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  • 搜索结果：“A 300”

“A 300”的搜索结果

产品 151 到 200 共 17506个

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  1. 9-ING-41
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    9-ING-41

    Catalog No. A22066
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    glycogen synthase kinase-3β (GSK-3β) inhibitor
    9-ING-41 is a maleimide-based ATP-competitive and selective glycogen synthase kinase-3β (GSK-3β) inhibitor with an IC50 of 0.71 μM. 了解更多
  2. BAY 2416964
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    BAY 2416964

    Catalog No. A22067
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    aryl hydrocarbon receptor (AHR) antagonist
    BAY 2416964 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018146010A1, example 192, has an IC50 of 341 nM. BAY 2416964 has the potential for solid tumors treatment. 了解更多
  3. GSK046
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    GSK046

    Catalog No. A22068
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    BD2 bromodomain inhibitor of the BET proteins
    GSK046 (iBET-BD2) is a potent, selective and orally active BD2 bromodomain inhibitor of the BET proteins, with IC50s of 264 nM (BRD2 BD2), 98 nM (BRD3 BD2), 49 nM (BRD4 BD2) and 214 nM (BRDT BD2), respectively. 了解更多
  4. DiZPK
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    DiZPK

    Catalog No. A22069
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    photocrosslinker
    DiZPK is a photocrosslinker for identifying direct protein-protein interactions in living prokaryotic and eukaryotic cells. 了解更多
  5. CWP232228
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    CWP232228

    Catalog No. A22070
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    Wnt/β-catenin signaling inhibitor
    CWP232228, a highly potent selective Wnt/β-catenin signaling inhibitor, antagonizes binding of β-catenin to T-cell factor (TCF) in the nucleus. 了解更多
  6. HS-243
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    HS-243

    Catalog No. A22071
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    transforming growth factor-?beta kinase inhibitor
    HS-243 is an inhibitor of transforming growth factor-?beta kinase. HS-243 can be used in treatment of cancer, malaria, inflammatory and other TAK1-?mediated diseases. 了解更多
  7. CYM50308
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    CYM50308

    Catalog No. A22072
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    sphingosine-1-phosphate receptor 4 (S1P4-R) agonist
    CYM50308 (ML248) is a potent, selective and high affinity sphingosine-1-phosphate receptor 4 (S1P4-R) agonist with an EC50 of 56 nM. 了解更多
  8. Fluxapyroxad
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    Fluxapyroxad

    Catalog No. A22073
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    the succinate dehydrogenase (SQR) enzyme inhibitor
    Fluxapyroxad, a broad-spectrum fungicide, is an inhibitor of the succinate dehydrogenase (SQR) enzyme. 了解更多
  9. PF9601N
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    PF9601N

    Catalog No. A22075
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    monoamine oxidase B inhibitor
    PF9601N is a selective and potent monoamine oxidase B inhibitor that exhibit anti-Parkinsonian effects in several models of PD. 了解更多
  10. CRANAD-2
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    CRANAD-2

    Catalog No. A22076
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    near-infrared (NIR) probe
    CRANAD-2 is a curcumin-derivatized near-infrared (NIR) probe that meets all the requirements for a NIR contrast agent for the detection of Abeta plaques both in vitro and in vivo. 了解更多
  11. DGY-06-116
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    DGY-06-116

    Catalog No. A22077
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    Src inhibitor
    DGY-06-116 is an irreversible covalent, selective Src inhibitor. 了解更多
  12. HA155
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    HA155

    Catalog No. A22079
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    Autotaxin Inhibitor IV
    HA155, also known as Autotaxin Inhibitor IV, is a boronic acid-based compound that inhibits autotaxin (IC50 = 5.7 nM) by selectively binding to its catalytic threonine. 了解更多
  13. ASN03576800
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    ASN03576800

    Catalog No. A22080
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    ASN03576800 is an inhibitor of the VP40 matrix protein. 了解更多
  14. YMU1
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    YMU1

    Catalog No. A22081
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    human thymidylate kinase (hTMPK) inhibitor
    YMU1 is an inhibitor of human thymidylate kinase (hTMPK). 了解更多
  15. BMS453
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    BMS453

    Catalog No. A22082
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    RARβ agonist
    BMS453 (BMS-189453), a synthetic retinoid, is a RARβ agonist and a RARα/RARγ antagonist. 了解更多
  16. GW779439X
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    GW779439X

    Catalog No. A22083
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    cyclin dependent kinase inhibitor
    GW779439X is an inhibitor of cyclin dependent kinase. 了解更多
  17. 4BP-TQS
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    4BP-TQS

