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搜索结果：“263”

“263”的搜索结果

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MK-3697

Catalog No. A12633
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OX2 拮抗剂

MK-3697是一种高效的，口服生物利用的选择性orexin 2受体拮抗剂，Ki值为0.95nM。了解更多

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Endoxifen

Catalog No. A12639
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Estrogen receptor 拮抗剂

Endoxifen是他莫昔芬的次生代谢产物。它是负责他莫昔芬在ER阳性乳腺癌中有效性的主要代谢物。Endoxifen Z-isomer抑制hERG, 这种作用具有浓度依赖性, IC50值为1.6μM。了解更多

Product Citations (2)

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- Marina Arino Martin, .et al. Photolytic fate of (E)- and (Z)-endoxifen in water and treated wastewater exposed to sunlight, Environ Res, 2021, Apr 3;197:111121 PMID: 33823193
- Martin MA, .et al. Photodegradation of (E)- and (Z)-Endoxifen in water by ultraviolet light: Efficiency, kinetics, by-products, and toxicity assessment, Water Res, 2019, Dec 29;171:115451 PMID: 31901682
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DL-AP3

Catalog No. A15378
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mGluR1 拮抗剂

DL-AP3是D-AP3和L-AP3的外消旋制剂，是磷酸丝氨酸磷酸酶的抑制剂和代谢型谷氨酸受体（mGluR）的拮抗剂，阻断了由mGluR介导的磷酸肌醇转换。了解更多

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7-Chlorokynurenic acid sodium salt

Catalog No. A21879
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NMDA receptor antagonist

7-Chlorokynurenic acid sodium salt is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor (IC50=0.56 μM). 了解更多

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MRT-83

Catalog No. A21020
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Smo antagonist

MRT-83 is a potent antagonist of Smo, with an IC50 in the nanomolar range. MRT-83 also blocks Hedgehog (Hh) signaling. 了解更多

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Philanthotoxin 74 dihydrochloride

Catalog No. A21739
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AMPAR antagonist

Philanthotoxin 74 dihydrochloride (PhTx 74) is an AMPAR antagonist; inhibits GluR3 and GluR1 with IC50s of 263 and 296 nM, respectively. 了解更多

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