhibitor
    A 1070722 is a potent and selective glycogen synthase kinase 3 (GSK-3) inhibitor, with a Ki of 0.6 nM for both GSK-3α and GSK-3β. 了解更多
  9. NucPE1

    Catalog No. A19964
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    NucPE1 (Nuclear Peroxy Emerald 1) is a nuclear-localized fluorescent hydrogen peroxide that is specifically localized to cellular nuclei without appended targeting moieties. 了解更多
  10. N-Nonyldeoxynojirimycin

    Catalog No. A19963
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    alpha-glucosidase/alpha-1,6-glucosidase inhibitor
    N-Nonyldeoxynojirimycin (NN-DNJ) is a potent inhibitor of alpha-glucosidase and alpha-1,6-glucosidase (IC50s, 0.42, 8.4 μM, respectively), inhibits glycogen breakdown. 了解更多
  11. PD-118057

    Catalog No. A19962
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    hERG channel activator
    PD-118057 is a human ether-a-go-go-related gene (hERG) channel activator that does not cause hERG blockade. 了解更多
  12. H3B-5942

    Catalog No. A19960
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    estrogen receptor covalent antagonist
    H3B-5942 is a selective, irreversible and orally active estrogen receptor covalent antagonist, inactivates both wild-type and mutant ERα by targeting Cys530, with Kis of 1 nM and 0.41 nM, respectively. 了解更多
  13. Oleoylethanolamide

    Catalog No. A19944
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    PPAR-α agonist
    Oleoylethanolamide is a high affinity endogenous PPAR-α agonist, which plays an important role in the treatment of obesity and arteriosclerosis. 了解更多
  14. Kanosamine hydrochloride

    Catalog No. A19932
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    Kanosamine hydrochloride is an antibiotic which inhibits the growth of plant-pathogenic oomycetes, certain fungi and a few bacterial species. Kanosamine inhibits Phytophthora medicaginis M2913 and Aphanomyces euteiches WI-98 with MICs of 25 and 60 ?g/mL, respectively. 了解更多
  15. 18:0 LYSO-PE

    Catalog No. A19930
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    18:0 LYSO-PE is an agent that can induce [Ca2+]i increase. 了解更多
  16. GSK180

    Catalog No. A19923
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    KMO inhibitor
    GSK180 is a selective, competitive, and potent inhibitor of kynurenine-3-monooxygenase (KMO), a key enzyme of tryptophan metabolism (IC50, ~6 nM), but shows negligible activity against other enzymes on the tryptophan pathway. 了解更多
  17. NAI-N3

    Catalog No. A19911
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    RNA acylation reagent
    NAI-N3 is a novel RNA acylation reagent that enables RNA purification. 了解更多
  18. Leelamine hydrochloride

    Catalog No. A19910
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    CB1 agonist
    Leelamine hydrochloride is a tricyclic diterpene molecule that is extracted from the bark of pine trees. Leelamine hydrochloride is a cannabinoid receptor type 1 (CB1) agonist and a inhibitor of SREBP1-regulated fatty acid/lipid synthesis in prostate cancer cells that is not affected by androgen receptor status. 了解更多
  19. Auxinole

    Catalog No. A19909
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    TIR1/AFB receptors auxin antagonist
    Auxinole is a potent auxin antagonist of TIR1/AFB receptors, binding TIR1 to block the formation of the TIR1-IAA-Aux/IAA complex and so inhibits auxin-responsive gene expression. 了解更多
  20. CAY 10465

    Catalog No. A19869
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    AhR agonist
    CAY 10465 is a selective and high-affinity AhR agonist, with a Ki of 0.2 nM, and shows no effect on estrogen receptor (Ki >100000 nM). 了解更多
  21. L-368,899 hydrochloride

    Catalog No. A19843
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    oxytocin receptor antagonist
    L-368,899 hydrochloride is a potent, selective, orally bioavailable, non-peptide oxytocin receptor antagonist, with IC50s of 8.9 nM and 26 nM for rat uterus and human uterus oxytocin receptor, respectively, used as a tocolytic agent. 了解更多
  22. ADHP

