P2X Receptor

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  1. A 438079 hydrochloride

    Catalog No. A14983
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    P2X7 receptor 拮抗剂
    A 438079 hydrochloride是一种竞争性P2X7受体拮抗剂(抑制人重组P2X7细胞系中Ca2+流入的pIC50 = 6.9)。 了解更多
  2. AF-353

    Catalog No. A13131
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    P2X3/P2X2/3 receptor 拮抗剂
    AF-353是一种新型、有效的P2X3/P2X2/3受体拮抗剂,可抑制人和大鼠的P2X3(pIC50 = 8.0)。 了解更多
  3. JNJ-54175446

    Catalog No. A18675
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    P2X7 receptor antagonist
    JNJ-54175446 is a potent and selective brain penetrant P2X7 receptor antagonist, with pIC50s of 8.46 and 8.81 for hP2X7 receptor and rP2X7 receptor, respectively. 了解更多
  4. A 839977

    Catalog No. A21178
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    P2X7 selective antagonist
    A 839977 is a P2X7 selective antagonist. 了解更多
  5. CE-224535

    Catalog No. A21183
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    P2X7 receptor antagonist
    CE-224535 is a selective P2X7 receptor antagonist. 了解更多
  6. GW791343 trihydrochloride

    Catalog No. A21204
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    P2X7 allosteric modulator
    GW791343 3Hcl is a P2X7 allosteric modulator; exhibits species-specific activity and acts as a negative allosteric modulator of human P2X7 (pIC50 = 6.9 - 7.2). 了解更多
  7. Minodronic acid

    Catalog No. A21975
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    purinergic P2X2/3 receptors antagonist
    Minodronic acid (YM-529) is an antagonist of purinergic P2X2/3 receptors involved in pain. 了解更多
  8. GW791343 HCl

    Catalog No. A11107
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    P2X7 modulator
    GW791343 HCl充当人P2X7的负变构调节剂(pIC50 = 6.9-7.2)和大鼠P2X7的正变构调节剂。 了解更多
  9. Ticlopidine HCl

    Catalog No. A11690
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    Ticlopidine是一种二磷酸腺苷(ADP)受体抑制剂。它通过阻断ADP受体来改变血小板膜的功能,从而抑制血小板聚集。这防止了糖蛋白IIb/IIIa的构象变化,从而使血小板与血纤蛋白原结合。 了解更多
  10. A 740003

    Catalog No. A11316
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    P2X7 receptor 拮抗剂
    A740003是P2X7受体的新型竞争性拮抗剂(人的IC50值= 40 nM,大鼠的IC50值= 18 nM)。 了解更多
  11. NF 279

    Catalog No. A11972
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    P2X1 拮抗剂
    NF279是一种苏拉明类似物,可作为P2X受体的高选择性,竞争性和可逆性ATP拮抗剂(平滑肌中IC50/KB1μM)。 了解更多
  12. A-317491 sodium salt hydrate

    Catalog No. A12412
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    P2X3 and P2X2/3 receptor 拮抗剂
    A-317491 sodium salt hydrate是一种非核苷酸的P2X3和P2X2/3受体拮抗剂,可抑制受体介导的钙通量。 了解更多
  13. A-804598

    Catalog No. A16066
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    P2X7 receptor 拮抗剂
    A-804598是一种P2X7选择性竞争性拮抗剂,对人,大鼠和小鼠通道的IC50值分别为11、10和9 nM。 了解更多
  14. A-438079 HCl

    Catalog No. A12597
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    P2X7 receptor 拮抗剂
    A-438079 HCl是一种竞争性P2X7受体拮抗剂(抑制人重组P2X7细胞系中Ca2+流入的pIC50 = 6.9)。在其他P2受体上没有活性(IC50 > 10 uM)。 了解更多

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