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Talazoparib tosylate

Catalog No. A20238
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PARP1/2 inhibitor

Talazoparib tosylate (BMN 673ts) is a novel, potent and orally available PARP1/2 inhibitor with an IC50 of 0.57 nM for PARP1. 了解更多

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GeA-69

Catalog No. A19705
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PARP14 inhibitor

GeA-69 is a selective, highly cell permeable allosteric inhibitor of poly-adenosine-diphosphate-ribose polymerase 14 (PARP14) targeting macrodomain 2, with a Kd of 2.1 ?M. 了解更多

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NMS-P118

Catalog No. A20994
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PARP-1 Inhibitor

NMS-P118 is a potent, orally available, and highly selective PARP-1 Inhibitor for cancer therapy. 了解更多

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Niraparib hydrochloride

Catalog No. A18018
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PARP1 and PARP2 inhibitor

Niraparib hydrochloride (MK-4827 hydrochloride) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively. 了解更多

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Niraparib tosylate

Catalog No. A16618
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PARP1/PARP2 inhibitor

Niraparib tosylate (MK-4827 tosylate) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with an IC50 of 3.8 and 2.1 nM, respectively. 了解更多

Product Citations (1)

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- Laurie B Schenkel, .et al. A potent and selective PARP14 inhibitor decreases protumor macrophage gene expression and elicits inflammatory responses in tumor explants, Cell Chem Biol, 2021, Mar 2;S2451-9456(21)00095-7 PMID: 33705687