“AG 013736”的搜索结果

产品 301 到 350 共 3341个

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  1. Maytansinol

    Catalog No. A20767
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    microtubule depolymerizing agent
    Maytansinol, also known as Ansamitocin P-0, is a potent microtubule depolymerizing agent. 了解更多
  2. ABT-670

    Catalog No. A20765
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    dopamine D4 receptor agonist
    ABT-670 is a selective, oral bioavailable agonist of dopamine D4 receptor, with EC50 of 89 nM, 160 nM, and 93 nM for human?D4, ferret?D4, and rat?D4, respectively. 了解更多
  3. SB-616234A

    Catalog No. A20764
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    5-HT1B receptor antagonist
    SB-616234A is a selective and orally bioavailable 5-HT1B receptor antagonist, with anxiolytic and antidepressant activity. 了解更多
  4. AMG-009

    Catalog No. A20759
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    prostaglandin D2 antagonist
    AMG-009 is a potent antagonist of prostaglandin D2, with IC50 of 3 nM and 12 nM for CRTH2 and DP receptors, respectively. 了解更多
  5. TG4-155

    Catalog No. A20758
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    EP2 receptor antagonist
    TG4-155 is a potent, brain-permeant and selective EP2 receptor antagonist with a Ki of 9.9 nM. 了解更多
  6. GSK2018682

    Catalog No. A20752
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    S1P1/S1P5 receptor agonist
    GSK2018682 is an agonist for S1P1 and S1P5 receptor with pEC50s of 7.7 and 7.2, respectively, and has no agonist activity towards human S1P2, S1P3, or S1P4. GSK2018682 is used in the research of multiple sclerosis. 了解更多
  7. ACH-806

    Catalog No. A20750
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    NS4A antagonist
    ACH-806 is an NS4A antagonist which can inhibit Hepatitis C Virus (HCV) replication with an EC50 of 14 nM. 了解更多
  8. MB-07344

    Catalog No. A20748
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    TR-β agonist
    MB-07344 is a thyroid hormone receptor (TR)-β agonist with a binding affinity Ki of 2.17 nM. 了解更多
  9. KML29

    Catalog No. A20746
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    MAGL inhibitor
    KML29 is a potent and selective MAGL inhibitor with IC50 = 5.9, 15, and 43 nM in human, mouse, and rat brain proteomes, respectively. 了解更多
  10. GR79236

    Catalog No. A20745
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    adenosine A1 receptor agonist
    GR79236 is a highly potent and selective adenosine A1 receptor agonist (Ki = 3.1 nM) that has analgesic and anti-inflammatory actions in humans and animals. 了解更多
  11. Seladelpar

    Catalog No. A20744
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    PPAR-δ agonist
    Seladelpar (MBX-8025) is an orally active, potent (50% effect concentration EC50 2 nM), and specific PPAR-δ agonist. 了解更多
  12. 9-Azido-Neu5DAz

    Catalog No. A20741
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    imaging agent
    9-Azido-Neu5DAz is a non-natural bifunctional carbohydrates as imaging agent. 了解更多
  13. Duocarmycin MA

    Catalog No. A20738
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    antibody drug conjugates (ADCs) toxin
    Duocarmycin MA is an antibody drug conjugates (ADCs) toxin. Duocarmycin is a DNA alkylating agent that binds in the minor groove. Duocarmycin MA can be used against multi-drug resistant cell lines. 了解更多
  14. CV-159

    Catalog No. A20731
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    dihydropyridine Ca2+ antagonist
    CV-159 is a unique dihydropyridine Ca2+ antagonist with an anti-calmodulin (CaM) action, and has antiinflammatory activities. 了解更多
  15. TA-1801

    Catalog No. A20729
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    hypolipidemic agent
    TA-1801 is a hypolipidemic agent. 了解更多
  16. CP-66948

    Catalog No. A20728
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    histamine H2-receptor antagonist
    CP-66948 is a histamine H2-receptor antagonist with gastric antisecretory activity and mucosal protective properties. 了解更多
  17. Trombodipine

    Catalog No. A20725
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    Trombodipine is an antithrombotic agent. 了解更多
  18. SM-6586

