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Cytoskeleton

Cytoskeleton

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ELR510444

Catalog No. A15455
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Microtubule Disruptor

ELR510444是一种新型的微管破坏剂；抑制MDA-MB-231细胞增殖，IC50为30.9 nM；而不是P-糖蛋白药物转运蛋白的底物，并在过量表达ΔIII-微管蛋白的细胞系中保留活性。了解更多

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Vinblastine sulfate

Catalog No. A13661
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microtubule dynamics 抑制剂

Vinblastine sulfate在无细胞试验中抑制微管形成并抑制nAChR活性，IC50为8.9μM，用于治疗某些类型的癌症。了解更多

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DM1-Sme

Catalog No. A15960
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maytansinoid microtubular 抑制剂

DM1-SMe是一种有效的美登木素生物碱微管抑制剂，是未结合的DM1，是与硫代甲烷混合的二硫化物，用于封端巯基。了解更多

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TRx0237 (LMTX) mesylate

Catalog No. A16124
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tau protein aggregation 抑制剂

TRx0237 (LMTX) mesylate是第二代tau蛋白聚集抑制剂，可用于治疗阿尔茨海默氏病（AD）和额颞痴呆。了解更多

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Tasidotin hydrochloride

Catalog No. A21944
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microtubule assembly and microtubule dynamics inhibitor

Tasidotin hydrochloride is a peptide analog of the antimitotic depsipeptide dolastatin 15, as an inhibitor of microtubule assembly and microtubule dynamics. 了解更多

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CK-869

Catalog No. A20970
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Arp2/3 complex inhibitor

CK-869 is an Actin-Related Protein 2/3 (ARP2/3) complex inhibitor, with an IC50 of 7 μM. 了解更多

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CK-666

Catalog No. A20973
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Arp2/3 complex inhibitor

CK-666 is a cell-permeable inhibitor of actin-related protein Arp2/3 complex, and binds to Arp2/3 complex, stabilizes the inactive state of the complex, blocking movement of the Arp2 and Arp3 subunits into the activated filament-like (short pitch) conformation. 了解更多

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Entasobulin

Catalog No. A21027
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??-tubulin polymerization inhibitor

Entasobulin is a β-tubulin polymerization inhibitor with potential anticancer activity. 了解更多

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- 最新产品
TR-14035

Catalog No. A17118
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Integrin 拮抗剂

TR-14035是α4β7和α4β1整联蛋白的双重拮抗剂。了解更多

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