    Catalog No. A19826
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    fluorogenic peroxidase substrate
    ADHP is a fluorogenic peroxidase substrate (λex=530 nm, λem=590 nm). 了解更多
  23. Guggulsterone

    Catalog No. A19825
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    Guggulsterone is a plant sterol derived from the gum resin of the tree Commiphora wightii. Guggulsterone inhibits the growth of a wide variety of tumor cells and induces apoptosis through down regulation of antiapoptotic gene products (IAP1, xIAP, Bfl-1/A1, Bcl-2, cFLIP and survivin), modulation of cell cycle proteins (cyclin D1 and c-Myc), activation of caspases and JNK, inhibition of Akt. 了解更多
  24. BAY-2402234

    Catalog No. A19822
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    DHODH inhibitor
    BAY-2402234 is a selective dihydroorotate dehydrogenase (DHODH) inhibitor for the treatment of myeloid malignancies. 了解更多
  25. Siltenzepine

    Catalog No. A19818
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    Siltenzepine is an anti-acid agent. It is used in the treatment of peptic ulcers. 了解更多
  26. BCECF

    Catalog No. A19817
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    fluorescent agent
    Cardiogreen is fluorescent agent with low toxicity has been widely used in medical diagnostics. 了解更多
  27. GCN2iB

    Catalog No. A19806
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    GCN2 inhibitor
    GCN2iB is an ATP-competitive inhibitor of a serine/threonine-protein kinase general control nonderepressible 2 (GCN2), with an IC50 of 2.4 nM. 了解更多
  28. Duocarmycin MB

    Catalog No. A19799
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    ADCs toxin
    Duocarmycin MB is an antibody drug conjugates (ADCs) toxin. Duocarmycin is a DNA alkylating agent that binds in the minor groove. Duocarmycin MB can be used against multi-drug resistant cell lines. 了解更多
  29. Xanthorrhizol

    Catalog No. A19796
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    Xanthorrhizol, isolated from Curcuma xanthorrhiza Roxb, is a potential antibacterial agent. 了解更多
  30. ACP-105

    Catalog No. A19778
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    androgen receptor modulator
    ACP-105 is an orally available, selective amd potent androgen receptor modulator (SARM), with pEC50s of 9.0 and 9.3 for AR wild type and T877A mutant, respectively. 了解更多
  31. Diethyl-pythiDC

    Catalog No. A19766
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    CP4Hs inhibitor
    Diethyl-pythiDC is an inhibitor of collagen prolyl 4-hydroxylases (CP4Hs). 了解更多
  32. GSK656

    Catalog No. A19761
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    GSK656 is a potent antitubercular agent, acting as an inhibitor of Mycobacterium tuberculosis (Mtb) leucyl-tRNA synthetase (LeuRS), with an IC50 of 0.2 μM. 了解更多
  33. Dabsyl chloride

    Catalog No. A19755
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    amine derivatizing agent
    Dabsyl chloride is an amine derivatizing agent, able to give rise to stable products that can be easily monitored spectrophotometrically at 460 nm; Dabsyl chloride also used for labeling amino acids. 了解更多
  34. GDC-0927

    Catalog No. A19747
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    estrogen receptor antagonist
    GDC-0927 (SRN-927) is a novel, potent, non-steroidal, orally bioavailable, selective estrogen receptor antagonist. 了解更多
  35. Estrone-N-O-C1-amido

    Catalog No. A19746
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    estrogen ligand
    Estrone-N-O-C1-amido (ERα ligand 1) is an Estrone-based estrogen ligand, which targets estrogen receptor α (ERα). Estrone-N-O-C1-amido (ERα ligand 1) binds to cIAP1 ligand Bestatin via a linker to form SNIPER. 了解更多
  36. LSZ-102