    Catalog No. A20723
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    calcium channel antagonist
    SM-6586 is a calcium channel antagonist and inhibitor of Na+/H+ and Na+/Ca2+ exchange transport, potentially for the treatment of cerebrovasular diseases and hypertension. 了解更多
  19. Ru-32514

    Catalog No. A20722
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    benzodiazepine receptor agonist
    Ru-32514 is an agonist of benzodiazepine receptor. 了解更多
  20. FPR Agonist 43

    Catalog No. A20720
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    dual FPR1/FPR2/ALX agonist
    FPR Agonist 43 (compound 43) is a dual formyl peptide receptor 1 (FPR1) and formyl peptide receptor 2 (FPR2)/ALX agonist. 了解更多
  21. Ro-24-0238

    Catalog No. A20719
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    thromboxane synthesis inhibitor
    Ro-24-0238 is an antagonist of platelet activating factor (PAF) and inhibitor of thromboxane synthesis, used for lessening the inflammation and damage resulting from a local release of PAF. 了解更多
  22. Ro-24-4736

    Catalog No. A20717
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    PAF antagonist
    Ro 24-4736 is a potent, selective, p.o.-active platelet-activating factor (PAF) antagonist with a long duration of action. 了解更多
  23. NSP-805

    Catalog No. A20716
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    PDE3 inhibitor
    NSP-805 is a potent and selective inhibitor of guinea pig cardiac phosphodiesterase 3 (PDE3), and a cardiotonic agent with vasodilator properties. 了解更多
  24. RG-12915

    Catalog No. A20715
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    5-HT3 antagonist
    RG-12915 is a selective 5-HT3 antagonist, with IC50 value of 0.16 nM. 了解更多
  25. CL-275838

    Catalog No. A20711
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    memory-enhancing agent
    CL-275838 is a memory-enhancing agent, also with potent antidepressant activities. 了解更多
  26. BMY-43748

    Catalog No. A20710
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    antibacterial agent
    BMY-43748 is a promising antibacterial agent, exhibiting great in vitro and in vivo antibacterial activity. 了解更多
  27. SC-52012

    Catalog No. A20709
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    fibrinogen receptor antagonist
    HY-19163 is an orally active fibrinogen receptor antagonist, with antiplatelet activities. 了解更多
  28. Perzinfotel

    Catalog No. A20708
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    NMDA receptor antagonist
    Perzinfotel (EAA-090) is a potent, selective, and competitive NMDA receptor antagonist with neuroprotective effects. Perzinfotel (EAA-090) shows high affinity (IC50=30 nM) for the glutamate site. 了解更多
  29. Fezolinetant

    Catalog No. A20706
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    NK3R antagonist
    Fezolinetant is an antagonist of the neurokinin 3 receptor (NK3R), used for the treatment of menopausal hot flushes. 了解更多
  30. Terbogrel

    Catalog No. A20705
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    thromboxane A2 synthase inhibitor
    Terbogrel is an orally available thromboxane A2 receptor antagonist and a thromboxane A2 synthase inhibitor, with both IC50s of about 10 nM. 了解更多
  31. CS-003 Free base

    Catalog No. A20704
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    triple tachykinin receptor antagonist
    CS-003 Free base (CS-003), a triple tachykinin receptor antagonist, shows high affinities for human (Neurokinin) NK1, NK2 and NK3 receptors with Ki values of 2.3 nM, 0.54 nM and 0.74 nM, respectively. 了解更多
  32. L-159282

    Catalog No. A20703
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    nonpeptide angiotensin II receptor antagonist
    L-159282 is a highly potent, orally active, nonpeptide angiotensin II receptor antagonist, with anti-hypertensive activity. 了解更多
  33. CP-105696

    Catalog No. A20701
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    Leukotriene B4 Receptor antagonist
    CP-105696 is a potent and selective Leukotriene B4 Receptor antagonist, with an IC50 of 8.42 nM. 了解更多
  34. Elisartan

    Catalog No. A20697
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    Elisartan is an orally active non-peptide pro-drug of angiotensin II AT1 receptor antagonist HN-12206, and shows anti-hypertension activities. 了解更多
  35. GSK2256294A

