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VU590 (hydrochloride)
Catalog No. A22612 inhibitor of KCNJ1KCNJ1 (Kir1.1, or renal outer medullary potassium channel) and KCNJ13 (Kir7.1) are inwardly rectifying two-transmembrane K+ channels. KCNJ1 has critical roles in kidney function, while KCNJ13 is important in the eye, kidney, and small intestine. VU590 is a small molecule inhibitor of KCNJ1 (IC50 = 294 nM) which also causes 70% inhibition of KCNJ13 at 10 ?M. It has no effect on the related channels KCNJ2 (Kir2.1) and KCNJ10 (Kir4.1) at a concentration of 10 ?M. 了解更多 -
Leteprinim
Catalog No. A22613 neurotrophic agentLeteprinim, also known as AIT-082 and SPI-205, is a neurotrophic agent potentially for the treatment of Alzheimer's disease, and spinal cord injury. 了解更多 -
Ro 19-4603
Catalog No. A22614 benzodiazepine receptor inverse agonistRo 19-4603 is a benzodiazepine receptor inverse agonist. 了解更多 -
Lidocaine N-ethyl bromide
Catalog No. A22615 blocker of fast Na+-dependent action potentials and voltage-dependentLidocaine N-ethyl bromide is a non-membrane-permeable blocker of fast Na+-dependent action potentials and voltage-dependent, non-inactivating Na+ conductance. 了解更多 -
Flutonidine
Catalog No. A22620 alpha2-Adrenergic receptor agonistFlutonidine is an alpha2-Adrenergic receptor agonist. 了解更多 -
Cetrorelix diacetate
Catalog No. A22622 GnRH receptor antagonistCetrorelix diacetate (SB-075 diacetate) is a potent gonadotropin-releasing hormone (GnRH) receptor antagonist with an IC50 of 1.21 nM. 了解更多 -
DNQX Disodium
Catalog No. A22623 non-NMDA receptor antagonistDNQX Disodium is a water-soluble form of selective non-NMDA receptor antagonist DNQX. 了解更多 -
Sipoglitazar
Catalog No. A22625 PPARγ agonistSipoglitazar, also known as TAK-654, is a PPARγ agonist potentially for the treatment of diabetes. 了解更多 -
Pentamethonium bromide
Catalog No. A22627 -
YM 298198 Hydrochloride
Catalog No. A22630 mGlu1 receptorsant agonistYM 298198 Hydrochloride is a non-competitive antagonist with high affinity and selectivity for mGlu1 receptors (Ki = 19 nM). 了解更多 -
Gabazine free base
Catalog No. A22634 GABA receptor antagonistGabazine free base is a specific GABA receptor antagonist. Does not affect GABA-transaminase or glutamate-decarboxylase activitites. 了解更多 -
Tracazolate
Catalog No. A22635 pyrazolopyridine anxiolyticTracazolate is a pyrazolopyridine anxiolytic known to interact with gamma-aminobutyric acid (GABA)(A) receptors, adenosine receptors, and phosphodiesterases. 了解更多 -
Tioxazafen
Catalog No. A22636 broad-spectrum seed treatment nematicideTioxazafen is a disubstituted oxadiazole and a broad-spectrum seed treatment nematicide. Tioxazafen is designed to provide consistent broad-spectrum control of nematodes in corn, soy, and cotton. 了解更多 -
Betahistine EP Impurity C
Catalog No. A22638 histamine H1 receptor agonist and H3 receptor antagonistBetahistine EP Impurity C (NSC19005) is an impurity of Betahistine. Betahistine is a potent, orally active and well-tolerated histamine H1 receptor agonist and H3 receptor antagonist used for the study of rheumatoid arthritis (RA). 了解更多 -
Methyl 13-cis-4-Oxoretinoate
Catalog No. A22639 -
Tizoxanide
Catalog No. A22643 anti-infective agentTizoxanide is the active metabolite of Nitazoxanide, which is a thiazolide anti-infective compound against anaerobic bacteria, protozoa, and a range of viruses. Tizoxanide has anti-HIV-1 activities. 了解更多 -
Multi-kinase inhibitor 1
Catalog No. A22645 multi-kinase inhibitorMulti-kinase inhibitor 1 is a potent multi-kinase inhibitor. Multi-kinase inhibitor 1 has the potential for diseases or disorders associated with abnormal or deregulated tyrosine kinase activity, particularly diseases associated with the activity of PDGF-R, c-Kit and Bcr-abl. 了解更多 -
GABAA Modulator I
Catalog No. A22646 modulator of the GABAA receptor complexGABAA Modulator I is novel modulator of the GABAA receptor complex, and in particular for combating anxiety and related diseases. 了解更多 -
Methoxy-PMS
Catalog No. A22647 active oxygen formation inducerMethoxy-PMS (1-Methoxy PMS), an active oxygen formation inducer, is stable electron-transport mediator between NAD(P)H and tetrazolium dyes. 了解更多 -
Selinexor trans-isomer
