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￥ 0.00 “AG 013736”的搜索结果
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Motixafortide
Catalog No. A22276 CXCR4 antagonistMotixafortide (BKT140 4-fluorobenzoyl) is a novel CXCR4 antagonist with an IC50 vakue of ??1 nM. 了解更多 -
Ellagic acid (hydrate)
Catalog No. A22282 ATP-competitive CK2 inhibitorEllagic acid hydrate is a natural antioxidant, and acts as a potent and ATP-competitive CK2 inhibitor, with an IC50 of 40 nM and a Ki of 20 nM. 了解更多 -
Tomatidine hydrochloride
Catalog No. A22284 anti-inflammatory agentTomatidine hydrochloride acts as an anti-inflammatory agent by blocking NF-κB and JNK signaling. Tomatidine hydrochloride activates autophagy either in mammal cells or C elegans. 了解更多 -
Amarogentin
Catalog No. A22286 bitter taste receptor TAS2R1 agonistAmarogentin (AG), a secoiridoid glycoside mainly extracted from Swertia and Gentiana roots, exhibits anti-oxidative, anti-tumour, and anti-diabetic activities. Amarogentin is an agonist for the bitter taste receptor TAS2R1 and inhibits in LAD-2 cells substance P-induced production of newly synthesized TNF-α. 了解更多 -
Urolithin B
Catalog No. A22287 regulator of skeletal muscle massUrolithin B is one of the gut microbial metabolites of ellagitannins, and has anti-inflammatory and antioxidant effects. Urolithin B is also a regulator of skeletal muscle mass. 了解更多 -
3-Hydroxyanthranilic acid
Catalog No. A22292 immunomodulatory agent3-Hydroxyanthranilic Acid (3-HAA, 3-HANA), a tryptophan metabolite, has an immunomodulatory effect that may result from inhibition of PI3K/Akt/mTOR and NF-κB activity, thereby decreasing the production of pro-inflammatory mediators. 了解更多 -
Acetosyringone
Catalog No. A22294 anti-inflammatory agentAcetosyringone is a phenolic natural product with analgesic, antipyretic and anti-inflammatory actions. 了解更多 -
Dorzagliatin
Catalog No. A22297 GK activatorDorzagliatin (HMS5552), a dual-acting glucokinase (GK) activator, improves glycaemic control and pancreatic β-cell function in type 2 diabetes. 了解更多 -
Homosalate
Catalog No. A22302 chemical UV filterHomosalate is an organic compound used in some sunscreens, it is used as a chemical UV filter, protecting the skin from sun damage. 了解更多 -
BDTX-189
Catalog No. A22306 Anticancer agentBDTX-189 is a potent, orally active and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations, including EGFR/HER2 exon 20 insertion mutants. BDTX-189 shows KDs of 0.2, 0.76, 13 and 1.2 nM for EGFR, HER2, BLK and RIPK2, reapectively. Anticancer activity. 了解更多 -
Loureirin A
Catalog No. A22313 flavonoidLoureirin A is a flavonoid extracted from Dragon's Blood, can inhibit Akt phosphorylation, and has antiplatelet activity. 了解更多 -
Higenamine
Catalog No. A22315 β2-AR agonistHigenamine (Norcoclaurine), a β2-AR agonist, is a key component of the Chinese herb aconite root that prescribes for treating symptoms of heart failure in the oriental Asian countries. 了解更多 -
Decursinol angelate
Catalog No. A22340 cytotoxic and protein kinase C (PKC) activating agentDecursinol angelate, a cytotoxic and protein kinase C (PKC) activating agent from the root of Angelica gigas, possesses anti-tumor and anti-inflammatory activities. 了解更多 -
3'-Hydroxypterostilbene
Catalog No. A22341 natural pterostilbene analogue3'-Hydroxypterostilbene, a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells (IC50s of 9.0, 40.2, and 70.9 ?M for COLO 205, HCT-116, and HT-29 cells, respectively) by inducing apoptosis and autophagy. 了解更多 -
Dihydrocaffeic acid
Catalog No. A22344 Antioxidant agentDihydrocaffeic acid is a phenolic acid found in Gynura bicolor, reduces phosphorylation of MAPK p38 and prevent UVB-induced skin damage. Antioxidant potential and anti-inflammatory activity. 了解更多 -
Pyridoxine
Catalog No. A22350 antioxidant agentPyridoxine (Pyridoxol) is a pyridine derivative. Pyridoxine exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway. 了解更多 -
Nootkatone
