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  1. Ralfinamide mesylate

    Catalog No. A22002
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    Na+ channel blocker
    Ralfinamide mesylate (FCE-26742A mesylate) is an orally available Na+ channel blocker derived from α-aminoamide, with function of suppressing pain. 了解更多
  2. Naspm

    Catalog No. A21919
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    AMPA (CP-AMPA) receptors antagonist
    Naspm (1-Naphthyl acetyl spermine), a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist. 了解更多
  3. A-1165442

    Catalog No. A21516
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    TRPV1 antagonist
    A-1165442 is a potent, competitive and orally available TRPV1 antagonist with an IC50 of 9 nM for human TRPV1. 了解更多
  4. Naspm trihydrochloride

    Catalog No. A21437
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    CP-AMPA receptors antagonist
    Naspm trihydrochloride (1-Naphthylacetyl spermine trihydrochloride), a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist. 了解更多
  5. Ivacaftor hydrate

    Catalog No. A15133
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    CFTR potentiator
    Ivacaftor hydrate is an orally bioavailable CFTR potentiator, used for cystic fibrosis treatment. 了解更多
  6. Ivacaftor benzenesulfonate

    Catalog No. A15132
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    CFTR potentiator
    Ivacaftor benzenesulfonate is an orally bioavailable CFTR potentiator, used for cystic fibrosis treatment. 了解更多
  7. Nav1.7-IN-3

    Catalog No. A13626
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    voltage-gated sodium channel Nav1.7 inhibitor
    Nav1.7-IN-3 is a selective, orally bioavailable voltage-gated sodium channel Nav1.7 inhibitor with an IC50 of 8 nM. Pain relief. Limited CNS penetration. 了解更多
  8. Pico145

    Catalog No. A13344
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    TRPC1/4/5 channels inhibitor
    Pico145 is a remarkable inhibitor of TRPC1/4/5 channels, inhibits (?)-englerin A-activated TRPC4/TRPC5 channels, with IC50s of 0.349 and 1.3 nM in cells, and shows no effect on TRPC3, TRPC6, TRPV1, TRPV4, TRPA1, TRPM2, TRPM8. 了解更多
  9. AMG2850

    Catalog No. A19445
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    TRPM8 antagonist
    AMG2850 is a potent, orally bioavailable and selective transient receptor potential melastatin 8 (TRPM8) antagonist. 了解更多
  10. SGL5213

    Catalog No. A18723
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    SGLT1 抑制剂
    SGL5213 is a potent, oral active and low-absorbable sodium-dependent glucose cotransporter 1 (SGLT1) inhibitor, with IC50 values of 29 nM and 20 nM for hSGLT1 and hSGLT2, respectively. 了解更多
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    SAR-7334 HCl

    Catalog No. A17237
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    TRPC6 inhibitor
    SAR7334 is a novel, highly potent and bioavailable inhibitor of TRPC6 channels that opens new opportunities for the investigation of TRPC channel function in vivo. SAR7334 inhibited TRPC6, TRPC3 and TRPC7-mediated Ca(2+) influx into cells with IC50 s of 9.5, 282 and 226 nM, whereas TRPC4 and TRPC5-mediated Ca(2+) entry was not affected. 了解更多

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