“AZ 960”的搜索结果

26 个项目

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  1. Anandamide

    Catalog No. A21835
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    immune modulator
    Anandamide is an immune modulator in the central nervous system acts via not only cannabinoid receptors (CB1 and CB2) but also other targets (e.g., GPR18/GPR55). 了解更多
  2. Pipendoxifene hydrochloride

    Catalog No. A21623
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    estrogen receptor modulators
    Pipendoxifene hydrochloride is a selective estrogen receptor modulators (SERMs). 了解更多
  3. Basmisanil

    Catalog No. A21321
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    GABAAα5 modulator
    Basmisanil is a highly selective GABAAα5 negative allosteric modulator. 了解更多
  4. AZD8797

    Catalog No. A21230
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    human CX3CR1 receptor modulator
    AZD8797 is an allosteric non-competitive and orally active modulator of the human CX3CR1 receptor; antagonizes CX3CR1 and CXCR2 with Kis of 3.9 and 2800 nM, respectively. 了解更多
  5. GW791343 trihydrochloride

    Catalog No. A21204
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    P2X7 allosteric modulator
    GW791343 3Hcl is a P2X7 allosteric modulator; exhibits species-specific activity and acts as a negative allosteric modulator of human P2X7 (pIC50 = 6.9 - 7.2). 了解更多
  6. PF-4778574

    Catalog No. A21157
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    AMPA receptor positive allosteric modulator
    PF-4778574 is a potent AMPA receptor positive allosteric modulator (PAM) that has been shown to enhance cognition in animal models. 了解更多
  7. IRAK inhibitor 3

    Catalog No. A11457
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    IL-1 receptor-associated kinase (IRAK) kinase modulator
    IRAK inhibitor 3 is an interleukin-1 (IL-I) receptor-associated kinase (IRAK) kinase modulator extracted from patent WO2008030579 A2. 了解更多
  8. TOK-8801

    Catalog No. A12288
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    immunomodulator
    TOK-8801 is a synthesized dihydroimidazothiazole carboxamide and is under development as an immunomodulator. 了解更多
  9. Endothelin Mordulator 1

    Catalog No. A13040
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    endothelin receptor modulator
    Endothelin Mordulator 1 is a endothelin receptor modulator, used for the research of endothelin-mediated disorders. 了解更多
  10. VU6001376

    Catalog No. A13763
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    metabotropic glutamate receptor 4 modulator
    VU6001376 is a potent and selective positive allosteric modulator of the metabotropic glutamate receptor 4 (mGlu4 PAM) with an EC50 of 50.1 nM. 了解更多
  11. Levamisole hydrochloride

    Catalog No. A10525
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    anthelmintic and immunomodulator
    Levamisole hydrochloride is an anthelmintic and immunomodulator belonging to a class of synthetic imidazothiazole derivatives. 了解更多
  12. GNE 0723

    Catalog No. A12757
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    NMDAR modulator
    GNE 0723 is a brain permeable positive allosteric modulator of NMDAR, with an EC50 of 21 nM for GluN2A, 7.4 and 6.2 μM for GluN2C and GluN2D, respectively. 了解更多
  13. Insulin levels modulator

    Catalog No. A13315
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    Insulin levels modulator could be used to treat diabetes. 了解更多
  14. E1R

    Catalog No. A18825
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    sigma-1 receptors modulator
    E1R is a novel positive allosteric modulator of sigma-1 receptors. 了解更多
  15. Kv3 modulator 4

    Catalog No. A18951
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    Kv3.1/Kv3.2 modulator
    Kv3 modulator 4 is a Kv3.1 (pEC50=5.45) and Kv3.2 modulator extracted from patent WO2018020263A1, Cyclobutyl structure. 了解更多
  16. Kv3 modulator 3

    Catalog No. A18958
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    Kv3.1/Kv3.2/Kv3.3 channels modulator
    Kv3 modulator 3 (Compound 4) is a selective modulator of Kv3.1 and/or Kv3.2 and/or Kv3.3 channels extracted from patent WO2017098254A1, compound 4, has analgesic activity for use in the prophylaxis o or treatment of pain. 了解更多
  17. Kv3 modulator 2

    Catalog No. A18965
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    Kv3 channels modulator
    Kv3 modulator 2 (formula (I)) is a potent Kv3 channels modulator extracted from patent WO2018109484A1, compound formula (I) , has analgesic activity and is used in the prophylaxis or treatment of related disorders. 了解更多
  18. SBI-553

    Catalog No. A18435
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    NTR1 allosteric modulator
    SBI-553 is a potent and brain penetrant NTR1 allosteric modulator. 了解更多
  19. VU6005806

    Catalog No. A18488
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    M4 modulator
    VU6005806 (AZN-00016130) is a potent muscarnic acethylcholine receptor subtype 4 (M4) positive allosteric modulator (PAM), with EC50s of 94 nM, 28 nM, 87 nM and 68 nM for human, rat, dog and cyno M4, respectively. Used in the research of neuropsychiatric disorders. 了解更多
  20. AZD9567

    Catalog No. A18850
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    selective glucocorticoid receptor modulator
    AZD9567 is a potent, oral active, non-steroidal and selective glucocorticoid receptor modulator (SGRM), with an IC50 of 3.8 nM. 了解更多
  21. Rovazolac

    Catalog No. A18354
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    liver x receptor (LXR) modulator
    Rovazolac is a liver x receptor (LXR) modulator extracted from patent WO2013130892A1. 了解更多
    • 最新产品

    PUN30119

    Catalog No. A17232
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    PUN30119, also known as Imidazole ketone erastin (IKE), is a potent, metabolically stable inhibitor of system xc- and inducer of ferroptosis potentially suitable for in vivo applications. 了解更多
  22. Azoramide

    Catalog No. A16075
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    UPR modulator
    Azoramide是具有抗糖尿病活性的未折叠蛋白应答的小分子调节剂。 了解更多
  23. ISX-9

    Catalog No. A15774
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    Neurogenic Modulator
    ISX-9是成人神经干细胞分化的小分子诱导剂。 了解更多
  24. Bazedoxifene

    Catalog No. A15019
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    Estrogen modulator
    Bazedoxifene是雌激素受体的第三代选择性调节剂。 了解更多
  25. Vortioxetine (Lu AA21004) hydrobromide

    Catalog No. A12602
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    5-HT Receptor modulator
    Vortioxetine (Lu AA21004) hydrobromide是一种口服多峰血清素能药物,可抑制5-HT(1A),5-HT(1B),5-HT(3A),5-HT(7)和SERT,IC50为15 nM,33 nM,3.7 nM,19 nM和1.6 nM。 了解更多

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