    Catalog No. A20696
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    recombinant human sEH inhibitor
    GSK2256294A is a potent, reversible, tight binding inhibitor of isolated recombinant human sEH (soluble epoxide hydrolase) (IC50 = 27 pM; t1/2 = 121 min) and displays potent inhibition against the rat (IC50 = 61 pM) and murine (IC50 = 189 pM) orthologs of sEH. 了解更多
  36. Pumaprazole

    Catalog No. A20693
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    proton pump antagonist
    Pumaprazole is a reversible proton pump antagonist. 了解更多
  37. Pumosetrag Hydrochloride

    Catalog No. A20692
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    5-HT3 partial agonist
    Pumosetrag Hydrochloride (MKC-733; DDP-733) is an orally available 5-HT3 partial agonist developed for the treatment of irritable bowel syndrome and gastroesophageal reflux disease. 了解更多
  38. Setmelanotide

    Catalog No. A20689
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    MC4R agonist
    Setmelanotide (RM-493; BIM-22493; IRC-022493) is a selective melanocortin 4 receptor (MC4R) agonist with EC50s of 0.27 nM and 0.28 nM for human and rat MC4R, respectively. 了解更多
  39. GLP-1R Antagonist 1

    Catalog No. A20679
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    glucagon-like peptide 1 receptor antagonist
    GLP-1R Antagonist 1 (compound 5d) is an orally active, CNS penetrant and non-competitive antagonist of glucagon-like peptide 1 receptor (GLP-1R), with an IC50 of 650 nM. 了解更多
  40. R-IMPP

    Catalog No. A20678
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    anti-secretagogue of PCSK9
    R-IMPP is an anti-secretagogue of PCSK9 (IC50=4.8 μM), which targets the 80S ribosome to inhibit PCSK9 protein translation. 了解更多
  41. BAL-30072

    Catalog No. A20677
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    BAL-30072, a siderophore sulfactam, is a monocyclic beta-lactam antibiotic, with activity against multiresistant gram-negative bacilli. 了解更多
  42. FPTQ

    Catalog No. A20674
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    mGluR1 antagonist
    FPTQ is mGluR1 antagonist with IC50 of 6 nM and 1.4 nM for human and mouse mGluR1 respectively. 了解更多
  43. 1-BCP

    Catalog No. A20672
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    memory-enhancing agent
    1-BCP is a centrally active drug that modulates AMPA receptor gated currents. 1-BCP is a memory-enhancing agent. 了解更多
  44. Nucleoside-Analog-1

    Catalog No. A20671
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    Nucleoside-Analog-1 is a 4??-Azidocytidine analogue against Hepatitis C virus replication. 了解更多
  45. CHPG

    Catalog No. A20667
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    mGluR5 agonist
    CHPG is a selective mGluR5 agonist, and attenuates SO2-induced oxidative stress and inflammation through TSG-6/NF-κB pathway in BV2 microglial cells. 了解更多
  46. Nucleoside-Analog-2

    Catalog No. A20666
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    Nucleoside-Analog-2 is a 4'-Azidocytidine analogue against Hepatitis C virus (HCV) replication. 了解更多
  47. Sultopride

    Catalog No. A20663
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    dopamine D2 receptor antagonist
    Sultopride (LIN-1418) is a selective antagonist of dopamine D2 receptor. 了解更多
  48. 5-FAM

    Catalog No. A20660
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    fluorescent derivatization reagent
    5-FAM (5-Carboxyfluorescein) contains a carboxylic acid that can be used to react with primary amines via carbodiimide activation of the carboxylic acid. Fluorescein is the most common fluorescent derivatization reagent for labeling biomolecules. 了解更多
  49. JNJ-18038683

    Catalog No. A20659
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    5-HT7 receptor antagonist
    JNJ-18038683 is a 5-Hydroxytryptamine Type 7 (5-HT7) receptor antagonist, with pKis of 8.19, 8.20 for rat and human 5-HT7 in HEK293 cells, respectively. 了解更多
  50. ITX5061

    Catalog No. A20651
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    p38 MAPK inhibitor
    ITX5061 is a type II inhibitor of p38 MAPK and also an antagonist of scavenger receptor B1 (SR-B1). 了解更多

产品 301 到 350 共 3341个

每页
页面:
  1. 5
  2. 6
  3. 7
  4. 8
  5. 9

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