“rasgap ras p21”的搜索结果

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  1. (±)-Huperzine A

    Catalog No. A21003
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    AChE inhibitor
    (??)-Huperzine A, an active Lycopodium alkaloid extracted from traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the treatment of Alzheimer's disease (AD). 了解更多
  2. (+)-Phenserine

    Catalog No. A20993
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    cholinesterase noncompetitive inhibitor
    (+)-Phenserine is a novel selective cholinesterase noncompetitive inhibitor with an IC50 of 45.3 μM. 了解更多
  3. (R)-Rivastigmine D6 tartrate

    Catalog No. A21454
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    cholinesterase inhibitor
    (R)-Rivastigmine D6 (tartrate) is the deuterium labeled (R)-Rivastigmine, which is an cholinesterase inhibitor. 了解更多
  4. Eicosatetraynoic acid

    Catalog No. A19008
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    COX/LOX inhibitor
    Eicosatetraynoic acid (ETYA) is a nonspecific inhibitor of cyclooxygenase and lipoxygenase (ID50=8 μM and 4 μM, respectively). Eicosatetraynoic acid (ETYA) activates PPARα and PPARγ chimeras at 10 ?M?? 了解更多
  5. Acetyllovastatin

    Catalog No. A19111
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    AChE inhibitor
    Acetyllovastatin, a acetate of Lovastatin, presentes a moderate inhibitory effect against the enzyme acetylcholinesterase with an IC50 of 79 μg/mL. Lovastatin has been found to display antifungal activity, and suppresses proliferation of a number of transformed cell lines. 了解更多
  6. MHP 133

    Catalog No. A20058
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    AChE /M1/M2/5HT4/I2 inhibitor
    MHP 133 is a drug with multiple CNS targets, and inhibits acetylcholinesterase (AChE) with Ki of 69 μM; also active against muscarinic M1 and M2 receptors, serotonin 5HT4 receptors, and imidazole I2 receptors. 了解更多
  7. Galanthamine

    Catalog No. A12483
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    AChE inhibitor
    Galanthamine is a potent acetylcholinesterase (AChE) inhibitor with an IC50 of 500 nM. 了解更多
  8. Baclofen

    Catalog No. A18248
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    GABA agonist
    Baclofen is a GABA agonist specific for GABA-B receptors. Baclofen is a synthetic chlorophenyl-butanoic acid derivative used to treat spasms due to spinal cord damage and multiple sclerosis, muscle-relaxing It acts at spinal and supraspinal sites, reducing excitatory transmission. 了解更多
  9. Cevimeline hydrochloride

    Catalog No. A18092
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    mAChR agonist
    Cevimeline (Evoxac) Hcl is a parasympathomimetic and muscarinic agonist, with particular effect on M3 receptors; used in the treatment of dry mouth associated with sjogren's syndrome. 了解更多
  10. Cangrelor Tetrasodium

    Catalog No. A17919
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    P2Y12 receptors inhibitor
    Cangrelor Tetrasodium is a high-affinity, reversible inhibitor of P2Y12 receptors that causes almost complete inhibition of ADP-induced platelet aggregate. It is a modified ATP derivative stable to enzymatic degradation. Unlike clopidogrel (Plavix), which is a prodrug, cangrelor is an active drug not requiring metabolic conversion. 了解更多
  11. Edrophonium chloride

    Catalog No. A17794
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    acetylcholinesterase inhibitor
    Edrophonium Chloride, also known as Tensilon, is an acetylcholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. Edrophonium Chloride has also been used as an antidote to curare principles. 了解更多
  12. Pralidoxime Iodide

    Catalog No. A17526
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    Cholinesterase Reactivator
    Pralidoxime iodide is a Cholinesterase Reactivator. 了解更多
  13. Tacrine HCl

    Catalog No. A17374
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    AChE & butyrylcholinesterase inhibitor
    Tacrine is a derivative of aminoacridine that functions as an inhibitor of both acetylcholinesterase (AChE) and butyrylcholinesterase (IC50s = 31 and 26.5 nM, respectively). 了解更多
  14. Prasugrel Hydrochloride

    Catalog No. A16144
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    P2Y12 拮抗剂
    Prasugrel Hydrochloride是噻吩并吡啶ADP受体(P2Y12)拮抗剂,用于减少血栓性心血管事件。 了解更多
  15. NVP-AAM077 Tetrasodium Hydrate (PEAQX)

    Catalog No. A14071
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    NMDA receptors 拮抗剂
    NVP-AAM077抑制成年小鼠在脑室下区域和齿状回中的祖细胞增殖,并降低了齿状回中的新生细胞的存活。 了解更多
  16. Donepezil hydrochloride

    Catalog No. A10330
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    cholinesterase 抑制剂
    Donepezil hydrochloride是一种中枢可逆的乙酰胆碱酯酶抑制剂。 了解更多
  17. Prasugrel (Effient)

    Catalog No. A10748
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    platelet inhibitor
    Prasugrel (Effient)是一种新型的血小板抑制剂,用于减少急性冠脉综合征(PCI)患者的血栓性心血管事件(包括支架血栓形成)。 了解更多

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