Catalog No. A22352 neuroprotective agentNootkatone, a neuroprotective agent from Alpiniae Oxyphyllae Fructus, has antioxidant and anti-inflammatory effects. 了解更多 -
Timosaponin AIII
Catalog No. A22353 Inhibitor of U46619-induced Rat Platelet AggregationTimosaponin AIII is a potent Inhibitor of U46619-induced Rat Platelet Aggregation, Selectively Inhibiting TxA2-induced Platelet Activation, Preferably Suppressing TP-mediated Activation of Gq, not G12/13, Signaling Pathways. 了解更多 -
Beta-asarone
Catalog No. A22354 neuroprotection agentBeta-Asarone, found in certain plants such as Acorus and Asarum, could pass the blood-brain barrier and exerts neuroprotection effects. 了解更多 -
Coumarin-3-carboxylic Acid
Catalog No. A22355 antiproliferative agentCoumarin-3-carboxylic acid (2- Oxochromene-3-carboxylic acid) is an important initial compound for the synthesis of coumarins which are well known natural products for their diverse biological activities. Lanthanide complexes of Coumarin-3-carboxylic acid exhibit antiproliferative activity towards K-562 cell line. 了解更多 -
(2S,3R,4S)-4-Hydroxyisoleucine
Catalog No. A22356 anti-diabetes agent(2S,3R,4S)-4-Hydroxyisoleucine is an orally active compound isolated from Trigonella foenum-graecum, with anti-diabetes and anti-diabetic nephropathy activity. 了解更多 -
Solamargine
Catalog No. A22357 anticancer agentSolamargine, a derivative from the steroidal solasodine in Solanum species, exhibits anticancer activities in numerous types of cancer. Solamargine induces non-selective cytotoxicity and P-glycoprotein inhibition. 了解更多 -
3BDO
Catalog No. A22360 -
BMP signaling agonist sb4
Catalog No. A22362 BMP4 signaling agonistBMP signaling agonist sb4 is a potent benzoxazole bone morphogenetic protein 4 (BMP4) signaling agonist with a EC50 value of 74 nM, activates BMP signaling by stabilizing intracellular p-SMAD-1/5/9. 了解更多 -
Pemafibrate
Catalog No. A22201 PPAR alpha agonistPemafibrate, also known as (R)-K 13675, is a PPAR alpha agonist. 了解更多 -
Emedastine
Catalog No. A22158 histamine H1 receptor antagonistEmedastine is an orally active, selective and high affinity histamine H1 receptor antagonist with a Ki value of 1.3 nM. 了解更多 -
Molnupiravir
Catalog No. A22165 broad-spectrum antiviral activityMolnupiravir (EIDD-2801, MK-4482) is an orally bioavailable prodrug of the ribonucleoside analog β-d-N4-hydroxycytidine (NHC; EIDD-1931) with broad-spectrum antiviral activity against SARS-CoV-2, MERS-CoV, SARS-CoV, and the causative agent of COVID-19. 了解更多 -
Periplogenin
Catalog No. A22174 anti-psoriatic agentPeriplogenin is a naturally occurring furanocoumarin found in Angelica dahurica roots, with potent anti-psoriatic effects. Periplogenin induces adipocyte differentiation. 了解更多 -
6-Methoxydihydroavicine
Catalog No. A22177 antiplatelet activities6-Methoxydihydroavicine is an alkaloid isolated from Zanthoxylum integrifoliolum. 6-Methoxydihydroavicine has antiplatelet activities and inhibits AA-, collagen- and PAF-induced platelet aggregation in vitro. 了解更多 -
BIO-013077-01
Catalog No. A22185 antagonist of the TGFbeta family type I receptors, Alk5 and/or Alk4BIO-013077-01, Novel potent antagonist of the TGFbeta family type I receptors, Alk5 and/or Alk4. 了解更多 -
Cholesterol
Catalog No. A22211 endogenous estrogen-related receptor α (ERRα) agonistCholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist. 了解更多 -
Ticlopidine
Catalog No. A22216 inhibitor of platelet aggregationTiclopidine (Yuclid, Ticlopidinum, Ticlopidina) is an orally active inhibitor of platelet aggregation induced by adenosine diphosphate (ADP). 了解更多 -
ML-335
Catalog No. A22244 OPRM1(μ-opioid receptor)-OPRD1(δ-opioid receptor) heterodimerization agonistML335 (CYM 51010, CID-23723457) is an agonist for OPRM1(μ-opioid receptor)-OPRD1(δ-opioid receptor) heterodimerization with EC50 of 403 nM demonstrating selectivity over the individual OPRM1 and OPRD1 receptors and the serotonin HT5A receptor with EC50 of 14.9 μM, 1.1 μM, and >40 μM, respectively. 了解更多
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