    Catalog No. A19728
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    estrogen receptor degrader
    LSZ-102 is a potent, orally bioavailable selective estrogen receptor degrader with an IC50 of 0.2 nM. 了解更多
  37. N-(2-Chloro-6-methylphenyl)-N'-4-pyridinylurea

    Catalog No. A19727
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    N-[(1R)-4-[(Aminoiminomethyl)amino]-1-[[[(1R)-1-(4-hydroxyphenyl)ethyl]amino]carbonyl]butyl]-α-phenylbenzeneacetamide is an anticonvulsant agent with potential for the treatment of generalized tonic-clonic and partial seizures. 了解更多
  38. N-Acetylcysteine amide

    Catalog No. A19719
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    N-Acetylcysteine amide is a cell membranes and blood brain barrier permeant thiol antioxidant and neuroprotective agent, reduces ROS production. 了解更多
  39. Fluorescein di(β-D-galactopyranoside)

    Catalog No. A19707
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    β-galactosidase fluorogenic substrate
    Fluorescein di(β-D-galactopyranoside) is a fluorogenic substrate for β-galactosidase (λex=485 nm, λem=535 nm). 了解更多
  40. 5-Methoxyflavone

    Catalog No. A19698
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    DNA polymerase-beta inhibitor
    5-Methoxyflavone, belonged to Flavonoid family, is a DNA polymerase-beta inhibitor and neuroprotective agent against beta-amyloid toxicity. 了解更多
  41. PROTAC ERα Degrader-2

    Catalog No. A19697
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    ERα degrader
    PROTAC ERα Degrader-2 comprises a cIAP1 ligand binding group, a linker and an estrogen receptor α (ERα) binding group. PROTAC ERα Degrader-2 is an ERα degrader. 了解更多
  42. RO-7

    Catalog No. A19695
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    PA endonuclease inhibitor
    RO-7 is a next-generation polymerase (PA) endonuclease inhibitor of influenza A and B viruses. 了解更多
  43. Androstanolone acetate

    Catalog No. A19688
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    androgen ligand
    Androstanolone acetate is an androgen ligand, which targets androgen receptor (AR). Androstanolone acetate binds to cIAP1 ligand Bestatin via a linker to form PROTACs. 了解更多
  44. R162

    Catalog No. A19685
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    GLUD1 inhibitor
    R162 is a potent inhibitor of glutamate dehydrogenase 1 (GDH1/GLUD1), with anti-cancer properties. 了解更多
  45. RGX-104

    Catalog No. A19682
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    LXR agonist
    RGX-104 is a small-molecule LXR agonist that modulates innate immunity via transcriptional activation of the ApoE gene. 了解更多
  46. PROTAC AR Degrader-4

    Catalog No. A19678
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    AR degrader
    PROTAC AR Degrader-4 comprises a cIAP1 ligand binding group, a linker and an androgen receptor (AR) binding group. PROTAC AR Degrader-4 is an AR degrader. 了解更多
  47. Beryllon II

    Catalog No. A19677
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    chromogenic reagent
    Beryllon II is a widely used chromogenic reagent that is used to determine many elements, such as Mo, Mg and Co, and also used for the determination of proteins. 了解更多
  48. NCT-505

    Catalog No. A19669
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    ALDH1A1 inhibitor
    NCT-505 is a potent and selective aldehyde dehydrogenase (ALDH1A1) inhibitor, with an IC50 of 7 nM, and weakly inhibits hALDH1A2, hALDH1A3, hALDH2, hALDH3A1 (IC50s, >57, 22.8, 20.1, >57 μM). 了解更多
  49. 4-Hydroxychalcone

    Catalog No. A19662
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    4-Hydroxychalcone is a chalcone metabolite with anti-angiogenic and anti-inflammatory activities. 了解更多
  50. NCT-506

    Catalog No. A19660
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    ALDH1A1 inhibitors
    NCT-506 is an orally bioavailable aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitors with an IC50 of 7 nM. 了解更多

产品 301 到 350 共 1633个

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