    Catalog No. A22084
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    neuronal nicotinic acetylcholine receptors agonist
    4BP-TQS is an allosteric agonist of α7 subunit-containing neuronal nicotinic acetylcholine receptors (nAChRs). 了解更多
  18. RO2959 hydrochloride
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    RO2959 hydrochloride

    Catalog No. A22085
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    CRAC channel inhibitor
    RO2959 hydrochloride is a potent and selective CRAC channel inhibitor with an IC50 of 402 nM. 了解更多
  19. B355252
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    B355252

    Catalog No. A22086
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    neuroprotective agent
    B355252 is a neuroprotective agent potentiating nerve growth factor (NGF)-induced neurite outgrowth. 了解更多
  20. GW280264X
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    GW280264X

    Catalog No. A22087
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    ADAM17 inhibitor
    GW280264X is an ADAM17 inhibitor. 了解更多
  21. ML191
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    ML191

    Catalog No. A22088
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    GPR55 antagonist
    ML191 (CCG-152883, CID-23612552) is an antagonist of GPR55 with EC50 of 1.076 ?M in U2OS cells overexpressing GPR55. 了解更多
  22. ML298
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    ML298

    Catalog No. A22089
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    Phospholipase D2 (PLD2) inhibitor
    ML298 (CID53393915) is a potent, specific inhibitor of Phospholipase D2 (PLD2) with IC50 of 355 nM. 了解更多
  23. G244-LM
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    G244-LM

    Catalog No. A22090
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    tankyrase 1/2 inhibitor
    G244-LM is a potent and specific tankyrase 1/2 inhibitor that inhibits Wnt signaling. 了解更多
  24. YM26734
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    YM26734

    Catalog No. A22091
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    rabbit platelet sPLA2 inhibitor
    YM-26734 is a rabbit platelet sPLA2 inhibitor that has been used to ameliorate local inflammatory responses in TPA-induced mouse ear edema. 了解更多
  25. CYM 2503
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    CYM 2503

    Catalog No. A22092
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    positive allosteric modulator (PAM)
    CYM2503 is a positive allosteric modulator (PAM) of the GAL2 receptor that potentiates galanin-induced IP1 production in vitro. 了解更多
  26. API-1
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    API-1

    Catalog No. A22093
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    Akt inhibitor
    API-1 (NSC 177223) is a potent inhibitor of Akt that induces GSK3-dependent, β-TrCP- and FBXW7-mediated Mcl-1 degradation, resulting in induction of apoptosis. 了解更多
  27. ML299
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    ML299

    Catalog No. A22094
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    PLD1/PLD2 dual inhibitor
    ML299 (VU0463568) is a dual inhibitor of PLD1 and PLD2 with IC50 of 6 nM and 20 nM, respectively. 了解更多
  28. SW155246
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    SW155246

    Catalog No. A22095
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    DNMT1 inhibitor
    SW155246 is a potent and selective DNMT1 (DNA methyltransferase 1) inhibitor with IC50 of 1.2 μM. SW155246 induces re-expression of the tumor suppressor geneRASSF1 in A549 cells. 了解更多
  29. Apcin
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    Apcin

    Catalog No. A22096
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    E3 ligase activity inhibitor
    Apcin, a ligand of Cdc20, is a potent and competitive anaphase-promoting complex/cyclosome (APC/C(Cdc20)) E3 ligase activity inhibitor. 了解更多
  30. MCC950
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    MCC950

    Catalog No. A22097
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    inhibitor of NLRP3 (NOD-like receptor (NLR) family
    MCC950 (CP-456773, CRID3) is a potent and selective inhibitor of NLRP3 (NOD-like receptor (NLR) family, pyrin domain-containing protein 3) with IC50 of 7.5 nM and 8.1 nM in BMDMs and HMDMs, respectively. 了解更多
  31. RBC10
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    RBC10

    Catalog No. A22098
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    inhibitor of Ral binding to RALBP1
    RBC10 is an inhibitor of Ral binding to RALBP1 (the effector). 了解更多
  32. NIBR-0213
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    NIBR-0213

    Catalog No. A22099
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    S1P(1) antagonist
    NIBR-0213 is a potent and selective antagonist of S1P(1) with efficacy in experimental autoimmune encephalomyelitis. 了解更多
  33. SR8278
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    SR8278

