“17”的搜索结果

产品 351 到 400 共 2939个

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  1. PD173212

    Catalog No. A19317
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    VSCC blocker
    PD173212 is a selective N-type voltage sensitive calcium channel (VSCC) blocker, with an IC50 of 36 nM in IMR-32 assays. 了解更多
  2. 2'-Deoxypseudoisocytidine

    Catalog No. A19311
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    2'-Deoxypseudoisocytidine is a nucleoside analogue. 了解更多
  3. NIK SMI1

    Catalog No. A19308
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    NIK inhibitor
    NIK SMI1 is a potent, selective NF-κB inducing kinase (NIK) inhibitor, which inhibits NIK-catalyzed hydrolysis of ATP to ADP with IC50 of 0.23±0.17 nM. 了解更多
  4. PH-002

    Catalog No. A19297
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    apo inhibitor
    PH-002 is an inhibitor of apolipoprotein (apo) E4 intramolecular domain interaction in neuronal cells that could rescue impairments of mitochondrial motility and neurite outgrowth. 了解更多
  5. Loreclezole

    Catalog No. A19295
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    GABAA receptor modulator
    Loreclezole, an antiepileptic compound, is a selective GABAA receptor modulator and acts as a positive allosteric modulator of β2 or β3-subunit containing receptors. 了解更多
  6. Aminomalonic acid

    Catalog No. A19289
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    Aminomalonic acid is an amino endogenous metabolite, acts as a strong inhibitor of L-asparagine synthetase from Leukemia 5178Y/AR (Ki= 0.0023 M) and mouse pancreas (Ki= 0.0015 M) in vitro. 了解更多
  7. AZ PFKFB3 26

    Catalog No. A19281
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    PFKFB3 inhibitor
    AZ PFKFB3 26 is a potent and selective inhibitor of the metabolic kinase PFKFB3 with an IC50 of 23 nM. AZ PFKFB3 26 inhibits PFKFB1 and PFKFB2 with IC50s of 2.06 and 0.384 μM, respectively. 了解更多
  8. Trk-IN-4

    Catalog No. A19277
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    pan-Trk inhibitor
    Trk-IN-4 (PF-6683324 isomer) is a potent pan-Trk inhibitor in cell-based assays with IC50s of 1.9 nM, 2.6 nM and 1.1 nM for TrkA, TrkB and TrkC, respectively. Anti-hyperalgesic effect. 了解更多
  9. Adavivint

    Catalog No. A19257
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    Wnt signaling inhibitor
    Adavivint (SM04690; Lorecivivint) is a potent and selective inhibitor of canonical Wnt signaling, with an EC50 of 19.5 nM via a high-throughput TCF/LEF-reporter assay in SW480 colon cancer cells. 了解更多
  10. Gefapixant

    Catalog No. A19254
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    P2X3R antagonist
    Gefapixant is an orally active P2X3 receptor (P2X3R) antagonist with IC50s of ~30 nM versus recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors. 了解更多
  11. TC HSD 21

    Catalog No. A19236
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    17β-HSD3 inhibitor
    TC HSD 21 is a potent 17β-hydroxysteroid dehydrogenase type 3 (17β-HSD3) inhibitor with an IC50 of 14 nM. TC HSD 21 shows excellent selectivity over 17β-HSD isoenzymes and nuclear receptors. 了解更多
  12. NE 52-QQ57

    Catalog No. A19231
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    GPR4 antagonist
    NE 52-QQ57 is a selective, and orally available GPR4 antagonist with an IC50 of 70 nM. Anti-inflammatory activities. 了解更多
  13. AZ-3

    Catalog No. A19217
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    JAK1 inhibitor
    AZ-3 is a potent and selective JAK1 inhibitor with an IC50 of 34 nM. 了解更多
  14. 13-cis-N-[4-(Ethoxycarbonyl)phenyl]retinamide

    Catalog No. A19207
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    derivative of Retinoic acid
    13-cis-N-[4-(Ethoxycarbonyl)phenyl]retinamide is a derivative of Retinoic acid. 了解更多
  15. TLR7 agonist 1

    Catalog No. A19201
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    TLR7 agonist
    TLR7 agonist 1 is a potent, selective and oral TLR7 agonist with an IC50 of 90 nM. 了解更多
  16. GPR40 agonist 1