Catalog No. A22648 CRM1-selective inhibitorSelinexor trans-isomer is a trans-isomer of Selinexor or KPT-330, which is a CRM1-selective inhibitor of nuclear export. It inhibits protein trafficking from the nucleus and induces cell cycle arrest and apoptosis in mesothelioma cells. 了解更多 -
Des(benzylpyridyl) Atazanavir
Catalog No. A22649 human immunodeficiency virus protease inhibitorDes(benzylpyridyl) Atazanavir is a metabolite of Atazanavir, a human immunodeficiency virus protease inhibitor. 了解更多 -
Tetrabenazine Racemate
Catalog No. A22654 VMAT-2 inhibitorTetrabenazine Racemate (Ro 1-9569 Racemate) is a selective and reversible inhibitor of vesicular monoamine transporter-2 (VMAT-2). 了解更多 -
Loflucarban
Catalog No. A22658 -
4-Oxo-4-HPR
Catalog No. A22669 inhibitor of tubulin polymerization4-Oxo-4-HPR is an inhibitor of tubulin polymerization, inducing marked G2-M cell cycle arrest and apoptosis in fenretinide-sensitive and fenretinide-resistant cell lines. It is also a fenretinide metabolite. 了解更多 -
Nor-benzetimide
Catalog No. A22684 mAChR antagonistNor-benzetimide is a major metabolite of Benzetimide. Benzetimide is a mAChR antagonist with anticholinergic activity. 了解更多 -
(R)-Viloxazine Hydrochloride
Catalog No. A22693 norepinephrine reuptake inhibitor(R)-Viloxazine Hydrochloride is the R-isomer of Viloxazine, a selective norepinephrine reuptake inhibitor (NRI) that can be used as an antidepressant. 了解更多 -
(S)-Viloxazine Hydrochloride
Catalog No. A22694 norepinephrine reuptake inhibitor(S)-Viloxazine Hydrochloride is the S-isomer of Viloxazine, a selective norepinephrine reuptake inhibitor (NRI) that can be used as an antidepressant. 了解更多 -
BLT-1
Catalog No. A22704 type 1 (SR-BI) inhibitorBLT-1, a thiosemicarbazone copper chelator, is a selective scavenger receptor B, type 1 (SR-BI) inhibitor. BLT-1 inhibits the transfer of lipids between high-density lipoproteins (HDL) and cells mediated by SR-BI. BLT-1 is a potent HCV entry inhibitor. 了解更多 -
4'-bromo-Resveratrol
Catalog No. A22709 SIRT1/SIRT3 inhibitor4??-bromo-Resveratrol is a potent inhibitor of the deacetylases sirtuin 1 (SIRT1) and 3 (SIRT3). 了解更多 -
8-Oxocoptisine
Catalog No. A22711 anti-cancer agent8-Oxocoptisine is a natural protoberberine alkaloid with anti-cancer activity. 了解更多 -
Tangshenoside I
Catalog No. A22712 α-glucosidase inhibitory activitiesTangshenoside I, isolated from the roots of Codonopsis lanceolata, exhibits weak α-glucosidase inhibitory activities in vitro with an IC50 of 1.4 mM. 了解更多 -
Diphenylamine hydrochloride
Catalog No. A17701 antioxidant agentDiphenylamine hydrochloride, an organic compound isolated from coriander, is used mainly for its antioxidant properties. Diphenylamine is used as an industrial antioxidant, dye mordant and is also applied in agriculture as a fungicide and antihelmintic. 了解更多 -
Phenazine methylsulfate
Catalog No. A17495 free radical generatorPhenazine methylsulfate is a free radical generator. Phenazine methylsulfate has been used as an electron transfer reactant in cell viability assays. 了解更多 -
Butoconazole nitrate
Catalog No. A11646 imidazole antifungal agentButoconazole nitrate (RS 35887), an imidazole antifungal agent, is active against Candida spp. and effective against vaginal infections due to Candida albicans. Butoconazole nitrate is presumed to function as other imidazole derivatives via inhibition of steroid synthesis. 了解更多 -
Metronidazole
Catalog No. A10585 nitroimidazole antibiotic medicationMetronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa. 了解更多 -
Lonidamine
Catalog No. A11633 antitumor agentLonidamine (AF-1890), an antitumor agent, is a hexokinase, mitochondrial pyruvate carrier (Ki 2.5 μM in isolated rat liver mitochondria) and plasma membrane monocarboxylate transporters inhibitor, which also inhibits mitochondrial complex II. 了解更多 -
Dexrazoxane
Catalog No. A17714 topoisomerase IIα inhibitorDexrazoxane is an intracellular iron chelator and an inhibitor of topoisomerase IIα. 了解更多 -
CFI-402257
Catalog No. A12037 TTK inhibitorCFI-402257, a pyrazolopyridin derivative, has been found to be a TTK inhibitor that could influence chromosome segregation and induce cell death so that is significant in anticancer studies. 了解更多
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