    Catalog No. A22100
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    nuclear heme receptor REV-ERB synthetic antagonist
    SR8278 is a competitive nuclear heme receptor REV-ERB synthetic antagonist. 了解更多
  34. BPU-11
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    BPU-11

    Catalog No. A22101
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    HCN4 CLP ligand
    BPU-11 is a HCN4 CLP ligand. It acts by modulating channel function and completely abolishing the cAMP-induced shift in V1/2. 了解更多
  35. CRANAD-28
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    CRANAD-28

    Catalog No. A22102
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    two-photon imaging probe
    CRANAD-28, a blood brain barrier (BBB) penetrable two-photon imaging probe, acts by labelling plaques and cerebral amyloid angiopathies (CAAs). 了解更多
  36. PD-089828
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    PD-089828

    Catalog No. A22103
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    ATP competitive inhibitor of FGFR-1, PDGFR-β and EGFR
    PD089828 is an ATP competitive inhibitor of FGFR-1, PDGFR-β and EGFR with IC50 of 0.15 ?M, 1.76 ?M, and 5.47 ?M, respectively. 了解更多
  37. RY785
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    RY785

    Catalog No. A22104
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    inhibitor of Kv2.1 and Kv2.2
    RY785 (Kv2-IN-A1) is an inhibitor of Kv2.1 and Kv2.2. 了解更多
  38. WAY-169916
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    WAY-169916

    Catalog No. A22105
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    pathway-selective inhibitor of estrogen receptor (ER)
    WAY-169916 is a pathway-selective inhibitor of estrogen receptor (ER) that acts by inhibiting NF-kB transcriptional activity. 了解更多
  39. SGA360
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    SGA360

    Catalog No. A22106
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    modulator of aryl hydrocarbon (Ah) receptor
    SGA360 is a selective modulator of aryl hydrocarbon (Ah) receptor that exhibits anti-inflammatory properties. 了解更多
  40. JCP174
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    JCP174

    Catalog No. A22107
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    depalmitoylase inhibitor
    JCP174 is a depalmitoylase inhibitor that enhances Toxoplasma host-cell invasion by targeting TgPPT1. 了解更多
  41. AEM1
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    AEM1

    Catalog No. A22108
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    inhibitor of deregulated NRF2 transcriptional activity
    AEM1 is an inhibitor of deregulated NRF2 transcriptional activity in cancer. 了解更多
  42. PS210
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    PS210

    Catalog No. A22109
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    protein kinase PDK1 inhibitor
    PS210 is a substrate-selective protein kinase PDK1 inhibitor that acts by binding to the PIF-pocket allosteric docking site. 了解更多
  43. RH01687
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    RH01687

    Catalog No. A22110
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    β-cell protector
    RH01687 is a potent β-cell protector that exhibits β-cell-protective activities against endoplasmic reticulum (ER) stress. 了解更多
  44. BRD6688
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    BRD6688

    Catalog No. A22111
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    HDAC2 inhibitor
    BRD6688 is a selective inhibitor of HDAC2 that acts by enhancing the learning and memory processes. 了解更多
  45. Creatine riboside
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    Creatine riboside

    Catalog No. A22112
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    urinary metabolite
    Creatine riboside is a urinary metabolite and is a diagnostic and prognostic biomarker of lung cancer. 了解更多
  46. ONO-8130
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    ONO-8130

    Catalog No. A22113
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    antagonist of EP1 receptor
    ONO-8130 is an orally available antagonist of EP1 receptor. 了解更多
  47. MSBN
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    MSBN

    Catalog No. A22114
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    fluorogenic probe
    MSBN is a highly selective fluorogenic probe for thiols, selectively imaging thiols in live cells and specifically label protein thiols with a turn-on signal to determine diverse reversible protein thiol modifications. 了解更多
  48. Cytosporone B
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    Cytosporone B

    Catalog No. A22115
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    nuclear orphan receptor Nur77/NR4A1 agonist
    Cytosporone B (Csn-B; Dothiorelone G) is a naturally occurring nuclear orphan receptor Nur77/NR4A1 agonist with an EC50 of 0.278 nM. 了解更多
  49. GSK106 hydrochloride
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    GSK106 hydrochloride

    Catalog No. A22116
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    negative control compound
    GSK106 is a negative control compound that can be used in binding and functional assays for PAD4 inhibitors. 了解更多
  50. GSK121 trifluoroacetate
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    GSK121 trifluoroacetate

    Catalog No. A22117
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    PAD4 inhibitor
    GSK121 trifluoroacetate is a selective inhibitor of PAD4. 了解更多

产品 151 到 200 共 17506个

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