    Catalog No. A19192
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    GPR40 full agonist
    GPR40 agonist 1 is a potent and novel GPR40 full agonist with an EC50 of 2 nM and 17 nM for hGPR40 and rGPR40, respectively. 了解更多
  17. 3'-Azido-3'-deoxy-5-fluorocytidine

    Catalog No. A19191
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    cytidine derivative
    3'-Azido-3'-deoxy-5-fluorocytidine (Compound 12) is a cytidine derivative. 了解更多
  18. MC-Alkyl-Hydrazine Modified MMAF

    Catalog No. A19179
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    MC-Alkyl-Hydrazine Modified MMAF is a drug-linker conjugate for ADC with potent antitumor activity by using the Modified MMAF (a tubulin inhibitor), linked via the noncleavable MC-Alkyl-Hydrazine. 了解更多
  19. Cholestenone

    Catalog No. A19178
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    Cholestenone is the intermediate oxidation product of cholesterol. 了解更多
  20. H-Ile-Pro-Pro-OH

    Catalog No. A19177
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    H-Ile-Pro-Pro-OH, a milk-derived peptide, inhibits angiotensin-converting enzyme (ACE)with an IC50 of 5 μM. Antihypertensive tripeptides. 了解更多
  21. CYT-1010

    Catalog No. A19176
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    mu-opioid receptor agonist
    CYT-1010 is a mu-opioid receptor agonist extracted from patent WO2013173730A2, with EC50s of 13.1 nM and 0.0053 nM on beta-arrestin recruitment and inhibition of cAMP production, respectively. 了解更多
  22. 2-Iminobiotin

    Catalog No. A19175
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    nitric oxide synthases inhibitor
    2-Iminobiotin (Guanidinobiotin) is a biotin (vitamin H or B7) analog. 2-Iminobiotin is a reversible nitric oxide synthases inhibitor with Kis of 21.8 and 37.5μM for murine iNOS and rat n-cNOS, respectively. 了解更多
  23. J22352

    Catalog No. A19174
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    HDAC6 inhibitor
    J22352 is a PROTAC (proteolysis-targeting chimeras)-like and highly selective HDAC6 inhibitor with an IC50 value of 4.7 nM. 了解更多
  24. Nicotinic acid mononucleotide

    Catalog No. A19173
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    Nicotinic acid mononucleotide (NAMN) is formed from nicotinic acid (NA) via the nicotinic acid phosphoribosyltransferase in the biosynthesis of NAD+. Nicotinate mononucleotide is a substrate for nicotinamide mononucleotide/Nicotinic acid mononucleotide adenylyltransferase. 了解更多
  25. AZ1508

    Catalog No. A19172
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    tubulin inhibitor
    AZ1508 is a drug-linker conjugates for ADC for the treatment of breast and stomach cancer, and the drug is a tubulin inhibitor. 了解更多
  26. Suberylglycine

    Catalog No. A19171
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    Suberylglycine is an acyl glycine, which is a normally minor metabolite of fatty acid. 了解更多
  27. AT-1002

    Catalog No. A19170
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    AT-1002, a 6-mer synthetic peptide, is a tight junction regulator and absorption enhancer. 了解更多
  28. TAM-IN-2

    Catalog No. A19162
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    TAM inhibitor
    TAM-IN-2 is a TAM inhibitor extracted from patent US 20170275290 A1, pyrrolotriazine compound 0904. 了解更多
  29. LHVS

    Catalog No. A19147
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    cysteine protease inhibitor
    LHVS is a potent, non-selective cysteine protease inhibitor. LHVS effectively blocks T. gondii microneme protein secretion (IC50=10 μM), gliding motility, and cell invasion. 了解更多
  30. Nitroaspirin

    Catalog No. A19145
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    Nitroaspirin (NCX 4016) is a nitric oxide (NO) donor and a nitro-derivative of Aspirin, which combines with Nitroaspirin to inhibit cyclooxygenase. Nitroaspirin (NCX 4016) has antithrombotic and anti-platelet properties and acts as a direct and irreversible inhibitor of COX-1. 了解更多
  31. (R)-Serine

    Catalog No. A17978
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    NMDA glutamate receptor co-agonist
    (R)-Serine, an endogenous amino acid involved in glia-synapse interactions that has unique neurotransmitter characteristics, is a potent co-agonist at the NMDA glutamate receptor. 了解更多
  32. Cephradine monohydrate

    Catalog No. A17949
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    Cephradine monohydrate (Cefradine monohydrate) is a first generation cephalosporin, which is active against a wide range of Gram positive and Gram-negative bacteria. 了解更多
  33. 2-Methylhexanoic acid

