Sirtuins

Catalog No.Inhibitor Name SIRT1SIRT2SIRT3SirtuinOther
A10377Selisistat (EX 527)
****
A12226Sirtinol
*
**
A15902SirReal2
****
A14221Splitomicin
**
A14225AGK2
***
A12305Tenovin-6
***
*
p53

Notes:
1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

5 个项目

每页

设置升序顺序
  1. AGK2

    Catalog No. A14225
    Quick View
    SIRT2 抑制剂
    AGK2是一种有效的选择性SIRT2抑制剂,IC50为3.5μM。 了解更多
  2. Sirtinol

    Catalog No. A12226
    Quick View
    sirtuin 抑制剂
    Sirtinol是Sirtinol NAD依赖组蛋白去乙酰化酶的细胞渗透性特异性抑制剂。在无细胞分析中,它是一种特异性SIRT1和SIRT2抑制剂,IC50分别为131 μM和38 μM。 了解更多
  3. AK-1

    Catalog No. A14370
    Quick View
    SIRT2 抑制剂
    AK-1比SIRT1和SIRT3选择性抑制SIRT2。 了解更多
  4. AK-7

    Catalog No. A12904
    Quick View
    SIRT2 抑制剂
    AK-7是SIRT2的细胞和脑渗透抑制剂(IC50 = 15.5 μM)。 了解更多
  5. SirReal2

    Catalog No. A15902
    Quick View
    Selective SIRT2 抑制剂
    SirReal2是一种有效的、同型选择性Sirt2抑制剂,IC50为140 nM。 了解更多

5 个项目

每页

设置升序顺序
Rewards