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搜索结果：“ab fubinaca”

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Trametinib (DMSO solvate)

Catalog No. A21450
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MEK inhibitor

Trametinib DMSO solvate (GSK-1120212 (DMSO solvate);JTP-74057 (DMSO solvate)) is a potent MEK inhibitor that specifically inhibits MEK1/2, with an IC50 value of about 2 nM. 了解更多

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- Yuki Shimizu, .et al. Acquired resistance to BRAF inhibitors is mediated by BRAF splicing variants in BRAF V600E mutation-positive colorectal neuroendocrine carcinoma, Cancer Lett, 2022, Sep 1;543 PMID: 35724767
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Hypothemycin

Catalog No. A13750
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Hypothemycin是间苯二酸内酯聚酮。已发现抑制用抗CD3 mAb+ PMA刺激的小鼠和人T细胞以及仅用抗CD3 mAb刺激的人PBMC的增殖。了解更多

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TAK-733

Catalog No. A11040
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MEK 抑制剂

TAK-733是一种有效的，选择性的MEK变构抑制剂，作用于MEK1，IC50为3.2 nM，抑制Abl1，AKT3，c-RAF，CamK1，CDK2及c-Met等活性。了解更多

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