    Catalog No. A17815
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    2-methylhexanoic acid is a medium-chain fatty acid and is used as flavouring. 了解更多
  34. Hydroquinine

    Catalog No. A17533
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    Hydroquinine is a cinchona alkaloid, can be used in the preparation of its derivatives such as C9 epihydroquinine, 9-acetoxy-10,11-dihydroquinine and 10,11-dihydroquinine monohydrochloride. 了解更多
  35. Pi-Methylimidazoleacetic acid hydrochloride

    Catalog No. A21732
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    Pi-Methylimidazoleacetic acid hydrochloride is a potential neurotoxin. 了解更多
  36. (3-Carboxypropyl)trimethylammonium chloride

    Catalog No. A21725
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    (3-Carboxypropyl)trimethylammonium chloride is angiopathic substance produced as an intermediary metabolite by gut microbiota that feed on carnitine in dietary red meat. 了解更多
  37. Tecalcet Hydrochloride

    Catalog No. A21404
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    Tecalcet Hydrochloride (R 568 Hydrochloride), an orally active calcimimetic compound, allosterically and positively modulates the calcium-sensing receptor (CaSR). 了解更多
  38. Ionomycin calcium

    Catalog No. A21370
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    Ionomycin calcium (SQ23377 calcium) is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. 了解更多
  39. 4-Azido-L-phenylalanine

    Catalog No. A21332
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    4-Azido-L-phenylalanine is an unnatural amino acid, which is used as an effective vibrational reporter of local protein environments. 了解更多
  40. Naphthoquine phosphate

    Catalog No. A21331
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    Naphthoquine phosphate is antimalarial drug. 了解更多
  41. Pozanicline

    Catalog No. A21318
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    Pozanicline (ABT-089) selectively activate neuronal nicotinic acetylcholine receptor (nAChR) subtypes, is a novel cholinergic agent that is a partial agonist at α4β2* nAChRs (Ki=16 nM) and shows high selectivity for α6β2* and α4α5β2 nAChR subtypes, the binding affinity (Ki, rat) for Pozanicline to [3H] cytisine sites is 16.7 nM. 了解更多
  42. Glyparamide

    Catalog No. A21317
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    Glyparamide is a chlorophenyl-containing sulfonylurea with hypoglycemic activity; Glyparamide rarely causes hepatic injury. 了解更多
  43. TMB

    Catalog No. A21310
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    TMB (BM blue) is a chromogenic substrate used in staining procedures in immunohistochemistry as well as being a visualising reagent used in enzyme-linked immunosorbent assays (ELISA). 了解更多
  44. Dolastatin 10

    Catalog No. A21273
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    Dolastatin 10 (DLS 10) is a potent antimitotic peptide, isolated from the marine mollusk Dolabela auricularia, that inhibits tubulin polymerization. 了解更多
  45. (S)-Rasagiline

    Catalog No. A21272
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    (S)-Rasagiline (TVP1022) is the S-isomer of Rasagiline, which is an anti-Parkinson drug, appears to have the same neuroprotective activity as the R-isomer, but is 1000-fold less active as an MAO-B inhibitor. 了解更多
  46. RX-3117

    Catalog No. A21259
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    RX-3117(TV-1360; Fluorocyclopentenylcytosine) is novel a cytidine analog; shows anticancer activity in several cancer cell lines, including gemcitabine-resistant variants. 了解更多
  47. Tulathromycin A

    Catalog No. A21187
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    Tulathromycin A is a macrolide antibiotic. 了解更多
  48. Olesoxime

    Catalog No. A21179
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    Olesoxime (TRO 19622) is a mitochondrial-targeted neuroprotective compound with mean EC50 value for increasing cell survival is 3.2±0.2μM. 了解更多
  49. Cipargamin

    Catalog No. A21176
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    Cipargamin (NITD609) is an potent antimalarial compound, with IC50 of appr 1 nM against P. falciparum. 了解更多
  50. GNF179

    Catalog No. A21042
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    GNF179 is an optimized 8,8-dimethyl IP analog that exhibited the potency(4.8 nM against the multidrug resistant strain W2) in vitro metabolic stability and in vivo oral bioavailability. 了解更多

产品 351 到 400 共 2939个

每页
页面:
  1. 6
  2. 7
  3. 8
  4. 9
  5. 10

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