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PNU-159682
Catalog No. A22023 ADCs cytotoxinPNU-159682, a highly potent metabolite of the anthracycline nemorubicin (DNA topoisomerase II inhibitor) with outstanding cytotoxicity, is a potent ADCs cytotoxin. 了解更多 -
GSK1940029
Catalog No. A20820 SCD inhibitorGSK1940029 (SCD inhibitor 1) is a stearoyl-coa desaturase (SCD) inhibitor extracted from patent WO/2009060053 A1, compound example 16. 了解更多 -
WAY-204688
Catalog No. A20757 NF-κB inhibitorWAY-204688 is an estrogen receptor (ER-α) selective, orally active inhibitor of NF-κB transcriptional activity with an IC50 of 122?±?30 nM for NF-κB-luciferase (NF-κB-luc) in HAECT-1 cells. 了解更多 -
Zaurategrast ethyl ester
Catalog No. A20624 α4β1/α4β7 integrin antagonistZaurategrast ethyl ester (CDP323), the ethyl ester prodrug of CT7758, is a α4β1/α4β7 integrin antagonist used for the treatment of inflammatory and autoimmune disorders. 了解更多 -
Allopurinol riboside
Catalog No. A20572 Allopurinol riboside, a metabolite of allopurinol, shows potent activities against parasites. 了解更多 -
ICI 153110
Catalog No. A20513 phosphodiesterase inhibitorICI 153110 is an orally active phosphodiesterase inhibitor with both vasodilating and inotropic properties which is designed for the treatment of congestive cardiac failure. 了解更多 -
Bisantrene
Catalog No. A20419 Bisantrene is a highly effective antitumor drug, targets eukaryotic type II topoisomerases. 了解更多 -
Revizinone
Catalog No. A20398 PDE inhibitorRevizinone is a novel selective phosphodiesterase (PDE) inhibitor with IC50 values on this enzyme to 0.036 microM. 了解更多 -
Closthioamide
Catalog No. A20385 DNA gyrase inhibitorClosthioamide is a potent inhibitor of bacterial DNA gyrase and highly active against Ec, MRSA, VRE and Mv), with MICs of 9.00 μM, 0.58 μM, 0.58 μM and 72.03 μM respectively. 了解更多 -
Heparastatin
Catalog No. A20376 -
Dolutegravir intermediate-1
Catalog No. A20351 integrase inhibitorDolutegravir is an integrase inhibitor developed for the treatment of human immunodeficiency virus (HIV)-l infection. 了解更多 -
MY-5445
Catalog No. A20349 -
Diacylglycerol acyltransferase inhibitor-1
Catalog No. A20315 DGAT1 inhibitorDiacylglycerol acyltransferase inhibitor-1 is a diacylglycerol acyltransferase (DGAT1) inhibitor. 了解更多 -
Nebicapone
Catalog No. A20279 COMT inhibitorNebicapone (BIA 3-202), a reversible catechol-O-methyltransferase (COMT) inhibitor, is mainly metabolized by glucuronidation. 了解更多 -
Tefinostat
Catalog No. A20258 pan HDAC inhibitorTefinostat (CHR-2845) is a monocyte/macrophage-targeted pan HDAC inhibitor, cleaved into active acid CHR-2847 by the intracellular esterase human carboxylesterase-1 (hCE-1). Anti-monocytoid lineage leukaemias activity. 了解更多 -
α-2,3-sialyltransferase-IN-1
Catalog No. A20249 α-2,3-sialyltransferase inhibitorα-2,3-sialyltransferase-IN-1 (Lith-O-Asp analog) is a noncompetitive α-2,3-sialyltransferase inhibitor with an IC50 of 6 μM. 了解更多 -
Dot1L-IN-2
Catalog No. A20231 Dot1L inhibitorDot1L-IN-2 is a potent, selective and orally bioavailable inhibitor of Dot1L (a histone methyltransferase), with an IC50 and Ki of 0.4 nM and 0.08 nM, respectively. 了解更多 -
MAT2A inhibitor 1
Catalog No. A20226 MATA2 inhibitorsMAT2A inhibitor 1 is a methionine adenosyltransferase 2A (MATA2) inhibitor with an IC50 less than l00 nM. 了解更多 -
MAT2A inhibitor 2
Catalog No. A20171 MAT2A inhibitorMAT2A inhibitor 2 is a methionine adenosyltransferase 2A (MAT2A) inhibitor. 了解更多 -
Jaspamycin
Catalog No. A20153 PKA activatorJaspamycin (7-CN-7-C-Ino) is a potent activator of PKA, binding to the R site (PKAR), with an EC50 of 6.5 nM and Kd of 8 nM in Trypanosoma brucei. Jaspamycin (7-CN-7-C-Ino) does not bind with purified human PKARIα. Anti-parasite activity. 了解更多 -
4,4'-Dimethoxybenzil
Catalog No. A20145 hiCE inhibitor4,4'-Dimethoxybenzil is a human intestinal carboxyl esterase (hiCE) inhibitor with Ki of 70 nM. 了解更多 -
TMPyP4 tosylate
Catalog No. A20124 telomerase inhibitorTMPyP4 tosylate (TMP 1363) is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines. 了解更多 -
Intoplicine
Catalog No. A20104 DNA topoisomerase I/II inhibitorIntoplicine is a DNA topoisomerase I and II inhibitor. 了解更多 -
Acetylhydrolase-IN-1
Catalog No. A20063 acetylhydrolase inhibtorAcetylhydrolase-IN-1 is a 1-Alkyl-2-acetylglycerophosphocholine esterase (Alkylacetyl-GPC: acetylhydrolase) inhibtor. 了解更多 -
MGAT2-IN-1
Catalog No. A19983 MGAT2 inhibitorMGAT2-IN-1 is an orally active inhibitor of monoacylglycerol acyltransferase (MGAT2) with IC50 of 7.8 and 2.4 nM for human and mouse MGAT2, respectively. 了解更多 -
Reproxalap
Catalog No. A19978 RASP sequestering agentReproxalap (ADX-102) is a reactive aldehyde species (RASP) sequestering agent for the treatment of dry eye. Reproxalap (ADX-102) covalently binds aldehydes including malondialdehyde and 4-hydroxynonenal. 了解更多 -
UDP-GlcNAc Disodium Salt
Catalog No. A19951 OGT donor substrateUDP-GlcNAc Disodium Salt (UDP-α-D-N-Acetylglucosamine Disodium Salt) is a donor substrate of O-GlcNAc transferase (OGT). 了解更多 -
N4-Acetylcytidine triphosphate
Catalog No. A19880 N4-Acetylcytidine triphosphate is efficiently used as a substrate in T7 Polymerase-catalyzed in vitro transcription and can be incorporated into multiple templates. 了解更多
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