Angiogenesis

Angiogenesis is the formation and remodelling of new blood vessels and capillaries from growth of pre-existing blood vessels. It normally occurs during wound healing and embryonic development, but is also required for tumour growth and metastasis in cancer.

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  1. PF 431396

    Catalog No. A11142
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    FAK/PYK2 抑制剂
    PF 431396是一种双粘着斑激酶(FAK)和富含脯氨酸的酪氨酸激酶2(PYK2)抑制剂(IC50值分别为2和11 nM)。 了解更多
  2. PF-00562271

    Catalog No. A12580
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    FAK 抑制剂
    PF-00562271是PF-562271的苯磺酸盐,是一种有效的,ATP竞争性,可逆的FAK和Pyk2抑制剂,IC50分别为1.5 nM和14 nM。 了解更多
  3. PF-4618433

    Catalog No. A13461
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    PYK2/FAK 抑制剂
    PF-4618433与原型BIRB796相比,PF-4618433显示出PYK2效价提高、p38活性降低和总体选择性优越。 了解更多
  4. NVP-TAE 226

    Catalog No. A11507
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    FAK 抑制剂
    NVP-TAE 226是一种强效FAK抑制剂,IC50为5.5 nM,对pyk2(IC50=3.5 nM)有适度的强效作用;对InsR, IGF-1R, ALK和c-Met的效力降低10-100倍。 了解更多

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