“angiotensin converting enzyme ace”的搜索结果
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non-peptide angiotensin II receptor antagonist
Fimasartan is a non-peptide angiotensin II receptor antagonist (ARB) used for the treatment of hypertension and heart failure. Through oral administration, fimasartan blocks angiotensin II receptor type 1 (AT1 receptors), reducing pro-hypertensive actions of angiotensin II, such as systemic vasoconstriction and water retention by the kidneys.
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Angiotensin II receptor antagonist
Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.
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angiotensin II type 1 receptor antagonist
Azilsartan D5 is the deuterium labeled Azilsartan(TAK-536), which is a specific and potent angiotensin II type 1 receptor antagonist.
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angiotensin II receptor antagonist
Losartan D4 Carboxylic Acid is the deuterium labeled Losartan(EXP-3174), which is an angiotensin II receptor antagonist.
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angiotensin II and endothelin A receptor antagonist
Sparsentan (RE-021) is a highly potent dual angiotensin II and endothelin A receptor antagonist with Kis of 0.8 and 9.3 nM, respectively.
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angiotensin II receptor type 1 antagonist
Azilsartan medoxomil monopotassium is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension.
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angiotensin II receptor antagonist
Valsartan (CGP-48933) is an angiotensin II receptor antagonist for the treatment of high blood pressure and heart failure.
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Angiotensin AT1 receptor antagonist
SL910102 is a nonpeptide angiotensin AT1 receptor antagonist.
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angiotensin II receptor type 1 拮抗剂
Azilsartan medoxomil是一种口服给药的1型血管紧张素II受体拮抗剂,IC50为0.62 nM。
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angiotensin II receptor 拮抗剂
BIBS39是一种非肽血管紧张素II(AII)受体拮抗剂,可从其特异性结合位点置换[125I] AII,其AII亚型(AT1)受体和K(i)的K(i)值为29+/-7 nM。)AII亚型2(AT2)受体的480+/-110 nM)值。
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Angiotensin II receptor 拮抗剂
Tasosartan是一种血管紧张素II受体拮抗剂。
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angiotensin AT2 receptor 拮抗剂
PD 123319 ditrifluoroacetate是一种有效的,选择性的非肽血管紧张素AT2受体拮抗剂。大鼠肾上腺组织和大脑的IC50值分别为34和210 nM。
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- Dao-Lai Zhang, .et al. Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility, eLife, 2018, 7: e33432 PMID: 29393851
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GnRH antagonist
Cetrorelix acetate is a synthetic decapeptide with gonadotropin-releasing hormone (GnRH) antagonistic activity used in infertility treatment. The IC50 of 1.21 nM.
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GnRH 拮抗剂
Degarelix acetate是促性腺激素释放激素(GnRH)受体拮抗剂。
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GnRH 拮抗剂
Abarelix acetate是一种合成的肽促性腺激素释放激素受体(GnRH)拮抗剂。
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Androgen Receptor 拮抗剂
Cyproterone acetate是17-羟孕酮的合成衍生物,可作为雄激素受体拮抗剂以及具有弱孕激素和糖皮质激素活性的弱孕激素受体激动剂。
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